Results 121 to 130 of about 956,237 (293)

Evaluation of the Dual Impact of Nanotechnologies on Health and Environment Through Alternative Bridging Models

open access: yesAdvanced Healthcare Materials, EarlyView.
This review explores how alternative invertebrate and small‐vertebrate models advance the evaluation of nanomaterials across medicine and environmental science. By bridging cellular and organismal levels, these models enable integrated assessment of toxicity, biodistribution, and therapeutic performance.
Marie Celine Lefevre   +3 more
wiley   +1 more source

Dynamic, Reconfigurable, and Hierarchical Biosynthetic Composites via Collagen Self‐Assembly within Highly Crowded Microgel Pastes

open access: yesAdvanced Materials, EarlyView.
A new approach to extracellular matrix‐mimetic, hierarchical biomaterials is presented. Soft gels composed of overpacked hydrogel microparticle arrays present a biomolecularly crowded environment permissive to the self‐assembly of collagen networks.
Elif Narbay   +11 more
wiley   +1 more source

A Biochar‐Based Composite Hydrogel Microenvironment for Enhanced Biocatalysis

open access: yesAdvanced Materials, EarlyView.
This work presents the synthesis of a polyacrylamide hydrogel wherein biomass‐derived biochar is co‐encapsulated with the enzyme horseradish peroxidase (HRP). The resulting composite hydrogel possesses balanced electron‐rich and electron‐deficient domains, creating an optimal microenvironment that concentrates both hydrogen peroxide and phenol ...
Shengzhe Wang   +9 more
wiley   +1 more source

Microenvironment Modulation‐Based Nanomaterial‐Loaded Hydrogel Dressings for Diabetic Foot Ulcers: Research Progress and Future Perspectives

open access: yesAdvanced Materials Interfaces, EarlyView.
xx xx. ABSTRACT Diabetic foot ulcer (DFU) is a chronic complication of diabetes, primarily caused by hyperglycemia, peripheral vascular disease, and neuropathy. Characterized by persistent hyperglycemia, impaired perfusion, inflammation, and infection, DFUs pose significant challenges to healing and are associated with high morbidity and amputation ...
Tang Yuqing   +5 more
wiley   +1 more source

Engineered Microfluidic Organoid Systems: New Paradigms for Menopause Mechanism Research and Personalized Medicine

open access: yesAdvanced Materials Technologies, EarlyView.
This review explores the integration of microfluidic technology with organoid systems as an innovative platform for studying menopausea complex multi‐organ condition. By enabling precise simulation of inter‐organ communication and hormone responses, microfluidic organoids offer a physiologically relevant model for investigating menopausal syndrome and ...
Qianyi Zhang   +4 more
wiley   +1 more source

Complex Collective Decisions and the Probability of Collective Inconsistencies [PDF]

open access: yes
Many groups are required to make collective decisions over multiple interconnected propositions. The "doctrinal paradox" or "discursive dilemma" shows that propostionwise majority voting can lead to inconsistent collective outcomes, even when the ...
Christian List
core  

From Lab to Landscape: Environmental Biohybrid Robotics for Ecological Futures

open access: yesAdvanced Robotics Research, EarlyView.
This Perspective explores environmental biohybrid robotics, integrating living tissues, microorganisms, and insects for operation in real‐world ecosystems. It traces the leap from laboratory experiments to forests, wetlands, and urban environments and discusses key challenges, development pathways, and opportunities for ecological monitoring and ...
Miriam Filippi
wiley   +1 more source

La génesis de las parafilias sexuales y la homosexualidad egodistónica: el Modelo de los Mecanismos Tensionales

open access: yesAvances en Psicología Latinoamericana, 2012
Across the development of Tension Mechanism Model, based on Experiential Avoidance (Hayes, Wilson, Gifford, Follette & Stroshal, 1996) and Conductual Finished Theory proposed by McConaghy (1980), the present article tries to expose a sequence of ...
Rafael Jiménez Díaz
doaj  

RIG‐I Mediated Neuron‐Specific IFN Type 1 Signaling in FUS‐ALS Induces Neurodegeneration and Offers New Biomarker‐Driven Individualized Treatment Options for (FUS‐)ALS

open access: yesAdvanced Science, EarlyView.
Using iPSC‐derived motoneurons and postmortem tissue from FUS‐ALS patients, it is demonstrated that increased mitochondrial transcription leads to elevated cytosolic double‐stranded RNA (dsRNA) levels. This aberrant accumulation activates a RIG‐I–dependent innate immune response leading to neurodegeneration, which is amenable for FDA‐ and EMA‐approved ...
Marcel Naumann   +26 more
wiley   +1 more source

Indole‐3‐Propionic Acid Improves Alveolar Development Impairment via Targeting VAMP8‐mediated SNAREs Complex Formation in Bronchopulmonary Dysplasia

open access: yesAdvanced Science, EarlyView.
This study aims to evaluate the impact of the tryptophan‐derived metabolite indole‐3‐propionic acid (IPA) on lung development and autophagic flux. IPA alleviates hyperoxia‐induced alveolar arrest by promoting autophagosome‐lysosome fusion via inhibition of VAMP8 phosphorylation, which is suggestive of a promising therapeutic target of BPD.
Beibei Wang   +14 more
wiley   +1 more source

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