Results 41 to 50 of about 19,549,248 (348)
Mapping the evolution of mitochondrial complex I through structural variation
FEBS Letters, EarlyView.Respiratory complex I (CI) is crucial for bioenergetic metabolism in many prokaryotes and eukaryotes. It is composed of a conserved set of core subunits and additional accessory subunits that vary depending on the organism. Here, we categorize CI subunits from available structures to map the evolution of CI across eukaryotes. Respiratory complex I (CI)
Dong‐Woo Shin +2 more
wiley +1 more source
Scientific Reports, 2021 Grading individual knee osteoarthritis (OA) features is a fine-grained knee OA severity assessment. Existing methods ignore following problems: (1) more accurately located knee joints benefit subsequent grades prediction; (2) they do not consider knee ...
Kang Wang +4 more
doaj +1 more source
Oxytocin: Parallel Processing in the Social Brain?
Journal of neuroendocrinology, 2015 Early studies attempting to disentangle the network complexity of the brain exploited the accessibility of sensory receptive fields to reveal circuits made up of synapses connected both in series and in parallel.
Gül Dölen
semanticscholar +1 more source
Reciprocal control of viral infection and phosphoinositide dynamics
FEBS Letters, EarlyView.Phosphoinositides, although scarce, regulate key cellular processes, including membrane dynamics and signaling. Viruses exploit these lipids to support their entry, replication, assembly, and egress. The central role of phosphoinositides in infection highlights phosphoinositide metabolism as a promising antiviral target.
Marie Déborah Bancilhon, Bruno Mesmin
wiley +1 more source
FEBS Letters, EarlyView.Fluorescent probes allow dynamic visualization of phosphoinositides in living cells (left), whereas mass spectrometry provides high‐sensitivity, isomer‐resolved quantitation (right). Their synergistic use captures complementary aspects of lipid signaling. This review illustrates how these approaches reveal the spatiotemporal regulation and quantitative
Hiroaki Kajiho +3 more
wiley +1 more source
A Cre‐dependent lentiviral vector for neuron subtype‐specific expression of large proteins
FEBS Letters, EarlyView.We designed a versatile and modular lentivector comprising a Cre‐dependent switch and self‐cleaving 2A peptide and tested it for co‐expression of GFP and a 2.8 kb gene of interest (GOI) in mouse cortical parvalbumin (PV+) interneurons and midbrain dopamine (TH+) neurons.
Weixuan Xue +6 more
wiley +1 more source
A Nonconvex Implementation of Sparse Subspace Clustering: Algorithm and Convergence Analysis
IEEE Access, 2020 Subspace clustering has been widely applied to detect meaningful clusters in high-dimensional data spaces. And the sparse subspace clustering (SSC) obtains superior clustering performance by solving a relaxed ℓ0-minimization problem with ℓ1-
Xiaoge Deng +3 more
doaj +1 more source
The Caenorhabditis elegans DPF‐3 and human DPP4 have tripeptidyl peptidase activity
FEBS Letters, EarlyView.The dipeptidyl peptidase IV (DPPIV) family comprises serine proteases classically defined by their ability to remove dipeptides from the N‐termini of substrates, a feature that gave the family its name. Here, we report the discovery of a previously unrecognized tripeptidyl peptidase activity in DPPIV family members from two different species.
Aditya Trivedi, Rajani Kanth Gudipati
wiley +1 more source
Another Robust NMF: Rethinking the Hyperbolic Tangent Function and Locality Constraint
IEEE Access, 2019 Non-negative matrix factorization (NMF) is a classical data analysis tool for clustering tasks. It usually considers the squared loss to measure the reconstruction error, thus it is sensitive to the presence of outliers. Looking into the literature, most
Xingyu Shen +4 more
doaj +1 more source
Frontiers in Energy Research, 2021 Scalable parallel algorithm for particle transport is one of the main application fields in high-performance computing. Discrete ordinate method (Sn) is one of the most popular deterministic numerical methods for solving particle transport equations.
Biao Li +7 more
doaj +1 more source