Results 51 to 60 of about 656,145 (300)
MATEC Web of Conferences, 2016 It is important for huge ship to find the ceramic/metal functional gradient thermal barrier coating materials. A parallel computation model is built for optimization design of three-dimensional ceramic/metal functionally gradient thermal barrier coating ...
Chen Zhao, Zhang Shesheng
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Simple and Robust Boolean Operations for Triangulated Surfaces
Mathematics, 2023 Boolean operations on geometric models are important in numerical simulation and serve as essential tools in the fields of computer-aided design and computer graphics. The accuracy of these operations is heavily influenced by finite precision arithmetic,
Meijun Zhou +3 more
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FEBS Letters, EarlyView.This perspective highlights emerging insights into how the circadian transcription factor CLOCK:BMAL1 regulates chromatin architecture, cooperates with other transcription factors, and coordinates enhancer dynamics. We propose an updated framework for how circadian transcription factors operate within dynamic and multifactorial chromatin landscapes ...
Xinyu Y. Nie, Jerome S. Menet
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First steps towards more numerical reproducibility*
ESAIM: Proceedings and Surveys, 2014 Questions whether numerical simulation is reproducible or not have been reported in several sensitive applications. Numerical reproducibility failure mainly comes from the finite precision of computer arithmetic.
Jézéquel Fabienne +2 more
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Integrating MPI-based numerical software into an advanced parallel computing environment [PDF]
Eleventh Euromicro Conference on Parallel, Distributed and Network-Based Processing, 2003. Proceedings., 2003 In this paper we present first experiences concerning the integration of MPI-based numerical software into an advanced programming environment for building parallel and distributed high-performance applications, which is under development in the context of Italian national research projects.
P. D’Ambra +3 more
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Disordered but rhythmic—the role of intrinsic protein disorder in eukaryotic circadian timing
FEBS Letters, EarlyView.Unstructured domains known as intrinsically disordered regions (IDRs) are present in nearly every part of the eukaryotic core circadian oscillator. IDRs enable many diverse inter‐ and intramolecular interactions that support clock function. IDR conformations are highly tunable by post‐translational modifications and environmental conditions, which ...
Emery T. Usher, Jacqueline F. Pelham
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A Computational Realization of a Semi-Lagrangian Method for Solving the Advection Equation
Journal of Applied Mathematics, 2014 A parallel implementation of a method of the semi-Lagrangian type for the advection equation on a hybrid architecture computation system is discussed. The difference scheme with variable stencil is constructed on the base of an integral equality between ...
Alexander Efremov +3 more
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Protein pyrophosphorylation by inositol pyrophosphates — detection, function, and regulation
FEBS Letters, EarlyView.Protein pyrophosphorylation is an unusual signaling mechanism that was discovered two decades ago. It can be driven by inositol pyrophosphate messengers and influences various cellular processes. Herein, we summarize the research progress and challenges of this field, covering pathways found to be regulated by this posttranslational modification as ...
Sarah Lampe +3 more
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Time after time – circadian clocks through the lens of oscillator theory
FEBS Letters, EarlyView.Oscillator theory bridges physics and circadian biology. Damped oscillators require external drivers, while limit cycles emerge from delayed feedback and nonlinearities. Coupling enables tissue‐level coherence, and entrainment aligns internal clocks with environmental cues.
Marta del Olmo +2 more
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The newfound relationship between extrachromosomal DNAs and excised signal circles
FEBS Letters, EarlyView.Extrachromosomal DNAs (ecDNAs) contribute to the progression of many human cancers. In addition, circular DNA by‐products of V(D)J recombination, excised signal circles (ESCs), have roles in cancer progression but have largely been overlooked. In this Review, we explore the roles of ecDNAs and ESCs in cancer development, and highlight why these ...
Dylan Casey, Zeqian Gao, Joan Boyes
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