Results 1 to 10 of about 452,320 (290)

Occupational shoulder disability: functional recovery after decompression and neurolysis of the upper brachial plexus and the long thoracic nerve

International Journal of Occupational Medicine and Environmental Health, 2021
Objectives This study aimed to assess the surgical outcomes of patients with work-related upper extremity musculoskeletal disorders (UE-MSDs) who failed conservative treatment.
Rahul K. Nath, Alyssa M. Leal, Chandra Somasundaram   +2 more
doaj   +1 more source

Deep brain stimulation of the Cuneiform nucleus for levodopa-resistant freezing of gait in Parkinson’s disease: study protocol for a prospective, pilot trial

Pilot and Feasibility Studies, 2021
Background Freezing of gait (FOG) is a particularly debilitating motor deficit seen in a subset of Parkinson’s disease (PD) patients that is poorly responsive to standard levodopa therapy or deep brain stimulation (DBS) of established PD targets such as ...
Stephano J. Chang, Iahn Cajigas, James D. Guest, Brian R. Noga, Eva Widerström-Noga, Ihtsham Haq, Letitia Fisher, Corneliu C. Luca, Jonathan R. Jagid   +8 more
doaj   +1 more source

Long-term Improvements of Neuroplasty and Scalene Muscle Resection in LTN-injured Winged Scapula Patients

Plastic and Reconstructive Surgery, Global Open, 2021
Background:. Injuries to the long thoracic nerve, which directly branches off of the C6, C7, and C8 brachial plexus nerve roots, can cause scapular winging and affect shoulder movements. Long thoracic nerve injuries resulting from accidents, violence, or
Rahul K. Nath, MD, Chandra Somasundaram, PhD   +1 more
doaj   +1 more source

Clinical and functional outcome of modified Quad surgery in adult obstetric brachial plexus injury patients: Case reports

Clinics and Practice, 2019
Untreated adult obstetric brachial plexus injury (OBPI) patients, in general, use compensatory strategies to achieve their lost upper extremity functions; they cause some adverse effects. Our present study is a case series of 3 female adult OBPI patients,
Rahul K. Nath, Divya Goel, Chandra Somasundaram   +2 more
doaj   +1 more source

Acrolein scavenger dimercaprol offers neuroprotection in an animal model of Parkinson’s disease: implication of acrolein and TRPA1

Translational Neurodegeneration, 2021
Background The mechanisms underlying lesions of dopaminergic (DA) neurons, an essential pathology of Parkinson’s disease (PD), are largely unknown, although oxidative stress is recognized as a key factor.
Liangqin Shi, Yazhou Lin, Yucheng Jiao, Seth A. Herr, Jonathan Tang, Edmond Rogers, Zhengli Chen, Riyi Shi   +7 more
doaj   +1 more source

Comparative Profiling of TG2 and Its Effectors in Human Relapsing Remitting and Progressive Multiple Sclerosis

Biomedicines, 2022
Multiple Sclerosis (MS) is a chronic CNS autoimmune disease characterized by immune-mediated demyelination, axon loss, and disability. Dysregulation of transglutaminase-2 (TG2) has been implicated in disease initiation and progression.
Damien D. Pearse, Andrew B. Hefley, Alejo A. Morales, Mousumi Ghosh   +3 more
doaj   +1 more source

TNFR2 Signaling Regulates the Immunomodulatory Function of Oligodendrocyte Precursor Cells

Cells, 2021
Multiple sclerosis (MS) is a neuroimmune disorder characterized by inflammation, CNS demyelination, and progressive neurodegeneration. Chronic MS patients exhibit impaired remyelination capacity, partly due to the changes that oligodendrocyte precursor ...
Haritha L. Desu, Placido Illiano, James S. Choi, Maureen C. Ascona, Han Gao, Jae K. Lee, Roberta Brambilla   +6 more
doaj   +1 more source

Acute Putrescine Supplementation with Schwann Cell Implantation Improves Sensory and Serotonergic Axon Growth and Functional Recovery in Spinal Cord Injured Rats

Neural Plasticity, 2015
Schwann cell (SC) transplantation exhibits significant potential for spinal cord injury (SCI) repair and its use as a therapeutic modality has now progressed to clinical trials for subacute and chronic human SCI.
J. Bryan Iorgulescu, Samik P. Patel, Jack Louro, Christian M. Andrade, Andre R. Sanchez, Damien D. Pearse   +5 more
doaj   +1 more source

10-year Follow-up of Mod Quad and Triangle Tilt Surgeries in Obstetric Brachial Plexus Injury

Plastic and Reconstructive Surgery, Global Open, 2019
Aim:. To evaluate whether obstetric brachial plexus injury (OBPI) children who had mod Quad and triangle tilt surgeries maintained their recovered upper extremity functional movements over 10 years. Background:. The short-term outcomes of surgery in OBPI
Rahul K. Nath, MD, Chandra Somasundaram, PhD   +1 more
doaj   +1 more source

Recurring paralysis

BMJ Case Reports, 2009
A 22-year-old Chinese man presented with sudden onset of generalised muscular weakness and paralysis upon awakening in the morning, due to sporadic periodic paralysis (SPP), a type of hypokalaemic periodic paralysis (HPP) without hyperthyroidism or familial history of paralysis. Laboratory studies showed marked hypokalaemia (K+1.6 mmol/litre).
Hung-Wei, Lin, Tom, Chau, Chin-Sheng, Lin, Shih-Hua, Lin   +3 more
openaire   +3 more sources