Results 81 to 90 of about 34,897 (270)
Risk Stratification on Pheochromocytoma and Paraganglioma from Laboratory and Clinical Medicine [PDF]
Pheochromocytoma (PCC) and sympathetic paraganglioma (PGL) are rare neuroendocrine tumors characterized by catecholamine production in the adrenal medulla and extra-adrenal paraganglia.
Kimura Noriko+3 more
core +2 more sources
A 57-year-old woman was admitted with lower abdominal pain and bloody bowel discharge. She was diagnosed with rectal tumor by colonoscopy, and a biopsy was performed. Surgery was performed, resulting in a diagnosis of rectal paraganglioma. Since recurrence was confirmed three years later, reoperation was done, and chemotherapy with cyclophosphamide ...
Koichiro Kusumoto+6 more
openaire +4 more sources
Paraganglioma gangliocítico duodenal [PDF]
We present a case of a 42-year-old man with abdominal pain, obstructive jaundice and a mass in the second portion of the duodenum, near the papillary region. The patient was operated and the histological study of the specimen returned duodenal gangliocytic paraganglioma (a rare submucosal benign tumor of the duodenum).
Prieto, C.+5 more
openaire +9 more sources
ABSTRACT Objective Managing gastrointestinal symptoms in patients with phaeochromocytoma and paraganglioma (PPGL) is challenging due to the risk of catecholaminergic crisis with many commonly prescribed medications, especially in functional tumours.
Monica Majumder+5 more
wiley +1 more source
Functional paraganglioma of the bladder: Both radiographic‐negative and laboratory‐negative case
Introduction Paraganglioma has been determined to be an extra‐adrenal pheochromocytoma. Paraganglioma of the bladder is a rare entity, accounting for 0.06% of all bladder tumors.
Rumiko Sugimura+9 more
doaj +1 more source
Gangliocytic paraganglioma: case report and review of the literature [PDF]
Gangliocytic paraganglioma is a rare tumor, which occurs nearly exclusively in the second portion of the duodenum. Generally, this tumor has a benign clinical course, although rarely, it may recur or metastasize to regional lymph nodes.
Galler, Avi+2 more
core +2 more sources
Genetic Testing Referral Rates for Pheochromocytoma and Paraganglioma in an Academic Tertiary Centre
ABSTRACT Background Clinical guidelines recommend genetic counselling for all patients with pheochromocytoma or paraganglioma (PPGL). Barriers to accessing genetics evaluation are incompletely understood. The objective of this study was to identify individual‐ and provider‐level barriers to genetic testing.
Brian Ruhle+8 more
wiley +1 more source
Choroidal Paraganglioma with Metastases to the Fellow Eye
Purpose: To report a case of a paraganglioma in the right eye with metastatic disease in the fellow eye 3 years later. Methods: A 70-year-old man presented with a painful amblyopic right eye; rubeosis iridis and a large choroidal tumor were found.
Rita Van Ginderdeuren+2 more
doaj +1 more source
PI5P4K inhibitors: promising opportunities and challenges
Developing inhibitors is like climbing a steep, challenging mountain. PI5P4K inhibitors hold significant promise for the treatment of cancer, immune disorders, and neurological diseases. However, the path to success is fraught with hurdles, and researchers are therefore required to apply their expertise to overcome critical “checkpoints.” While some ...
Koh Takeuchi+16 more
wiley +1 more source
A genome‐wide CRISPR‐Cas9‐based genetic screen in cisplatin‐resistant NSCLC cells revealed 63 potential candidate genes for overcoming cisplatin resistance, including GPR89A. GPR89A, localised in the Golgi, modulates voltage‐gated anion channel activity and is involved in intracellular pH reduction.
Hale Guler Kara+9 more
wiley +1 more source