Results 21 to 30 of about 62,313 (218)

Corrigendum to: "Linear time algorithm to cover and hit a set of line segments optimally by two axis-parallel squares", Theoretical Computer Science 769 (2019) 63--74

open access: yesCoRR, 2019
In the paper "Linear time algorithm to cover and hit a set of line segments optimally by two axis-parallel squares", TCS Volume 769 (2019), pages 63--74, the LHIT problem is proposed as follows: For a given set of non-intersecting line segments ${\cal L} = \{\ell_1, \ell_2, \ldots, \ell_n\}$ in $I\!\!R^2$, compute two axis-parallel congruent squares ${\
Sanjib Sadhu   +4 more
openaire   +2 more sources

Ovarian Sex Cord Stromal Tumors in Children and Adolescents—The European Standard Clinical Practice Recommendations

open access: yesPediatric Blood &Cancer, EarlyView.
ABSTRACT As part of the European Cooperative Study Group for Paediatric Rare Tumours initiative, we developed standard clinical practice guidelines for ovarian sex cord stromal tumors, based on comprehensive national and international cohort analyses, literature review, and a final expert consensus conference.
Dominik T. Schneider   +15 more
wiley   +1 more source

Association Between Individualized Education for Kidney Replacement Therapy Modality Selection and Peritoneal Dialysis Initiation: A Cross‐Sectional Study

open access: yesTherapeutic Apheresis and Dialysis, EarlyView.
ABSTRACT Introduction Peritoneal dialysis (PD) is an established home‐based kidney replacement therapy (KRT), but its uptake remains low in Japan. We evaluated whether individualized education in a dedicated outpatient clinic was associated with the initiation of PD.
Yasuko Ito   +7 more
wiley   +1 more source

Spatiotemporal and quantitative analyses of phosphoinositides – fluorescent probe—and mass spectrometry‐based approaches

open access: yesFEBS Letters, EarlyView.
Fluorescent probes allow dynamic visualization of phosphoinositides in living cells (left), whereas mass spectrometry provides high‐sensitivity, isomer‐resolved quantitation (right). Their synergistic use captures complementary aspects of lipid signaling. This review illustrates how these approaches reveal the spatiotemporal regulation and quantitative
Hiroaki Kajiho   +3 more
wiley   +1 more source

MOLOCH computer code for molecular-dynamics simulation of processes in condensed matter

open access: yesEPJ Web of Conferences, 2011
Theoretical and experimental investigation into properties of condensed matter is one of the mainstreams in RFNC-VNIITF scientific activity. The method of molecular dynamics (MD) is an innovative method of theoretical materials science.
Derbenev I.V.   +4 more
doaj   +1 more source

Structural insights into an engineered feruloyl esterase with improved MHET degrading properties

open access: yesFEBS Letters, EarlyView.
A feruloyl esterase was engineered to mimic key features of MHETase, enhancing the degradation of PET oligomers. Structural and computational analysis reveal how a point mutation stabilizes the active site and reshapes the binding cleft, expading substrate scope.
Panagiota Karampa   +5 more
wiley   +1 more source

Efficient utilization of multi-core processors and many-core co-processors on supercomputer beacon for scalable geocomputation and geo-simulation over big earth data

open access: yesBig Earth Data, 2018
Digital earth science data originated from sensors aboard satellites and platforms such as airplane, UAV, and mobile systems are increasingly available with high spectral, spatial, vertical, and temporal resolution data.
Chenggang Lai, Xuan Shi, Miaoqing Huang
doaj   +1 more source

Input-aware Generalized Matrix-Vector Product Algorithm for Adaptative PerformanceOptimization of Hygon DCU [PDF]

open access: yesJisuanji kexue
GEMV(generalized matrix-vector multiplication function) is the core component of BLAS(basic linear algebra subroutine) algorithm library,which is widely used in the fields of computer science,engineering computation and mathematical computation.Currently,
LI Qing, JIA Haipeng, ZHANG Yunquan, ZHANG Sijia
doaj   +1 more source

Structural insights and therapeutic targets in Acinetobacter baumannii capsule biosynthesis

open access: yesFEBS Letters, EarlyView.
Hypervirulent KL49 A. baumannii's capsular polysaccharide contains the nonulosonic acid 8‐epi‐Leg5,7Ac2, synthesized by epimerization via ElaA, ElaB, and ElaC. Crystal structures of ElaA, ElaB, and ElaC reveal their role in CMP‐Leg5,7Ac2 synthesis and regioselective C8 epimerization.
Woo Cheol Lee   +7 more
wiley   +1 more source

The role of miR‐335‐5p in the redifferentiation of BRAF p.V600E thyroid cancers

open access: yesMolecular Oncology, EarlyView.
The BRAF p.V600E mutation promotes thyroid cancer dedifferentiation and radioiodine resistance. Using a network approach, we identified miR‐335‐5p as a key regulator of BRAF‐mutated thyroid tumors. Restoring miR‐335‐5p increased thyroid‐specific gene expression and iodine uptake in cells and organoids.
Valeria Pecce   +11 more
wiley   +1 more source

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