Results 171 to 180 of about 594,103 (247)

Cobalt/Photoredox Catalyzed Desymmetrization of Oxo and Azabicycles via Asymmetric Reductive Coupling With Alkynes

Advanced Science, EarlyView.
A one‐step, asymmetric reductive coupling of alkynes and oxa‐ and aza‐bicyclic olefins using a cobalt/photoredox catalytic system through desymmetrization. ABSTRACT Bicyclo[2.2.1]heptane frameworks represent a privileged structural motif prevalent in numerous natural products and bioactive molecules.
Subhankar Pradhan, Arko Saha, Bholanath Maity, Sayan Dutta, Luigi Cavallo, Basker Sundararaju   +5 more
wiley   +1 more source

Whole-slide mapping of tumor tissue fiber architecture via computational scattered light imaging. [PDF]

Biomed Opt Express
Abbasi H, Ettema L, van Elk R, Eskes M, Doukas M, Koppes SA, Keereweer S, Menzel M.   +7 more
europepmc   +1 more source

BIN1 and ALDH1B1 Deficiency in Colonic Smooth Muscle Drives Mitochondrial Dysfunction and Fibrosis in Slow‐Transit Constipation

Advanced Science, EarlyView.
Slow‐transit constipation (STC) is a disabling motility disorder with unclear smooth‐muscle mechanisms. Spatial proteomic analysis of STC patient colon reveals both the central pathogenic role of smooth muscle cells (SMCs) in STC and novel regulators of intestinal motility, BIN1 and ALDH1B1.
Jianbo Liu, Hao Zhang, Wenhao Qiao, Ran Liu, Jie Sun, Xiaopei Li, Qin Li, Dongbo Zhao, Dawei Chen, Jingxin Li, Shuxiao Dong   +10 more
wiley   +1 more source

Fix or freeze? Spectral differences arising from tissue preparation in chemical imaging.

Analyst
Zheng T, Adi W, Campagnola PJ, Yesilkoy F.   +3 more
europepmc   +1 more source

Robust immunohistochemical detection of α-synuclein, tau and amyloid-β in human brain tissue archived for up to 78 years. [PDF]

Free Neuropathol
Just MK, Christensen KB, Wirenfeldt M, Steiniche T, Parkkinen L, Myllykangas L, Borghammer P.   +6 more
europepmc   +1 more source

Single‐Cell Transcriptomic Analysis of Tumor Heterogeneity and the Microenvironment in Pseudomyxoma Peritonei

Advanced Science, EarlyView.
This study presents a single‐cell atlas of pseudomyxoma peritonei spanning primary and paired metastatic lesions. Distinct epithelial substates, stromal remodeling, immune exclusion, lipid metabolic reprogramming, and a candidate angiogenic network were identified in metastatic lesions.
Xi Li, Lei Wang, Lei Ai, Zimeng Li, Zhaochangci Chen, Yuchen Luo, Tianran Zhang, Mengjia Liao, Songhao Wang, Jiajia Cui, Ke Liu, Chengxian Guo, Guodong Liu, Jiye Yin, Wei Wu   +14 more
wiley   +1 more source

Early Isoflurane Exposure Is Associated With Delayed Adolescent Neurobehavioral Deficits, Accompanied by Dysregulation of FOXG1 and EB3. [PDF]

Dev Neurobiol
Chen K, Xia M, Li C, Ren Z, Li X.
europepmc   +1 more source

Laboratory-based cellular-level correlative visible-light and X-ray microscopy for 3D evaluation of mouse kidney biopsy. [PDF]

Sci Rep
Kunishima N, Hirose R, Takeda Y, Ito K, Furuichi K, Omote K.   +5 more
europepmc   +1 more source

Glial cell mapping in the camel cerebellar cortex: a histochemical and immunohistochemical study. [PDF]

Sci Rep
Attaai AH, Noreldin AE, Nomir AG, Hussein MT.   +3 more
europepmc   +1 more source

Study on Preparation and Performance Testing of Silica-Composite Organic Phase Change Material Microcapsules. [PDF]

Polymers (Basel)
Chen L, Li J, Zhu L, Zhu Y.
europepmc   +1 more source