Results 131 to 140 of about 2,795,142 (309)

Rethinking disaster risk management and climate change adaptation [PDF]

, 2013
Australian governments face the twin challenges of dealing with extreme weather-related disasters (such as floods and bushfires) and adapting to the impacts of climate change.
Deanna Grant-Smith, Michael Howes, Kim Reis   +2 more
core  

RoundMi: A quantitative method to analyze mitochondrial morphology in mitotic cells

FEBS Open Bio, EarlyView.
RoundMi is a workflow for rapid analysis of mitochondrial morphology in mitotic cells. By combining adaptive preprocessing with automated segmentation and quantification, it enables accurate measurements from single focal plane images, reducing acquisition time and computational demands while remaining compatible with high‐throughput fixed and live ...
Elmira Parvindokht Bararpour, Christine Volmert, Valentina Piano   +2 more
wiley   +1 more source

Time‐restricted feeding prior to Mycobacterium tuberculosis infection reduces tissue CD4+ T cells with limited impact on bacterial clearance

FEBS Open Bio, EarlyView.
Time‐restricted feeding (TRF) in mice increased liver fatty acid oxidation and decreased fatty acid biosynthesis. These alterations persisted when TRF was discontinued and the host was infected with Mycobacterium tuberculosis. Pre‐exposure to TRF did not alter tissue (lung and spleen) mycobacterial burden but significantly reduced CD3+ T cells in lungs
Ashish Gupta, Nidhi Yadav, Subhasmita Das, R. Rajendra Kumar Reddy, Nupur Sharma, Amol Ratnakar Suryawanshi, Jaswinder Singh Maras, Ranjan Kumar Nanda   +7 more
wiley   +1 more source

Adaptation and Development: Whose Goals and Priorities Count?

, 2010
It has been argued that adaptation to climate change should be integrated with development activities, and that it is time to pursue its 'mainstreaming' within such programmes (Burton 2009).
Nalau, Johanna, Heyd, T.
core  

Directed evolution of enzymes at the crossroads of tradition and innovation

FEBS Open Bio, EarlyView.
An iterative cycle of data‐driven enzyme optimization comprising four stages: genetic diversification of a template enzyme, expression of protein variants, high‐throughput evaluation, and machine‐learning‐guided redesign of the next variant library.
Maria Tomkova, Andrej Mirossay, Erik Sedlak   +2 more
wiley   +1 more source

Adaptation research alliance : concept note

, 2021
The Adaptation Research Alliance (ARA) is an integral component of the Adaptation & Resilience (A&R) campaign, one of the priority areas for the COP26.
Adaptation Research Alliance
core  

Molecular characterization of covRS mutations in M1UK Streptococcus pyogenes

FEBS Open Bio, EarlyView.
Group A Streptococcus (GAS) acquires covRS mutations driving a hypervirulent bacterial state, frequently associated with invasive disease‐like necrotizing fasciitis. We demonstrate that the newly emerged M1UK GAS lineage can also acquire these mutations.
Jarrad Pritchard, Emma‐Jayne Proctor, Jiawa Wang, Nikolas P. Johnston, Andrew Hayes, Georgia McCorkell, Haibo Yu, Jai Tree, Mark R. Davies, Mark J. Walker, Ronald Sluyter, Stephan Brouwer, Martina L. Sanderson‐Smith   +12 more
wiley   +1 more source

A hybrid framework for unsupervised domain adaptation: Integrating feature alignment, parameter adaptation, and instance selection

Journal of King Saud University: Computer and Information Sciences
Unsupervised Domain Adaptation (UDA), a key subfield of Transfer Learning (TL), addresses the performance degradation caused by domain shift that occurs when a model trained on a labeled source domain is applied to an unlabeled target domain.
Shaofei Zang, Huimin Li, Guosen Xie, Xinghai Li, Nannan Lu, Jiwei Gao, Jianwei Ma   +6 more
doaj   +1 more source

Transcripts enriched in codons that trigger P‐site tRNA‐mediated mRNA decay possess stable mRNA

FEBS Open Bio, EarlyView.
PTMD codons were first described by Mendel et al. as mediators of an mRNA decay pathway dependent on the human protein CNOT3, homologous to yeast Not5. Our findings confirm that PTMD codons destabilize transcripts; however, unlike in yeast, the human pathway specifically targets and slightly destabilizes primarily stable mRNAs.
Rodolfo Lopes Carneiro, Fernando Lucas Palhano   +1 more
wiley   +1 more source

Indigenous women's preference for climate change adaptation and aquaculture development to build capacity in the Northern Territory [PDF]

, 2013
Research was carried out on South Goulburn Island, Northern Territory, to improve understandings of local, Indigenous people’s dependency on marine resources, and of their perspectives on climate change, and aquaculture as a means towards adapting to ...
Lisa Petheram, Ann Fleming, Natasha Stacey   +2 more
core