Thrombolytic proteins profiling: High‐throughput activity, selectivity, and resistance assays
We present optimized biochemical protocols for evaluating thrombolytic proteins, enabling rapid and robust screening of enzymatic activity, inhibition resistance, and fibrin affinity, stimulation, and selectivity. The outcome translates to key clinical indicators such as biological half‐life and bleeding risk. These assays streamline the development of
Martin Toul +3 more
wiley +1 more source
Parameter identification of the PV systems based on an adapted version of human evolutionary optimizer. [PDF]
Qian J, Zhang H, Wang S.
europepmc +1 more source
Overview of molecular signatures of senescence and associated resources: pros and cons
Cells can enter a stress response state termed cellular senescence that is involved in various diseases and aging. Detecting these cells is challenging due to the lack of universal biomarkers. This review presents the current state of senescence identification, from biomarkers to molecular signatures, compares tools and approaches, and highlights ...
Orestis A. Ntintas +6 more
wiley +1 more source
FlowMat: a toolbox for modeling flow reactors using physics-based and machine learning approaches for modular simulation, parameter identification, and reactor optimization. [PDF]
Knoll S +7 more
europepmc +1 more source
Parameter identification of PV solar cells and modules using bio dynamics grasshopper optimization algorithm [PDF]
Mostafa Jabari +6 more
openalex +1 more source
Hybrid Swarm Algorithms for Parameter Identification of an Actuator Model in an Electrical Machine [PDF]
Ying Wu +4 more
openalex +1 more source
Molecular determinants of signal transduction in tropomyosin receptor kinases
Tropomyosin receptor kinases control critical neuronal functions, but how do the same receptors produce diverse cellular responses? This review explores the structural mechanisms behind Trk signaling diversity, focusing on allosteric modulation and ligand bias.
Giray Enkavi
wiley +1 more source
Parameter Identification and Transition Process Online Calibration Method of Pulsed Eddy Current Receiving Coil Based on Underdamped Dynamic Response Characteristics. [PDF]
Zeng Z +10 more
europepmc +1 more source
Day/night variations of myeloid and lymphoid cell subsets in the murine inguinal lymph node
The circadian system is involved in the temporal regulation of the immune system. Our study reveals that two innate immune populations, NKT cells and neutrophils, predominate at the beginning of the day in healthy mice, highlighting how the time of day influences immune responses.
Paula M. Wagner +6 more
wiley +1 more source

