Results 161 to 170 of about 2,064,930 (283)

The Aging Blood: Cellular Origins, Circulating Drivers, and Therapeutic Potential

Aging and Cancer, EarlyView.
As a conduit linking all organs, the blood system both reflects and actively drives systemic aging. This review highlights how circulating pro‐aging and antiaging factors and age‐associated hematopoietic stem cell dysfunction contribute to immunosenescence and multi‐organ decline, positioning the hematopoietic system as a target for aging intervention.
Hanqing He, Jianwei Wang
wiley   +1 more source

Evaluating the contribution of parallel processing of color and shape in a conjunction search task. [PDF]

Sci Rep
Cui AY, Buetti S, Xu ZJ, Lleras A.
europepmc   +1 more source

Parallel processing of working memory and temporal information by distinct types of cortical projection neurons. [PDF]

Nat Commun, 2021
Bae JW, Jeong H, Yoon YJ, Bae CM, Lee H, Paik SB, Jung MW.   +6 more
europepmc   +1 more source

Natural Products as Geroprotective Modulators in Diabetic Nephropathy: A Mechanistic Framework Integrating Aging Hallmarks and the AMPK–SIRT1–Nrf2 Axis

Aging and Cancer, EarlyView.
Natural products target the aging kidney in diabetic nephropathy by restoring the AMPK–SIRT1–Nrf2 axis, reducing oxidative stress, inflammation, fibrosis, and cellular senescence while enhancing mitochondrial biogenesis and antioxidant defenses.
Sherif Hamidu, Latif Adams, Eunice Ampem‐Danso, Justice Kumi, Abigail Aning, Fatima Hamidu, Mustapha Abdul Mumin Mohammed, Ayuba Nii Darku Ankrah, Seth Kwabena Amponsah   +8 more
wiley   +1 more source

Morphological and Molecular Distinctions of Parallel Processing Streams Reveal Two Koniocellular Pathways in the Tree Shrew DLGN. [PDF]

eNeuro
Sciaccotta F, Kipcak A, Erisir A.
europepmc   +1 more source

Network Localization of Fatigue in Multiple Sclerosis

Annals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Background Fatigue is among the most common symptoms and one of the main factors determining the quality of life in multiple sclerosis (MS). However, the neurobiological mechanisms underlying fatigue are not fully understood. Here we studied lesion locations and their connections in individuals with MS, aiming to identify brain networks ...
Olli Likitalo, Jaakko Kungshamn, Albert Bellmunt‐Gil, Silvia Tommasin, Abhineet Ojha, Matias Viitala, Juho Aaltonen, Jyrki Lötjönen, Juha Koikkalainen, Pauli Ylikotila, Patrizia Pantano, Merja Soilu‐Hänninen, Juho Joutsa   +12 more
wiley   +1 more source

Molecular logic for cellular specializations that initiate the auditory parallel processing pathways. [PDF]

Nat Commun
Jing J, Hu M, Ngodup T, Ma Q, Lau SN, Ljungberg MC, McGinley MJ, Trussell LO, Jiang X.   +8 more
europepmc   +1 more source

Real‐World Investigation of Satralizumab in Patients With Neuromyelitis Optica Spectrum Disease

Annals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Objective Satralizumab, a monoclonal antibody targeting the interleukin‐6 receptor, has demonstrated efficacy in clinical trials for neuromyelitis optica spectrum disorder (NMOSD). However, its real‐world effectiveness and safety compared to conventional immunosuppressive therapies remain uncertain.
Li‐Tsung Lin, Hui‐An Lin, Sheng‐Feng Lin   +2 more
wiley   +1 more source

Parallel processing of past and future memories through reactivation and synaptic plasticity mechanisms during sleep. [PDF]

Nat Commun
Ghandour K, Haga T, Ohkawa N, Fung CCA, Nomoto M, Fayed MR, Asai H, Sato M, Fukai T, Inokuchi K.   +9 more
europepmc   +1 more source

Dual-Task Interference in a Simulated Driving Environment: Serial or Parallel Processing? [PDF]

Front Psychol, 2020
Abbas-Zadeh M, Hossein-Zadeh GA, Vaziri-Pashkam M.   +2 more
europepmc   +1 more source