Results 251 to 260 of about 1,405,451 (393)

The knowledge-symptom paradox in urinary incontinence: a health literacy and equity challenge in urban Southeast Asia. [PDF]

BMC Public Health
Komon W, Chonwarangkoon P, Saraluck A.
europepmc   +1 more source

The paradox of caught-in-the-act surveillance scenes: dilemmas of police video surveillance in Rio de Janeiro

, 2012
Bruno Cardoso
openalex   +2 more sources

Ammonia Detoxification Inhibits Liver Metastasis by Reshaping Hepatic Microenvironment

Advanced Science, EarlyView.
Liver metastasis diverts aspartate into hyperactive pyrimidine synthesis, disrupting urea cycling and causing pathogenic ammonia accumulation. Ammonia dually reprograms the microenvironment by: (1) activating hepatic stellate cells (HSCs) into pro‐fibrotic metastasis‐associated fibroblasts (MAFs), and (2) suppressing anti‐tumor monocytes/macrophages ...
Sumin Sun, Haili Hu, Long Chen, Yuan Gao, Peng Sun, Liming Chen   +5 more
wiley   +1 more source

Letter to the editor regarding to 'the impact of body mass index on the efficacy of CDK4/6 inhibitors in patients with metastatic breast cancer'. [PDF]

Ann Med
Wei Q, Li D.
europepmc   +1 more source

Paradoxical aging in HIV: immune senescence of B Cells is most prominent in young age

, 2017
Stefano Rinaldi, Suresh Pallikkuth, Varghese K. George, Lesley R. de Armas, Rajendra Pahwa, Celeste M. Sanchez, Maria Pallin, Li Pan, Nicola Cotugno, Gordon M. Dickinson, Allan Rodríguez, Margaret A. Fischl, María L. Alcaide, Louis Gonzalez, Paolo Palma, Savita Pahwa   +15 more
openalex   +2 more sources

Hepatocyte BDNF Acts as a Novel Immune Checkpoint to Restrain TLR4‐Mediated Acute Hepatitis

Advanced Science, EarlyView.
This study identifies hepatocyte‐derived BDNF as an endogenous TLR4 antagonist that alleviates acute hepatitis. BDNF is downregulated in hepatocytes via REST‐mediated transcriptional repression during ALI/ALF. Mechanistically, BDNF binds to TLR4 on macrophages to suppress inflammation.
Weiwei Zhu, Yaqian Cui, Yongqiang Zhou, Yihui Zheng, Lijiang Huang, Leiming Jin, Qianhui Zhang, Pan Chen, Mengsha Lin, Jiaxi Ye, Yongqiang Xiong, Joo Young Huh, Xiang Hu, Xiaokun Li, Wu Luo, Guang Liang   +15 more
wiley   +1 more source

When healthy classrooms hurt: how reduced bullying isolates victimized youth through altered friendship and status dynamics. [PDF]

BMC Psychol
Hoffmann T, Basa B, Kollár KN.
europepmc   +1 more source

The Environmental Security Paradox: the conflict between achieving economic growth and securing the environment

, 2020
Carmen Meza
openalex   +1 more source

Immune Checkpoint Inhibitors and Immunomodulators for Cancer Immunotherapy: Insights Into Resistance and Therapeutic Strategies

Advanced Science, EarlyView.
The schematic diagram illustrates the roles of novel immune checkpoints, immunomodulatory factors, cell death and multimodal technologies in cancer immunotherapy. Abstract Cancer immunotherapy has redefined cancer treatment. However, the molecular and cellular basis of immune evasion and therapeutic resistance remains incompletely understood.
Fangquan Chen, Yang Yu, Xiutao Cai, Junhao Lin, Ruirui Liang, Rui Kang, Daolin Tang, Jiao Liu   +7 more
wiley   +1 more source

Obesity paradox in patients with non-ST-elevation myocardial infarction undergoing percutaneous coronary intervention: A nationwide retrospective observational study. [PDF]

Am Heart J Plus
Moore S, Thakkar A, Notta S, Snipp J, McGuire C, Vedantam V, Jbara MH.   +6 more
europepmc   +1 more source