Leveraging transformer-based artificial intelligence for enhanced anesthetic decision-making in orthopedic surgery. [PDF]
Mao Y +5 more
europepmc +1 more source
ABSTRACT Nitro‐fatty acids (NO2‐FAs) are potent electrophiles that react with nucleophilic residues in proteins (cysteines, histidines and lysines) via a process known as nitroalkylation. This reversible post‐translational modification (PTM) functions as a selective signalling mechanism by modulating the structure, transport, and catalysis of target ...
Lorena Aranda‐Caño +9 more
wiley +1 more source
Omega deoxyribonucleic acid cryptography key-based authentication. [PDF]
Chuah CW, Tey J, Mohamad KM.
europepmc +1 more source
ABSTRACT Cryptic marine species complexes with plastic morphology, shallow divergence, and broad distributions are among the hardest taxonomic problems in zoology. The Ostrea stentina complex, reported across the Atlantic, Mediterranean, and Indo‐Pacific, is a striking example. We present the first topotype‐anchored integrative revision of this complex,
Matteo Garzia +3 more
wiley +1 more source
Regional, altitudinal, and age-specific heterogeneity of bronchiolitis hospitalization seasonality in Ecuador, 2007-2024, and implications for RSV immunoprophylaxis timing. [PDF]
Angamarca-Iguago J +6 more
europepmc +1 more source
Sound offset responses become highly informative in the auditory cortex
Abstract figure legend Using large datasets of neural responses to diverse sounds recorded across four stages of the mouse auditory system (depicted and colour‐coded on the left), offset responses occurring after the termination of each sound (time window indicated by the orange shaded area superimposed with activity traces) were characterized and it ...
Charly Lamothe +3 more
wiley +1 more source
A New Challenge to Species Delimitation: Remarkable Genomic and Ecological Diversity in the Butterfly Melitaea diamina. [PDF]
Spilani L +8 more
europepmc +1 more source
Abstract figure legend Sounds of different frequencies elicit spatially distinct patterns of neural activity within the inferior colliculus aligned to the tonotopic organization of afferent projections. Sound‐evoked neural responses can be visualized in awake mice that express fluorescent Ca2+ sensors.
Patrick D. Parker +2 more
wiley +1 more source
Enhancing k<sub>cat</sub> prediction through residue-aware attention mechanism and pre-trained representations. [PDF]
Cai Y +6 more
europepmc +1 more source
Evaluating Large‐Language Models in Bioinformatics Applications
This work systematically evaluates advanced large language models across six representative bioinformatics tasks, from drug–drug interaction prediction and molecular optimization to single‐cell annotation and computational biology problem solving. The benchmark quantifies both their promise and limitations, offering practical guidance for prompt design,
Hengchuang Yin +9 more
wiley +1 more source

