Results 51 to 60 of about 28,321 (263)
Hyperosmotic stress induces PARP1‐mediated HPF1‐dependent mono(ADP‐ribosyl)ation
FEBS Letters, EarlyView.Sorbitol‐induced hyperosmotic stress rapidly induces reversible mono(ADP‐ribosyl)ation (MARylation) on PARP1 without the signs of genotoxic signaling. We show that PARP1 autoMARylation is HPF1 dependent and forms hydroxylamine‐resistant O‐glycosidic linkages.
Anna Georgina Kopasz +11 more
wiley +1 more source
An isoform of 14‐3‐3 protein regulates transbilayer lipid movement at the plasma membrane
FEBS Letters, EarlyView.Loss of 14‐3‐3ζ in CHO cells confers resistance to exogenous phosphatidylserine (PS) and impairs endocytosis‐independent inward flip‐flop of fluorescent PS at the plasma membrane. RNAi‐mediated knockdown reproduces this defect, while no additive effect is seen in ATP11C‐deficient cells.
Akiko Yamaji‐Hasegawa +3 more
wiley +1 more source
FEBS Letters, EarlyView.Embryo‐like structures (stembryos) are an innovative tool, but they are hindered by experimental variability and limited developmental potential. DNA methylation is crucial for mammalian development, but its status in stembryo models is poorly characterized.
Sara Canil +4 more
wiley +1 more source
An Improved Approach to the PageRank Problems
Journal of Applied Mathematics, 2013 We introduce a partition of the web pages particularly suited to the PageRank problems in which the web link graph has a nested block structure. Based on the partition of the web pages, dangling nodes, common nodes, and general nodes, the hyperlink ...
Yue Xie +3 more
doaj +1 more source
Modulation of Homer1 EVH1 domain internal dynamics by putative autism‐associated mutations
FEBS Letters, EarlyView.The putative autism‐associated M65I and S97L variants of the EVH1 domain of the postsynaptic scaffold protein Homer1 do not exhibit substantial changes in their overall structure or partner binding. Both of them, but especially the M65I variant, show altered internal dynamics relative to the wild‐type domain on the μs‐ms timescale, indicated by the ...
Fanni Farkas +6 more
wiley +1 more source
Applied SciencesCurrently, research on the lattice Boltzmann method mainly focuses on its numerical simulation and applications, and there is an increasing demand for large-scale simulations in practical scenarios.
Shunan Tao +4 more
doaj +1 more source
Nuclear Engineering and Technology, 2014 Scattering source calculations using conventional spherical harmonic expansion may require lots of computation time to treat full-coupled three-dimensional photon-electron transport in a highly anisotropic scattering medium where their scattering cross ...
JONG WOON KIM +2 more
doaj +1 more source
Cogent Engineering, 2020 This article considered the numerical simulation of multicomponent multiphase flow in porous media. The resulting system of nonlinear equations linearized by the Newton-Raphson method and solved with the iterative Generalized minimal residual method ...
Saltanbek T. Mukhambetzhanov +5 more
doaj +1 more source
Parallel real-time numerical computation: beyond speedup. III
Proceedings International Conference on Information Technology: Coding and Computing (Cat. No.PR00540), 2002 For pt. II see Technical Report No. 99-423, Dept. of Comput. and Inf. Sci., Queen's University, Kingston, Ontario, May 1999. Parallel computers can do more than simply speed up sequential computations. They are capable of finding solutions that are far better in quality than those obtained by sequential computers. This fact is demonstrated by analyzing
Akl, Selim G., Bruda, Stefan D.
openaire +2 more sources
FEBS Letters, EarlyView.An unexpected alternative interaction site for ethyl viologen was identified in formate dehydrogenase 1 from Methylorubrum extorquens. Combined mutagenesis, kinetic analysis, and docking revealed that aromatic residues near an iron–sulfur cluster enable flavin mononucleotide‐independent electron transfer, offering a framework for engineering improved ...
Eleni G. Poloniataki, Yong Hwan Kim
wiley +1 more source