Results 251 to 260 of about 212,315 (316)

Integrating Spatial Proteogenomics in Cancer Research

Advanced Science, EarlyView.
Xx xx. ABSTRACT Background: Spatial proteogenomics marks a paradigm shift in oncology by integrating molecular analysis with spatial information from both spatial proteomics and other data modalities (e.g., spatial transcriptomics), thereby unveiling tumor heterogeneity and dynamic changes in the microenvironment.
Yida Wang, Yang Wu, Feng Zhang, Parthiban Periasamy, Haiyue You, Denise Goh, Rachel Elizabeth Ann Fincham, Xin Ning, Danping Wu, Lu Liu, Ying Jiang, Zhiwen Qian, Joe Yeong, Yan Zhang   +13 more
wiley   +1 more source

Paradoxes weaken the International Association for the Study of Pain definition of pain. [PDF]

Korean J Pain
Cohen ML, Weisman A, Quintner JL.
europepmc   +1 more source

The Environmental Security Paradox: the conflict between achieving economic growth and securing the environment

, 2020
Carmen Meza
openalex   +1 more source

Glutamine Deprivation Triggers Tribbles Homolog 3 Dependent G‐Quadruplex Resolution to Maintain DNA Repair and Tumor Survival

Advanced Science, EarlyView.
Glutamine deprivation triggers transient DNA damage yet activates adaptive repair in hepatocellular carcinoma cells. We identify TRIB3 as a stress‐induced nuclear scaffold that associates with DDX5 and G‐quadruplex DNA atBRCA1 andRAD51AP1 promoters. TRIB3 loss increases G4 accumulation, suppresses HR gene transcription, elevates γ‐H2A.X, and sensitizes
Qiang Ji, Xuedan Sun, Zhangran Sun, Mengfan Li, Xinyu Cheng, Shuai Tian, Rick F. Thorne, Jinming Li, Guangzhi Liu, Mian Wu, Xiaoying Liu   +10 more
wiley   +1 more source

Stem Cell and Exosome Therapy in Wound Healing: Traps, Paradoxes, and Tricks Transforming Paradigms. [PDF]

Biomedicines
Velikic G, Supic G, Maric DL, Puletic M, Maric MD, Barac B, Maric DM.   +6 more
europepmc   +1 more source

Profiling Localized Immunomodulation and Drug Biodistribution within a Subcutaneous Vascularized Niche for Cell Transplantation

Advanced Science, EarlyView.
We studied how five common immunosuppressants behave when delivered directly to a transplant site instead of systemically. Using a vascularized implant for islet transplantation, we show that local delivery protects grafts, limits drug spread to the rest of the body, and produces distinct immune signatures.
Jocelyn Nikita Campa‐Carranza, Simone Capuani, Melissa A. Willman, Alexander Rabassa, Ashley L. Joubert, Tommaso Bo, Letizia Franco, Marzia Conte, Ana L. Anaya‐García, Gabrielle E. Rome, Rim Ouni, Henry J. Seaborne, Camden A. Caffey, Dora M. Berman, Junjun Zheng, Jesus Paez‐Mayorga, Corrine Ying Xuan Chua, Shu Hsia Chen, Norma S. Kenyon, Alessandro Grattoni   +19 more
wiley   +1 more source

The obesity paradox revisited - influence on the results of percutaneous coronary interventions. [PDF]

AsiaIntervention
Movahed MR, Nathan A, Hashemzadeh M.
europepmc   +1 more source

The Becker Paradox and Type I vs. Type II Errors in the Economics of Crime

, 2006
Mats Persson, Claës-Henric Siven
openalex   +1 more source

Commentary: Perceptions and needs of patients, caregivers and health professionals regarding an oncology community center: a qualitative study. [PDF]

Front Public Health
Xu S, Wang J, Zhao W, Wu W.
europepmc   +1 more source

« Contre Sainte-Beuve et les paradoxes du rhétorique »

, 2004
Stéphane Chaudier
openalex   +1 more source