Results 41 to 50 of about 2,064,930 (283)

Adjunctive Therapeutic Plasma Exchange in Refractory Adult‐Onset Still's Disease Complicated by Secondary Macrophage Activation Syndrome: A Single‐Center Experience

Therapeutic Apheresis and Dialysis, EarlyView.
ABSTRACT Introduction Adult‐onset Still's disease (AOSD) complicated by macrophage activation syndrome (MAS) carries substantial mortality. The role of therapeutic plasma exchange (TPE) remains uncertain. Methods We retrospectively analyzed patients with AOSD‐MAS treated with TPE at a single‐center.
Masataka Ueda, Tomohiro Saito, Masahide Mizobuchi, Tomoki Shimomura, Saki Kawamori, Mitsuru Kawanishi, Natsuko Hattori, Jo Sugiyama, Satoshi Tsubata, Hanami Horiguchi, Kazuki Abe, Nao Iida, Yuki Kajio, Nao Oguro, Ryo Yanai, Hirokazu Honda   +15 more
wiley   +1 more source

Revealing the structure of land plant photosystem II: the journey from negative‐stain EM to cryo‐EM

FEBS Letters, EarlyView.
Advances in cryo‐EM have revealed the detailed structure of Photosystem II, a key protein complex driving photosynthesis. This review traces the journey from early low‐resolution images to high‐resolution models, highlighting how these discoveries deepen our understanding of light harvesting and energy conversion in plants.
Roman Kouřil
wiley   +1 more source

Mapping the evolution of mitochondrial complex I through structural variation

FEBS Letters, EarlyView.
Respiratory complex I (CI) is crucial for bioenergetic metabolism in many prokaryotes and eukaryotes. It is composed of a conserved set of core subunits and additional accessory subunits that vary depending on the organism. Here, we categorize CI subunits from available structures to map the evolution of CI across eukaryotes. Respiratory complex I (CI)
Dong‐Woo Shin, Tingting Chen, James A. Letts   +2 more
wiley   +1 more source

A Nonconvex Implementation of Sparse Subspace Clustering: Algorithm and Convergence Analysis

IEEE Access, 2020
Subspace clustering has been widely applied to detect meaningful clusters in high-dimensional data spaces. And the sparse subspace clustering (SSC) obtains superior clustering performance by solving a relaxed ℓ0-minimization problem with ℓ1-
Xiaoge Deng, Tao Sun, Peibing Du, Dongsheng Li   +3 more
doaj   +1 more source

Reciprocal control of viral infection and phosphoinositide dynamics

FEBS Letters, EarlyView.
Phosphoinositides, although scarce, regulate key cellular processes, including membrane dynamics and signaling. Viruses exploit these lipids to support their entry, replication, assembly, and egress. The central role of phosphoinositides in infection highlights phosphoinositide metabolism as a promising antiviral target.
Marie Déborah Bancilhon, Bruno Mesmin
wiley   +1 more source

Another Robust NMF: Rethinking the Hyperbolic Tangent Function and Locality Constraint

IEEE Access, 2019
Non-negative matrix factorization (NMF) is a classical data analysis tool for clustering tasks. It usually considers the squared loss to measure the reconstruction error, thus it is sensitive to the presence of outliers. Looking into the literature, most
Xingyu Shen, Xiang Zhang, Long Lan, Qing Liao, Zhigang Luo   +4 more
doaj   +1 more source

Large-Scale Heterogeneous Computing for 3D Deterministic Particle Transport on Tianhe-2A Supercomputer

Frontiers in Energy Research, 2021
Scalable parallel algorithm for particle transport is one of the main application fields in high-performance computing. Discrete ordinate method (Sn) is one of the most popular deterministic numerical methods for solving particle transport equations.
Biao Li, Biao Li, Jie Liu, Jie Liu, Xiaoxiong Zhu, Xiaoxiong Zhu, Shengjie Ding, Shengjie Ding   +7 more
doaj   +1 more source

Spatiotemporal and quantitative analyses of phosphoinositides – fluorescent probe—and mass spectrometry‐based approaches

FEBS Letters, EarlyView.
Fluorescent probes allow dynamic visualization of phosphoinositides in living cells (left), whereas mass spectrometry provides high‐sensitivity, isomer‐resolved quantitation (right). Their synergistic use captures complementary aspects of lipid signaling. This review illustrates how these approaches reveal the spatiotemporal regulation and quantitative
Hiroaki Kajiho, Shin Morioka, Junko Sasaki, Takehiko Sasaki   +3 more
wiley   +1 more source

Experimental Demonstration Of The Fixed-Point Sparse Coding Performance

Cybernetics and Information Technologies, 2014
The Sparse Coding (SC) model has been proved to be among the best neural networks which are mainly used in unsupervised feature learning for many applications.
Jiang Jingfei, Hu Rongdong, Zhang Fei, Dou Yong   +3 more
doaj   +1 more source

Interplay between circadian and other transcription factors—Implications for cycling transcriptome reprogramming

FEBS Letters, EarlyView.
This perspective highlights emerging insights into how the circadian transcription factor CLOCK:BMAL1 regulates chromatin architecture, cooperates with other transcription factors, and coordinates enhancer dynamics. We propose an updated framework for how circadian transcription factors operate within dynamic and multifactorial chromatin landscapes ...
Xinyu Y. Nie, Jerome S. Menet
wiley   +1 more source