Results 121 to 130 of about 48,067 (261)

G3BP1 Succinylation at K413 is Critical for Cardiac Function by Modulating PI3K‐AKT‐mTOR Signal Axis

Advanced Science, EarlyView.
Schematic illustrating the impact of G3BP1 succinylation at K413 on cardiac function. In the healthy human heart, G3BP1 succinylation maintains homeostatic mTOR signaling. In patients with dilated cardiomyopathy (DCM) and heart failure (HF), G3BP1 de‐succinylation induces RagA expression and disrupts the binding of the TSC1/2 complex, leading to the ...
Yuan Zhang, Cancan Yao, Yan Chen, Ke Cai, Zhouping Lu, Boxuan Wu, Kun Yu, Yan Shi, Jianyuan Zhao, Xiangyu Zhou   +9 more
wiley   +1 more source

Experimental study of solar air heater performance with evacuated tubes connected in series and involving nano-copper oxide/paraffin wax as thermal storage enhancer. [PDF]

Environ Sci Pollut Res Int, 2023
Elbrashy A, Aboutaleb F, El-Fakharany M, Essa FA.   +3 more
europepmc   +1 more source

Icariin Enhances the Enzymatic Activity of N‐acetylgalactosaminidase to Augment Akkermansia Abundance in Gut Microbiota for Improved PD‐1 Blockade Efficacy in Tumor Suppression

Advanced Science, EarlyView.
Icariin promoted the growth of Akk by enhancing the activity of N‐acetylgalactosaminidase (Amuc_0920), which enhanced mucin utilization and provided a favorable nutrient environment for bacterial growth. This icariin‐mediated enrichment of Akk further reshaped the tumor microenvironment and promoted CD8+ T cell infiltration, ultimately synergizing with
Shuangying Qiao, Liu Yang, Haibang Hao, Qiuxia Ding, Feng Ding, Zheng Chen, Jinfang Zhang, Yun He, Meng Li, Jun Xu, Chao Wang, Aiping Lu, Fangfei Li   +12 more
wiley   +1 more source

Control of the Hardness of the Oil-Wax Gel by Mixing of Normal Paraffin Wax and the Branched Paraffin Wax

Journal of the Japan Society of Colour Material, 2003
Masashi SHIBATA, Takeo IMAI, Yasushi ITOH, Genichi NAKAMURA, Koichi NAKAMURA, Hitoshi HOSOKAWA   +5 more
openaire   +2 more sources

HNRNPU K181 Lactylation Drives Cervical Cancer Growth by Upregulating PHGDH and Reprogramming Serine Metabolism

Advanced Science, EarlyView.
Lactate in cervical cancer induces HNRNPU K181 lactylation, opposed by NAA50‐mediated acetylation and suppressed by Pazopanib. This lactylation enhances HNRNPU binding to PHGDH pre‐mRNA exon 1, maintaining exon 1‐containing transcripts and mRNA stability, thereby activating serine metabolism.
Chang Zhang, Qingfei Meng, Hui Jiao, Huixin Liu, Xiangchao Wang, Honglan Zhou, Yishu Wang   +6 more
wiley   +1 more source

Enhancing Gypsum Plaster with Encapsulated Fischer-Tropsch Paraffin Wax as a Phase-Change Additive for Broad-Range Thermal Energy Storage. [PDF]

Polymers (Basel)
Voronin D, Smirnova E, Demikhova N, Sayfutdinova A, Kopitsyn D, Fakhrullin R, Vinokurov V, Stavitskaya A.   +7 more
europepmc   +1 more source

TSPYL5 Promotes Triple‐Negative Breast Cancer Metastasis by Antagonizing USP10‐Mediated PTEN Stabilization to Unleash a ZEB1‐Dependent EMT Program

Advanced Science, EarlyView.
The hyperactivation of PI3K/AKT signaling in PTEN wild‐type triple‐negative breast cancer represents a clinical paradox. We delineate a novel post‐translational regulatory axis wherein the oncogene TSPYL5 competitively antagonizes the deubiquitinase USP10.
Jiaying Shi, Ming Yi, Shengyu Xie, Zhaokun Wang, Xinyue Zhang, Yangwei Zhang, Rui Tang, Yuan Yang, Yunqiang Liu   +8 more
wiley   +1 more source

Sustainable Imidazolines Derived from Waste Cooking Oil for Corrosion and Paraffin Wax Inhibition in Petroleum Industry. [PDF]

ACS Omega
Edlabadkar VA, Rashidi Nodeh H, Khadka P, Sadatfaraji H, Nwobodo I, Reyes S, Rivera C, Lopez J, Dugat E, Turaga VR, Disney J.   +10 more
europepmc   +1 more source

PSMA8‐Containing 20S Proteasome Regulates Spermiogenesis and Male Fertility

Advanced Science, EarlyView.
PSMA8 assembles s20S proteasome that degrades specific substrates in elongating spermatids. Degradation of s20S‐substrates activates translation of FXR1‐target mRNAs, which are essential for mitochondrial sheath formation and sperm morphogenesis.
Huiwen Cao, Qianting Zhang, Wei Xu, Anxuan Fang, Haomang Xu, Cheng Qiu, Lugeng He, Chao Yu   +7 more
wiley   +1 more source

Within-Patient, Quasi-Experimental Clinical Trial to Assess the Immediate Effects of Paraffin Wax on Adult, Post-Burn Hypertrophic Scar. [PDF]

J Burn Care Res
Bellali YA, Jetté S, Delisle M, Pinard-LaRoche A, Edger-Lacoursière Z, Nedelec B.   +5 more
europepmc   +1 more source