Results 151 to 160 of about 1,578 (183)

Conformational diversity in poly‐HAMP arrays and its implications for signal transduction

open access: yesProtein Science, Volume 35, Issue 9, September 2026.
Abstract Prokaryotic transmembrane receptors are built around a helical coiled‐coil backbone, with sensory, modulatory, and effector domains arranged along its length. The modulatory HAMP domain forms a parallel four‐helix coiled coil integrated into this backbone, typically connecting transmembrane segments with downstream cytosolic domains.
Murray Coles   +8 more
wiley   +1 more source

Performance and Biases of the LENA and ACLEW Algorithms in Analyzing Language Environments in Down, Fragile X, Angelman Syndromes, and Populations at Elevated Likelihood for Autism

open access: yesDevelopmental Science, Volume 29, Issue 5, September 2026.
ABSTRACT Wearable recorders are used in research and clinical practice to collect and measure children's vocalizations and the language environment in which they occur. Recordings generate vast amounts of audio, making manual analysis impractical and requiring automated processing.
Marvin Lavechin   +3 more
wiley   +1 more source

Membrane Complexity and Phase Behavior Dictate the Stability of Membrane‐Inserted Aβ42 Hexamers

open access: yesChemPhysChem, Volume 27, Issue 16, 27 August 2026.
Neuronal membrane order and the specific interplay of constituent lipids modulate the structural stability of Aβ(1–42) hexamers. This lipid environment facilitates the stabilization of a transmembrane β‐barrel conformation, providing a molecular basis for understanding how membrane composition influences the formation of stable amyloid pores in ...
Bastian Ferdinand Bundschuh   +3 more
wiley   +1 more source

High-throughput identification of bacterial β-glucuronidase inhibitors using machine learning. [PDF]

open access: yesGut Microbes
Zhang B   +6 more
europepmc   +1 more source

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