TLR3 Is a Negative Regulator of Immune Responses Against Paracoccidioides brasiliensis [PDF]
Frontiers in Cellular and Infection Microbiology, 2019 Toll-like receptors (TLRs) comprise the best-characterized pattern-recognition receptor (PRR) family able to activate distinct immune responses depending on the receptor/adaptor set assembled.
Sandro Rogerio De Almeida +2 more
exaly +4 more sources
Polypeptides Targeting Paracoccidioides brasiliensis Drk1. [PDF]
J Fungi (Basel), 2023 Considering the toxicity of conventional therapeutic approaches and the importance of precise mechanistic targets, it is important to explore signaling pathways implicated in fungal pathobiology. Moreover, treatment of paracoccidioidomycosis, a systemic mycosis caused by a dimorphic fungus, requires prolonged therapeutic regimens.
Marcos CM +8 more
europepmc +4 more sources
Clinical features and genetic background of the sympatric species Paracoccidioides brasiliensis and Paracoccidioides americana [PDF]
PLoS Neglected Tropical Diseases, 2019 INTRODUCTION:The agents of paracoccidioidomycosis, historically identified as Paracoccidioides brasiliensis, are in fact different phylogenetic species.
Rosely Zancope-Oliveira +2 more
exaly +2 more sources
Paracoccidioides brasiliensis Isolated from Nine-Banded Armadillos (Dasypus novemcinctus) Reveal Population Structure and Admixture in the Amazon Basin [PDF]
Journal of Fungi, 2021 Paracoccidioidomycosis is an endemic fungal disease to Latin America caused by at least five species-level genotypes of Paracoccidioides, named P. lutzii, P. brasiliensis (S1a and S1b populations), P. americana, P. restrepiensis, and P. venezuelensis. In
Eduardo Bagagli +9 more
doaj +2 more sources
Molecular eco-epidemiology of Paracoccidioides brasiliensis in road-killed mammals reveals Cerdocyon thous and Cuniculus paca as new hosts harboring this fungal pathogen. [PDF]
PLoS ONE, 2021 Wild animals infected with Paracoccidioides brasiliensis represent important indicators of this fungal agent presence in the environment. The detection of this pathogen in road-killed wild animals has shown to be a key strategy for eco-epidemiological ...
Bruno de Souza Scramignon-Costa +9 more
doaj +2 more sources
PLoS Neglected Tropical Diseases, 2020 Genotyping of the genus Paracoccidioides showed its diversity and geographical distribution. Four species constituting the Paracoccidioides brasiliensis complex and Paracoccidioides lutzii are etiological agents of paracoccidioidomycosis (PCM).
Rinaldo Poncio Mendes +2 more
exaly +2 more sources
PLoS ONE, 2019 BACKGROUND:Paracoccidioidomycosis (PCM) is a systemic mycosis commonly found in Latin America that is caused by distinct species of Paracoccidioides genus: Paracoccidioides brasiliensis complex (S1, PS2, PS3 and PS4) and Paracoccidioides lutzii.
Eva Bürger +2 more
exaly +2 more sources
Apendicitis por Paracoccidioides brasiliensis
Revista Médica Herediana, 2006 La paracoccidioidomicosis es la micosis más prevalente en Sudamérica. La forma aguda afecta el sistema fagocítico mononuclear de niños y personas inmunocomprometidas.
Ana Beatriz MUÑOZ URRIBARRI +3 more
doaj +3 more sources
Fast and cost-effective protocol to produce Paracoccidioides spp. antigens
Biomédica: revista del Instituto Nacional de Salud, 2023 Introduction. The existing methods for Paracoccidioides spp. antigen production are problematic in terms of standardization, specificity, stability, repeatability, and reproducibility. Objective.
Karolina Rosa Fernandes-Beraldo +2 more
doaj +1 more source
Paracoccidioides brasiliensis AND Paracoccidioides lutzii, A SECRET LOVE AFFAIR [PDF]
Revista do Instituto de Medicina Tropical de São Paulo, 2015 SUMMARYTo commemorate Prof. Carlos da Silva Lacaz's centennial anniversary, the authors have written a brief account of a few, out of hundreds, biological, ecological, molecular and phylogenetic studies that led to the arrival of Paracoccidioides lutzii, hidden for more than a century within Paracoccidioides brasiliensis.
ARANTES, Thales Domingos +4 more
openaire +4 more sources