Results 41 to 50 of about 1,547,357 (293)

Problems of the Russian economy in 2023–2024: the catch–up development trap, parallel imports, distribution of national income and development of competition

open access: yesПутеводитель предпринимателя
The authors of the article focused on the current problems of the Russian economy in 2023–2024, such as: import substitution and the catch–up development trap, parallel import, insufficiently efficient distribution of national income and the need to ...
S. L. Sazanova, S. P. Rogozhin
doaj   +1 more source

Membrane composition and thermodynamic identity as boundaries of life for synthetic cell research

open access: yesFEBS Letters, EarlyView.
What makes a cell a cell? The boundary of a living cell is not just a wall. Read as a Markov blanket, the membrane separates internal from external states, generating identity and non‐equilibrium order. Can this identity be rebuilt from scratch in a synthetic cell?
Caterina Presutti, Bert Poolman
wiley   +1 more source

A specific role for importin-5 and NASP in the import and nuclear hand-off of monomeric H3

open access: yeseLife, 2022
Core histones package chromosomal DNA and regulate genomic transactions, with their nuclear import and deposition involving importin-β proteins and a dedicated repertoire of histone chaperones. Previously, a histone H3-H4 dimer has been isolated bound to
Alonso Javier Pardal   +1 more
doaj   +1 more source

Space exploration using parallel orbits:A study in parallel symbolic computing [PDF]

open access: yes, 2013
Orbit enumerations represent an important class of mathematical algorithms which is widely used in computational discrete mathematics. In this paper, we present a new shared-memory implementation of a generic Orbit skeleton in the GAP computer algebra ...
Brown, Christopher Mark   +11 more
core   +1 more source

MagmaFlow: A desktop platform for artificial intelligence‐driven expression analysis

open access: yesFEBS Open Bio, EarlyView.
MagmaFlow is a free, no‐code platform for gene expression analysis. It generates interactive volcano plots, links genes to literature, pathways, and diseases, prioritizes candidates using millions of publications, identifies affected biological processes, builds network diagrams, and exports publication‐ready figures and reports for macOS and Windows ...
Carlos E. Buss   +7 more
wiley   +1 more source

Structural studies and functional engineering of NanX: an anhydro‐sialic acid transporter from Escherichia coli

open access: yesFEBS Open Bio, EarlyView.
Biophysical characterisation shows that NanX, a membrane transport protein from the major facilitator superfamily (MFS), forms both monomers and dimers after purification. AlphaFold modelling and substrate docking provide information on residues likely involved in substrate recognition for NanX and another MFS member, NanT.
Michael C. Newton‐Vesty   +13 more
wiley   +1 more source

Salmonella enterica serovar typhi limits the potency of typhoid toxin and ADP‐ribosylating toxin AB to establish a persistent infection

open access: yesFEBS Open Bio, EarlyView.
The two catalytic subunits of typhoid toxin dissociate from the holotoxin in the ER of an intoxicated cell, but only CdtB exits the ER to generate immunosuppressive effects. PltA is retained in the ER and sequestered from its cytosolic target, thus allowing the anti‐inflammatory effects of CdtB to promote intestinal colonization.
Maria C. Zabala‐Rodriguez   +4 more
wiley   +1 more source

MedFDTD: A Parallel and Open-Source Cross-Platform Framework for Bioelectromagnetics Field Simulation

open access: yesIEEE Access, 2018
MedFDTD, a new parallel and open-source cross-platform framework for bioelectromagnetics research, has been developed by solving Maxwell's equations using the finite-difference time-domain method.
Wang Meng, Liu Qian
doaj   +1 more source

Extending Graph-Based Process Discovery for Hierarchical Block Detection and Incomplete Concurrent Relationship Handling

open access: yesIEEE Access, 2023
The flow of business process activities in an organization can run simply in the form of sequential or complex in the form of choice and parallel. In the discovery process, parallel conditions can be deduced from the concurrent flows between activities ...
Indra Waspada   +4 more
doaj   +1 more source

BCG vaccination potentiates oxidative phosphorylation in neonatal myeloid‐derived suppressor cells

open access: yesFEBS Open Bio, EarlyView.
BCG vaccination enhances oxidative phosphorylation in neonatal MDSCs, impairing their immunosuppressive function. It upregulates electron transport chain genes and mitochondrial activity, increasing ATP and oxygen consumption. Pharmacological OXPHOS inhibition partially restores suppressive capacity, confirming causality.
Yingying Chen, Hui Li
wiley   +1 more source

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