Results 141 to 150 of about 109,391 (304)

Tissue Volume and Section Area Changes of Paraffin and Methacrylate Embedded Testicular Sections: An Unbiased Design Study

Image Analysis and Stereology
For stereological estimates of structures in an organ such as total number (particles), length or surface area, the tissue change after processing (usually embedding of tissue blocks, sectioning of embedded blocks, and mounting and staining of sections)
Yang Guo, Yu Xiang, Dan Wang, Zheng-Wei Yang   +3 more
doaj   +1 more source

Characterization of an Injectable Poly(vinyl alcohol)‐gelatin Hydrogel for Growth Factor Delivery in an Orthopedic Application

Advanced Healthcare Materials, EarlyView.
This work introduces photo‐crosslinkable tyraminated poly(vinyl alcohol)‐gelatin (PVA‐GT) hydrogels as tunable injectable platforms for tissue engineering and growth factor delivery applications. This schematic illustrates the two developed hydrogel formulations and the experimental workflow used to evaluate their physico‐chemical properties in vitro ...
Alessia Longoni, Gretel S. Major, Sam Arnold, Samuel Tomkins, Eugenia Spessot, Scott Loeffler, Kieran Lau, Richard Tan, Jessica Harte, Roslyn Kemp, Tess Reynolds, Jelena Rnjak‐Kovacina, Gary J. Hooper, Tim B. F. Woodfield, David C. Kieser, Khoon S. Lim   +15 more
wiley   +1 more source

A Personalized, 3D Printed Polymeric Device for the Prevention of Post‐Myocardial Infarction Cardiac Remodeling

Advanced Healthcare Materials, EarlyView.
Myocardial infarction often leads to pathological remodelling and ventricular dilatation, key features of HFrEF. This study introduces a personalized, 3D‐printed cardiac restraint device (CARD) printed using rationally designed inks displaying the requested printability and mechanical properties.
Nicola Mansour, Daniel Cohn, Ishita Sarkar, Raja Alamore, Kareem Abd Rbo, Offer Amir, Dean Nachman   +6 more
wiley   +1 more source

Flash Assembloids: A Rapid Biofabrication of a Platform for Modeling Early Glioblastoma Invasion at the Glioblastoma–Brain Organoid Interfaces

Advanced Healthcare Materials, EarlyView.
This study presents a bioengineered assembloid (ASM) system combining glioblastoma (GBM) cells in oxidized alginate (OA) microgels with dorsal organoids (DOs). This model simulates brain tumor‐host interactions, revealing enhanced GBM invasion, altered gene expression, and aggressive infiltration patterns, demonstrating ASM as a valuable platform for ...
Chao Liang, Henry Robert Howard, Shihui Chen, Won‐Young Choi, Summer Cao, Arthur Chien, Kevin Zou, Michael Kassiou, Fabien Delerue, Ho Sang Jung, Yeonju Park, Young Mee Jung, Yong‐Dae Kwon, Karrie M. Kiang, Gilberto Ka‐Kit Leung, Ryohichi Sugimura, Ann‐Na Cho, Sang Jin Lee   +17 more
wiley   +1 more source

Paraffin Embedded Tissue [PDF]

, 2020
openaire   +1 more source

Sprayable Polymer Blends With Short‐Chain Surface Segregation for Preventing Postoperative Abdominal Adhesions

Advanced Healthcare Materials, EarlyView.
Adhesions’ high occurrence rates and high morbidity render them a critical challenge to be addressed. Current prevention methods, such as physical barriers, have many limitations, resulting in inconsistent safety and efficacy. This study demonstrates the potential for sprayable polymeric materials as an adhesion barrier.
Robert J. Morris III, Tejaswi Nori, Alex I. Halpern, Hannah LaPadula, Arthur V. Cresce, Sarah L. Wright, Anthony D. Sandler, Peter Kofinas   +7 more
wiley   +1 more source

Computer-aided techniques for Chromogenic Immunohistochemistry: Status and Directions [PDF]

, 2012
Al-Kofahi, Al-Kofahi, Baggett, Beck, Bogen, Borad, Boykov, Brennan, Brey, Brgmann, Canny, Cheng, Choudhury, Cooper, Cregger, Cross, Cualing, De Solorzano, Demir, Di Cataldo, Di Cataldo, Diaz, Dickinson, DiVito, Dobson, Elisa Ficarra, Elmoataz, Enrico Macii, Ficarra, Ficarra, Ficarra, Flowers, Fuchs, Garrido, Gilbert, Goldstein, Gudla, Gurcan, Gustavson, Hai-Shan Wu, Hama, Han, Hanna, He, Huang, Ingle, Jacob, Kim, Kong, Kurosumi, Lacroix-Triki, Landini, Lehr, Leong, Loos, Luck, Madabhushi, Makretsov, Malpica, Marttila, Masmoudi, Mccullough, Moffitt, Moon, Mueller, Mukherjee, Otsu, Petushi, Pietrini, Queschi, Ramos-Vara, Riera, Roerdink, Rojo, Ruifrok, Santa Di Cataldo, Scholzen, Sharpe, Shi, Shi, Slodkowska, Sompuram, Sun, Taneja, Taylor, Taylor, Theodosiou, Thiran, Tuominen, Umemura, Vonesch, Wang, Ward, Wolff, Woolley, Yang, Zacharaki, Zanella   +97 more
core   +1 more source

Deciphering the Role of Cancer Stem Cells in Breast Cancer Brain Colonization Using a Novel Patient‐Derived Model

Advanced Healthcare Materials, EarlyView.
This study shows that stem‐like cells isolated from breast cancer brain metastases drive the spread and growth of tumors in the brain. Among them, a highly adhesive subgroup initiates metastasis and resists many drugs. By closely reflecting patient tumors, these models help identify new targets and improve the development of effective treatments ...
Stefania Faletti, Cristina Richichi, Daniela Osti, Elena Ceccacci, Giovanni Bertalot, Camilla Cerutti, Giuseppina Giardina, Adriana Marinaro, Brunella Costanza, Valentina Gambino, Elena Zaccheroni, Daniela Tosoni, Maria G. Filippone, Marcello Del Corvo, Yinxiu Zhan, Teresa Gravina, Davide Corà, Monica Patanè, Bianca Pollo, Maria Giovanna Jodice, Salvatore Pece, Babette B. Weksler, Ignacio A. Romero, Pierre‐Olivier Couraud, Elisabetta Munzone, Massimiliano Del Bene, Francesco DiMeco, Giuliana Pelicci   +27 more
wiley   +1 more source

Extracellular Vesicles Modulation by an Adiponectin Receptor Agonist Provides Cardioprotection for Myocardial Ischemic Injury

Advanced Healthcare Materials, EarlyView.
This study demonstrates that ALY688, a drug mimicking the heart‐protective hormone adiponectin, reduces myocardial ischemia injury. ALY688 increases the production of extracellular vesicles, which carry protective cargo including adiponectin itself.
Jialing Tang, Wing Yan Chung, Serena M. Pulente, Yubin Lei, Khang Nguyen, Eddie Tam, Nadya M. Morrow, Ilka Lorenzen‐Schmidt, Fengxia Xiao, Augusto Zani, Dylan Burger, Hye Kyoung Sung, Erin E. Mulvihill, Gary Sweeney   +13 more
wiley   +1 more source

Paraffin Embedding and Thin Sectioning of Microbial Colony Biofilms for Microscopic Analysis. [PDF]

J Vis Exp, 2018
Cornell WC, Morgan CJ, Koyama L, Sakhtah H, Mansfield JH, Dietrich LEP.   +5 more
europepmc   +1 more source