Results 21 to 30 of about 785 (222)
Neurovascular Contacts in the Pathophysiology of Neuralgic Amyotrophy: An Observational Study
ABSTRACT Objective Neuralgic amyotrophy (NA) is a prevalent, monophasic, multifocal immune‐mediated neuropathy. A distinctive characteristic of the disease is the occurrence of nerve or fascicle constrictions and torsions (NA‐associated focal nerve lesions, NAFL). The pathophysiology underlying this phenomenon remains to be fully elucidated.
Johannes Fabian Holle +4 more
wiley +1 more source
Recovery from acidosis is a robust trigger for loss of force in murine hypokalemic periodic paralysis. [PDF]
Periodic paralysis is an ion channelopathy of skeletal muscle in which recurrent episodes of weakness or paralysis are caused by sustained depolarization of the resting potential and thus reduction of fiber excitability.
Cannon, Stephen C +4 more
core +1 more source
Hypokalemic periodic paralysis; two different genes responsible for similar clinical manifestations [PDF]
Primary hypokalemic periodic paralysis (HOKPP) is an autosomal dominant disorder manifesting as recurrent periodic flaccid paralysis and concomitant hypokalemia. HOKPP is divided into type 1 and type 2 based on the causative gene.
Bendahhou +19 more
core +2 more sources
Adhesions’ high occurrence rates and high morbidity render them a critical challenge to be addressed. Current prevention methods, such as physical barriers, have many limitations, resulting in inconsistent safety and efficacy. This study demonstrates the potential for sprayable polymeric materials as an adhesion barrier.
Robert J. Morris III +7 more
wiley +1 more source
Skeletal muscle channelopathies: a guide to diagnosis and management [PDF]
Skeletal muscle channelopathies are a group of rare episodic genetic disorders comprising the periodic paralyses and the non-dystrophic myotonias.
Fialho, D, Holmes, S, Matthews, E
core
This review provides an overview of triboelectric nanogenerator (TENG)–based biomedical applications by classifying studies into electronic and ionic systems across attachable and implantable platforms. It summarizes key material choices, device structures, and working mechanisms that characterize current TENG‐based research, and outlines six future ...
Kyongtae Choi +12 more
wiley +1 more source
Muscle channelopathies and electrophysiological approach
Myotonic syndromes and periodic paralyses are rare disorders of skeletal muscle characterized mainly by muscle stiffness or episodic attacks of weakness.
Cherian Ajith +2 more
doaj
A transparent, deformable stevia–PVA hydrogel triboelectric nanogenerator delivers significantly enhanced mechanical strength and electrical output through biomimetic hydrogen‐bonded networks. Coupled with machine learning–assisted signal recognition, the self‐powered hydrogel enables accurate human‐motion sensing for intelligent wearable and IoT ...
Thien Trung Luu +5 more
wiley +1 more source
Genetic diagnosis and treatment progress of primary periodic paralysis
Primary periodic paralysis is autosomal dominant genetic skeletal muscle ion channelopathy. It is characterized by episodes of muscle weakness associated with lower, normal or elevated serum potassium.
Qing KE
doaj
Phosphorylation and protonation of neighboring MiRP2 sites: function and pathophysiology of MiRP2-Kv3.4 potassium channels in periodic paralysis. [PDF]
MinK-related peptide 2 (MiRP2) and Kv3.4 subunits assemble in skeletal muscle to create subthreshold, voltage-gated potassium channels. MiRP2 acts on Kv3.4 to shift the voltage dependence of activation, speed recovery from inactivation, suppress ...
Abbott, Geoffrey W +2 more
core +1 more source

