Results 221 to 230 of about 212,315 (316)

To be born or not to be born? : the paradox of the Catholic Church in the Philippines

, 2014
Alexienne Fuhrmann
openalex   +1 more source

Paradoxical pain.

BMJ, 1993
Hanks, G W, O'Neill, W M, Fallon, M T
openaire   +3 more sources

Decoding the Cardiac Immune Microenvironment and Fibroblast Crosstalk in Radiotherapy Combined with Immunotherapy‐Induced Cardiac Fibrosis Based on Single‐Cell Transcriptomic Analysis

Advanced Science, EarlyView.
This study highlights that radioimmunotherapy drives crosstalk between fibroblasts and immune cells (especially macrophages) in the cardiac microenvironment, with IL‐6 as the key mediator, and tocilizumab alleviates cardiac fibrosis by targeting this interplay.
Yuxi Luo, Ying Yu, Zhimin Zeng, Yanxin Chen, Yali Yi, Zhiqin Lu, Fujuan Zeng, Peng Xu, Daya Luo, Leifeng Chen, Anwen Liu   +10 more
wiley   +1 more source

The TH1/TH2 Response Imbalance Zika Virus Pathogenesis: An Immunological Paradox. [PDF]

APMIS
Menezes C, Martins L, Ferro G, Arnaud B, Quaresma J, Vasconcelos P, Sousa J.   +6 more
europepmc   +1 more source

The Open-Security Paradox of Digital Agility: How Data Orchestration and Algorithm Transparency Influence Ransomware Resilience in Open Innovation Ecosystems

Zhonghua Sheng, Anand Jeyaraj
openalex   +1 more source

Elevated TRIM25 Impairs Poly (ADP‐ribose) Metabolism via PARG Degradation and Mediates Compression‐Induced Intervertebral Disc Degeneration

Advanced Science, EarlyView.
TRIM25 acts as a multifunctional hub driving intervertebral disc degeneration under mechanical stress. Mechanical compression significantly upregulates TRIM25 expression, establishing it as a key E3 ubiquitin ligase platform. TRIM25 targets PARG and Ku80 via distinct molecular interfaces, triggering their ubiquitination and degradation.
Zhangrong Cheng, Haiyang Gao, Wenbo Wu, Pengzhi Shi, Xianglong Chen, Zimu Yu, Wang Wu, Kangcheng Zhao, Cao Yang, Yukun Zhang   +9 more
wiley   +1 more source

Why does the signal-to-noise paradox exist in seasonal climate predictability?

Yashas Shivamurthy, Subodh Kumar Saha, Samir Pokhrel, Mahen Konwar, Utkarsh Verma   +4 more
openalex   +1 more source

Direct Extracellular Matrix Modulation Attenuates Intestinal Fibrosis via a Fibronectin‐Targeted Approach

Advanced Science, EarlyView.
Fibronectin regulates the extracellular matrix (ECM)–myofibroblast cycle through three key steps: (1) its secretion and assembly by myofibroblasts (inhibited by pUR4); (2) collagen deposition along its scaffold (inhibited by R1R2); and (3) integrin α5β1‐mediated mechanotransduction (inhibited by ATN161).
Wenlong Ma, Siyu Yang, Tengkai Wang, Di Zhang, Hewei Wu, Shichen Fu, Xiaohan Wan, Lixiang Li, Xiuli Zuo, Yanqing Li, Jiaoyang Lu   +10 more
wiley   +1 more source

Targeting Obesity for Heart Failure. [PDF]

Eur Cardiol
Morris E, Rider O.
europepmc   +1 more source

Paradox Reactor Power Plant: A Paradox Engine (PE) Application

Fairweather, Stormy, Recurro, Continuance, Prime, Ara   +3 more
openalex   +1 more source