Results 81 to 90 of about 640,180 (318)
Instance-Specific Algorithm Selection via Multi-Output Learning
Tsinghua Science and Technology, 2017 Instance-specific algorithm selection technologies have been successfully used in many research fields, such as constraint satisfaction and planning. Researchers have been increasingly trying to model the potential relations between different candidate ...
Kai Chen, Yong Dou, Qi Lv, Zhengfa Liang
doaj +1 more source
FEBS Letters, EarlyView.We identified a systemic, progressive loss of protein S‐glutathionylation—detected by nonreducing western blotting—alongside dysregulation of glutathione‐cycle enzymes in both neuronal and peripheral tissues of Taiwanese SMA mice. These alterations were partially rescued by SMN antisense oligonucleotide therapy, revealing persistent redox imbalance as ...
Sofia Vrettou, Brunhilde Wirth
wiley +1 more source
Transductive Nonnegative Matrix Tri-Factorization
IEEE Access, 2020 Nonnegative matrix factorization (NMF) decomposes a nonnegative matrix into the product of two lower-rank nonnegative matrices. Since NMF learns parts-based representation, it has been widely used as a feature learning component in many fields.
Xiao Teng +4 more
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FEBS Letters, EarlyView.In this study, we found that human cervical‐derived adipocytes maintain intracellular iron level by regulating the expression of iron transport‐related proteins during adrenergic stimulation. Melanotransferrin is predicted to interact with transferrin receptor 1 based on in silico analysis.
Rahaf Alrifai +9 more
wiley +1 more source
Resource analyses for parallel and distributed coordination [PDF]
, 2013 <p>Predicting the resources that are consumed by a program component is crucial for many parallel or distributed systems. In this context, the main resources of interest are execution time, space and communication/synchronisation costs.
Michaelson, G.J. +15 more
core +1 more source
Enhancing Stock Price Trend Prediction via a Time-Sensitive Data Augmentation Method
Complexity, 2020 Stock trend prediction refers to predicting future price trend of stocks for seeking profit maximum of stock investment. Although it has aroused broad attention in stock markets, it is still a tough task not only because the stock markets are complex and
Xiao Teng +4 more
doaj +1 more source
Structural insights into an engineered feruloyl esterase with improved MHET degrading properties
FEBS Letters, EarlyView.A feruloyl esterase was engineered to mimic key features of MHETase, enhancing the degradation of PET oligomers. Structural and computational analysis reveal how a point mutation stabilizes the active site and reshapes the binding cleft, expading substrate scope.
Panagiota Karampa +5 more
wiley +1 more source
FEBS Letters, EarlyView.Biomolecular condensates formed by fused in sarcoma (FUS) are dissolved by high ATP concentrations yet persist in cells. Using a reconstituted system, we demonstrate that valosin‐containing protein (VCP), an AAA+ ATPase, counteracts ATP‐driven dissolution of FUS condensates through its D2 ATPase activity.
Hitomi Kimura +2 more
wiley +1 more source
Malware Collusion Attack against SVM: Issues and Countermeasures
Applied Sciences, 2018 Android has become the most popular mobile platform, and a hot target for malware developers. At the same time, researchers have come up with numerous ways to deal with malware.
Hongyi Chen +3 more
doaj +1 more source
Hyperosmotic stress induces PARP1‐mediated HPF1‐dependent mono(ADP‐ribosyl)ation
FEBS Letters, EarlyView.Sorbitol‐induced hyperosmotic stress rapidly induces reversible mono(ADP‐ribosyl)ation (MARylation) on PARP1 without the signs of genotoxic signaling. We show that PARP1 autoMARylation is HPF1 dependent and forms hydroxylamine‐resistant O‐glycosidic linkages.
Anna Georgina Kopasz +11 more
wiley +1 more source