Results 171 to 180 of about 13,387 (263)

Hypoxia‐induced vulnerability of the somatosensory nervous system

open access: yesThe Journal of Physiology, EarlyView.
Abstract figure legend Sensory neurons are highly energy dependent and rely on sufficient oxygen availability to maintain metabolic stability and effective neurocommunication. Within the somatosensory system, even modest reductions in tissue oxygen tension impair neuronal respiration, forcing a shift toward less efficient metabolic pathways that ...
Jack Corbett, Richard P. Hulse
wiley   +1 more source

Surgical Versus Conservative Management for Carpal Tunnel Syndrome: An Updated Systematic Review of Randomised Trials. [PDF]

open access: yesBrain Sci
Masiero S   +9 more
europepmc   +1 more source

Low‐threshold cutaneous mechanoreceptors on the foot sole have enhanced sensitivity when skin temperature is elevated

open access: yesThe Journal of Physiology, EarlyView.
Abstract figure legend Schematic illustration of microneurography recordings used to examine the effects of local skin heating on cutaneous mechanoreceptor responses in the human foot (left panel). A microelectrode inserted into a peripheral nerve records single‐unit activity from tactile afferent fibres while controlled mechanical stimuli are applied ...
Erika E. Howe   +4 more
wiley   +1 more source

Synchrony within Aβ mechanoreceptor subtypes governs signal propagation to primary somatosensory cortex

open access: yesThe Journal of Physiology, EarlyView.
Abstract figure legend We used an optogenetic gain‐of‐function manipulation to investigate how sensory signals from two subtypes of Aβ low threshold mechanoreceptors (LTMRs) contribute to the cortical representation of touch. CatCh, a sensitive and fast channelrhodopsin variant, enables pulsed‐light generation of high‐frequency action potential trains ...
Wanyi Liu   +2 more
wiley   +1 more source

A Clinically Aligned Two‐Stage Machine Learning Framework for Predicting Hungry Bone Syndrome After Parathyroidectomy

open access: yesEndocrinology, Diabetes &Metabolism, Volume 9, Issue 5, September 2026.
A clinically aligned two‐stage machine learning framework integrates preoperative and perioperative features to predict hungry bone syndrome after parathyroidectomy. Explainable risk stratification may support individualised calcium management and early intervention for high‐risk patients.
Shih‐Min Yin   +10 more
wiley   +1 more source

Is It Safe to Have Deep Brain Stimulation after MRI-Guided Focused Ultrasound Ablation? A Report of Three Cases and Review of Literature.

open access: yesStereotact Funct Neurosurg
Yuen J   +7 more
europepmc   +1 more source

Combination Pharmacotherapies for Obesity—Current Evidence and Future Directions

open access: yesEndocrinology, Diabetes &Metabolism, Volume 9, Issue 5, September 2026.
Combination pharmacotherapy for obesity can enhance weight loss by targeting complementary neuroendocrine and metabolic pathways. Such benefits are largely additive but limited by tolerability, cost and access. This review outlines practical clinical archetypes and a research agenda for safer, more precise and durable combination strategies across ...
A. B. M. Kamrul‐Hasan   +6 more
wiley   +1 more source

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