Results 41 to 50 of about 454,135 (314)
FEBS Letters, EarlyView.This perspective highlights emerging insights into how the circadian transcription factor CLOCK:BMAL1 regulates chromatin architecture, cooperates with other transcription factors, and coordinates enhancer dynamics. We propose an updated framework for how circadian transcription factors operate within dynamic and multifactorial chromatin landscapes ...
Xinyu Y. Nie, Jerome S. Menet
wiley +1 more source
Parallelizing Parallel Programs [PDF]
Proceedings of the ACM International Conference on Parallel Architectures and Compilation Techniques, 2020 Roberto Castañeda Lozano +2 more
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Disordered but rhythmic—the role of intrinsic protein disorder in eukaryotic circadian timing
FEBS Letters, EarlyView.Unstructured domains known as intrinsically disordered regions (IDRs) are present in nearly every part of the eukaryotic core circadian oscillator. IDRs enable many diverse inter‐ and intramolecular interactions that support clock function. IDR conformations are highly tunable by post‐translational modifications and environmental conditions, which ...
Emery T. Usher, Jacqueline F. Pelham
wiley +1 more source
ENTOTIC SOUND: DIAGNOSTIC PARALLELS
Инновационная медицина Кубани, 2019 We observed issues of etiology and pathogenesis, differentiatied diagnosis of entotic sound which is one of the frequent otoneurological complaints. Classification of this symptom is described.
E. V. Kolpakova +4 more
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Michael V Kalaphates — Romanos IV Diogenes: Textual parallels in the chronographia of Michael Psellos [PDF]
Zbornik Radova Vizantološkog Instituta, 2011 The books five and seven of the Chronographia contain some striking parallels between the two deposed and blinded emperors of the eleventh century, Kalaphates and Diogenes.
Vratimos Antonios
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Optimal Adjacent Output Phase Difference Assignments in One-Dimensional Parallel Switching Matrices With Four Beams [PDF]
, 2023 S. Wu +3 more
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Protein pyrophosphorylation by inositol pyrophosphates — detection, function, and regulation
FEBS Letters, EarlyView.Protein pyrophosphorylation is an unusual signaling mechanism that was discovered two decades ago. It can be driven by inositol pyrophosphate messengers and influences various cellular processes. Herein, we summarize the research progress and challenges of this field, covering pathways found to be regulated by this posttranslational modification as ...
Sarah Lampe +3 more
wiley +1 more source
Source Code for Biology and Medicine, 2011 Abstract Background With the advent of high throughput genomics and high-resolution imaging techniques, there is a growing necessity in biology and medicine for parallel computing, and with the low cost of computing, it is now cost-effective for even small labs or individuals to build their own personal computation ...
Kompass, Kenneth S +2 more
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FEBS Letters, EarlyView.Multidrug transporters BpeB and BpeF from the Gram‐negative pathogen Burkholderia pseudomallei have a hydrophilic patch in their substrate‐binding pocket. Drug susceptibility tests and growth curve analyses using an Escherichia coli recombinant expression system revealed that the hydrophilic patches of BpeB and BpeF are involved in the substrate ...
Ui Okada, Satoshi Murakami
wiley +1 more source
Mechanisms of parasite‐mediated disruption of brain vessels
FEBS Letters, EarlyView.Parasites can affect the blood vessels of the brain, often causing serious neurological problems. This review explains how different parasites interact with and disrupt these vessels, what this means for brain health, and why these processes matter. Understanding these mechanisms may help us develop better ways to prevent or treat brain infections in ...
Leonor Loira +3 more
wiley +1 more source