Results 81 to 90 of about 872,810 (292)

Melt-extruded polyethylene oxide (PEO) rods as drug delivery vehicles: Formulation, performance as controlled release devices and the influence of co-extruded excipients on drug release profiles [PDF]

, 2012
The utility of controlled release medication formulations lies in their ability to keep drugs at steady levels in the blood plasma of recipients and within the termini of the maximum and minimum effective therapeutic levels.
Mucalo, Michael R., Rathbone, Michael J.
core   +1 more source

Deciphering transcriptional plasticity in pancreatic ductal adenocarcinoma reveals alterations in sensory neuron innervation

Molecular Oncology, EarlyView.
Pancreatic sensory neurons innervating healthy and PDAC tissue were retrogradely labeled and profiled by single‐cell RNA sequencing. Tumor‐associated innervation showed a dominant neurofilament‐positive subtype, altered mitochondrial gene signatures, and reduced non‐peptidergic neurons.
Elena Genova, Michele Montrone, Uday Rangaswamy, Francesco Diversi, Irene Schiavo, Denise Ferrarini, Roberta Di Florio, Irene Longo, Michele Coscia, Nicola Zamboni, Giorgia Demontis, Lisa Veghini, Vincenzo Corbo, Remo Sanges, Paul Heppenstall   +14 more
wiley   +1 more source

Angiotensinergic innervation of rat and human mesenteric resistant blood vessels [PDF]

, 2007
In contrast to the current believe that angiotensin II (Ang II) only interacts with the sympathetic nervous system (SNS) as a circulating hormone, we document here the existence of an endogenous renin-angiotensin system (RAS) in the sympathetic coeliac ...
Eva Heiniger, Hans Imboden, Jaspal Patil, Oliver Muhlemann, Thomas Schaffner   +4 more
core   +1 more source

CCDC80 suppresses high‐grade serous ovarian cancer migration via negative regulation of B7‐H3

Molecular Oncology, EarlyView.
PAX8 is a lineage‐specific master regulator of transcription in high‐grade serous ovarian cancer (HGSC) progression. We show for the first time that PAX8 facilitates proliferation and metastasis by repressing the cell autonomous tumor suppressor CCDC80 and inducing B7‐H3 expression.
Aya Saleh, Nitzan Medina‐Itzhaki, Milena Chekov, Eden Gal‐Swisa, Roba Gabesh‐Wahabi, Inbar Savyon, Inna Naroditsky, Hilary A. Kenny, Basem Fares, Lina Korsensky, Einav Girsh, Liron Berger, Ruth Perets   +12 more
wiley   +1 more source

Gamma ray production in paraffin by cosmic rays [PDF]

Gamma ray production in paraffin by cosmic ...
Chupp, E. L., Forrest, D. J., Lavakare, P. J.   +2 more
core   +1 more source

Phase change composite bimorphs [PDF]

, 2018
A bilayer composite thin-film beam structure is described. The structure incorporates a bulk phase change material as small inclusions in one layer of a bimorph.
Blonder, Greg
core  

CD47 promotes mitogen‐activated protein kinase and epithelial‐to‐mesenchymal transition molecular programs to drive prometastatic phenotypes in non‐small cell lung cancer

Molecular Oncology, EarlyView.
Beyond its role in immune evasion, this study identified that CD47 drives tumor‐intrinsic signaling in non‐small cell lung cancer (NSCLC). Transcriptomic profiling and functional studies revealed that CD47 regulates cell adhesion, migration, and metastasis through an ERK–EMT signaling axis.
Asa P.Y. Lau, Lilian G. Zhai, Ryunosuke Hoshi, Zackary Rousseau, Abraam Zakhary, Yin Fang Wu, Rola M. Saleeb, Heyu Ni, Kelsie L. Thu   +8 more
wiley   +1 more source

Experimental Evaluation of a Paraffin as Phase Change Material for Thermal Energy Storage in Laboratory Equipment and in a Shell-and-Tube Heat Exchanger

Applied Sciences, 2016
The thermal behavior of a commercial paraffin with a melting temperature of 58 °C is analyzed as a phase change material (PCM) candidate for industrial waste heat recovery and domestic hot water applications.
Jaume Gasia, Laia Miró, Alvaro de Gracia, Camila Barreneche, Luisa F. Cabeza   +4 more
doaj   +1 more source

Degeneration of postovulatory follicles in the Iberian sardine Sardina pilchardus: structural changes and factors affecting resorption [PDF]

, 2007
Inaccuracy in the aging of postovulatory follicles (POFs) and in estimating the effect of temperature on the resorption rate of POFs may introduce bias in the determination of the daily spawning age classes with the daily egg production method (DEPM). To
Ganias , Konstantinas, Nunes, Cristina, Stratoudakis, Yorgos   +2 more
core  

Study of Cu2O Particle Morphology on Microwave Field Enhancement

, 2018
The dielectric enhancement and modulation of a cuprous oxide (Cu2O) microwave-active catalyst material is investigated from an experimental and computational point of view.
Houlihan, Nora, Musho, Terence, Sabolsky, Edward M., Shekhawat, Dushyant, Wildfire, Christina   +4 more
core   +1 more source