Results 191 to 200 of about 327,938 (346)

Mapping Glial Autophagy Dynamics in an Amyotrophic Lateral Sclerosis Mouse Model Reveals Microglia and Astrocyte Autophagy Dysfunction

open access: yesGlia, EarlyView.
In SOD1 mice: Symptomatic spinal microglia and astrocytes show increased autophagy flux with greater dysfunction and SOD1 inclusions in astrocytes. Dysfunction was transient (end stage glia displayed control comparable levels of autophagy parameters). ABSTRACT Amyotrophic lateral sclerosis (ALS) is defined by motor neuron death.
Nirma D. Perera   +4 more
wiley   +1 more source

Conversion Surgery After Administration of a TRK Inhibitor for Unresectable Parotid Gland Secretory Carcinoma

open access: yesHead &Neck, EarlyView.
ABSTRACT Background The NTRK fusion gene is detected in most salivary gland secretory carcinomas. While tropomyosin receptor kinase (TRK) inhibitors are used for various solid tumors with the fusion gene, there are no reports regarding TRK inhibitor use for unresectable parotid gland carcinomas that subsequently shrink and become resectable.
Arisa Nagano   +11 more
wiley   +1 more source

INFANTILE PARALYSIS. [PDF]

open access: green, 1908
Robert W. Lovett
openalex   +1 more source

Median effective dosage of midazolam oral solution for preschool children in preoperative sedation

open access: yesIbrain, EarlyView.
This study aimed to detect median effective dosage (ED50) of midazolam oral solution (MOS) for preschool children in preoperative sedation. Thirty children who were scheduled for elective of the hidden penis correction surgery under general anesthesia in the pediatric surgery department were selected.
Rui Jiang   +5 more
wiley   +1 more source

Analysis of the Clinical Value of Monocyte Human Leukocyte Antigen‐DR, Procalcitonin, and C‐Reactive Protein in Sepsis

open access: yesiLABMED, EarlyView.
This study compared the clinical value of monocytic human leukocyte antigen‐DR (mHLA‐DR), procalcitonin (PCT), and C‐reactive protein (CRP) in diagnosing and predicting sepsis outcomes, providing better guidance for clinical management. The diagnostic efficacy of PCT and CRP for sepsis was superior to that of mHLA‐DR, but mHLA‐DR demonstrated a ...
Jingxiao Dong   +4 more
wiley   +1 more source

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