Results 161 to 170 of about 212,315 (316)
Bridging the Electroclinical Paradox to Precision Care by Elucidating Seizure Network Dynamics. [PDF]
J Clin NeurolKim JB, Kim BJ.
europepmc +1 more source
Advanced Science, EarlyView.This study identifies ESM1 as an endogenous anticoagulant that modulates venous thrombosis. It shows that ESM1 deficiency triggers vascular occlusion in zebrafish and mice, whereas its restoration or overexpression prolongs clot‐formation time. Mechanistic analyses reveal that ESM1 activates HCII through its dermatan‐sulfate chain, uncovering a ...
Changsheng Chen +10 more
wiley +1 more source
BMI Is Unreliable When Studying the Obesity Paradox in TAVR. [PDF]
JACC AsiaKhlidj Y +3 more
europepmc +1 more source
Executive Brief: China's 2027 Paradox - Fiscal Constraints and Military Window Strategic Analysis
Finks, Christopher
openalex +1 more source
Advanced Science, EarlyView.This study designed a tumor microenvironment‐responsive AIEgen nanoparticle for near‐infrared photoimmunotherapy, which inhibits primary tumors and metastasis by promoting pyroptosis and suppressing aerobic glycolysis. ABSTRACT In advanced osteosarcoma, tumor invasion often prevents complete resection, and immunotherapy is limited by the tumor's ...
Kaiyuan Liu +14 more
wiley +1 more source
The Diagnostic Gap Between Clinical and Pathological Extranodal Extension in Head and Neck Cancers: A 5-Year Nationwide Trend Analysis in Taiwan. [PDF]
J Pers MedLin HF, Hung SH.
europepmc +1 more source
Connexin43 Deficiency Leads to Ventricular Arrhythmias by Reprogramming Proline Metabolism
Advanced Science, EarlyView.The study demonstrated that connexin43 (Cx43) knockout caused arrhythmic phenotype and decreased proline content in vitro and in vivo. Mechanistically, Cx43 interacts with the amino acid transporter SNAT2 (sodium‐dependent neutral amino acid transporter), and its deficiency disrupts proline transport and metabolism.
Hangying Ying +8 more
wiley +1 more source