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Risk Stratification on Pheochromocytoma and Paraganglioma from Laboratory and Clinical Medicine [PDF]
Pheochromocytoma (PCC) and sympathetic paraganglioma (PGL) are rare neuroendocrine tumors characterized by catecholamine production in the adrenal medulla and extra-adrenal paraganglia.
Kimura Noriko+3 more
core +3 more sources
Pheochromocytomas and paragangliomas [PDF]
Purpose of review Great progress has been made in understanding the genetic and molecular basis of pheochromocytoma and paragangliomas (PPGLs). This review highlights the new standards in the diagnosis and management of pediatric PPGLs. Recent findings The vast majority of pediatric
Yen, Kevin, Lodish, Maya
openaire +4 more sources
Personalized Management of Pheochromocytoma and Paraganglioma
Pheochromocytomas/paragangliomas are characterized by a unique molecular landscape that allows their assignment to clusters based on underlying genetic alterations.
S. Nölting+8 more
semanticscholar +1 more source
New Insights on the Genetics of Pheochromocytoma and Paraganglioma and Its Clinical Implications
Simple Summary Pheochromocytoma and paraganglioma (together PPGL) are rare neuroendocrine tumors that arise from chromaffin tissue and produce catecholamines.
S. Jhawar+9 more
semanticscholar +1 more source
AbstractParagangliomas are rare tumors of the neuroendocrine system that form near certain blood vessels (paraaortic and carotid) and nerves, often presenting heterogeneous parenchyma and displaying strong contrast enhancement on computed tomography. Underdiagnosis and misdiagnosis of this tumor are suspected as they can be silent, of small size, or ...
Romeo Thierry Yehouenou Tessi+3 more
openaire +3 more sources
Paragangliomas are rare tumours of the autonomic nervous system and occur in sporadic and hereditary forms. They are usually benign and have a low mortality. However, they cause significant morbidity related to their mass effect. Genetic predisposition can occur within the familial tumour syndromes multiple endocrine neoplasia type 2 (MEN 2), von ...
Jwm Hoppener+4 more
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Imaging of Pheochromocytoma and Paraganglioma
Imaging plays a critical role in the management of pheochromocytomas and paragangliomas and often guides treatment. The discovery of susceptibility genes associated with these tumors has led to better understanding of clinical and imaging phenotypes ...
J. Carrasquillo+6 more
semanticscholar +1 more source
Sir, Paragangliomas are rare tumors originating from paraganglionic tissue that extends from the skull base to the pelvic diaphragm. Although they can be asymptomatic, they can also cause symptoms by secreting catecholamines or with local expansion. They can also be the component of many hereditary diseases.
Kilitçi, Asuman+2 more
openaire +4 more sources
Targeted radionuclide therapies (TRT) using 131I-metaiodobenzylguanidine (131I-MIBG) and peptide receptor radionuclide therapy (177Lu or 90Y) represent several of the therapeutic options in the management of metastatic/inoperable pheochromocytoma ...
Abhishek Jha+24 more
semanticscholar +1 more source
Teaching Point: A submucosal bladder wall lesion with high signal on T2-weighted MRI warrants blood and urine analysis to rule out a paraganglioma.
Degrieck, Bert+2 more
openaire +5 more sources