Results 251 to 260 of about 321,253 (331)

Thorncliffe Formation: A proglacial to subglacial lacustrine basin sequence, Greater Toronto Region, Canada

open access: yesBoreas, EarlyView.
Map of Lower sediment (LS) thickness is a surrogate for the distribution of Thorncliffe Formation (TF) and ~75% of TF thickness from the slope of Niagara Escarpment east to Brighton. Inset images show the LS sequence at the Don Valleys brickyards (DVBY) and undeformed TF sand and gravel (~15 m) below Newmarket Till (NT) at sites L and Co.
David R. Sharpe   +3 more
wiley   +1 more source

PDE4D and PDE3B orchestrate distinct cAMP microdomains in 3T3‐L1 adipocytes

open access: yesBritish Journal of Pharmacology, EarlyView.
Basal conditions: •Ins/PDE3B lowers cytoplasmic cAMP (cyt‐cAMP) without affecting plasma membrane cAMP (pm‐cAMP). •Insulin decreases lipid droplet cAMP (LD‐cAMP) independent of PDE3B. •FGF1/PDE4D modestly reduces both cyt‐ and pm‐cAMP, while PDE4D alone can modulate LD‐cAMP. ISO stimulation: •Ins/PDE3B has minimal impact on cyt‐cAMP.
Johannes Krier   +9 more
wiley   +1 more source

Endotheliopathy in systemic sclerosis: from endothelium-dependent vasodilation to the dysfunction of the vascular reserve, is the paradise lost? [PDF]

open access: yesArthritis Res Ther
Bandini G   +5 more
europepmc   +1 more source

Advancing Design Science for Multi‐Actor Innovation Processes: Structuring Ecosystem Model Innovation for Transformative Change

open access: yesCreativity and Innovation Management, EarlyView.
ABSTRACT Addressing complex societal challenges, such as sustainability, requires more than merely descriptive or explanatory research. It demands methods that provide structured and actionable guidance for innovation processes, enabling diverse actors to jointly imagine and enact transformative change.
Britt Smulders   +3 more
wiley   +1 more source

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