Results 31 to 40 of about 186,641 (218)

An unexpected alternative viologen electron mediator site in tungsten‐containing formate dehydrogenase

FEBS Letters, EarlyView.
An unexpected alternative interaction site for ethyl viologen was identified in formate dehydrogenase 1 from Methylorubrum extorquens. Combined mutagenesis, kinetic analysis, and docking revealed that aromatic residues near an iron–sulfur cluster enable flavin mononucleotide‐independent electron transfer, offering a framework for engineering improved ...
Eleni G. Poloniataki, Yong Hwan Kim
wiley   +1 more source

Salmonella lipopolysaccharide‐containing supported lipid bilayers as platforms to study bacteriophage interactions

FEBS Letters, EarlyView.
We present robust protocols for the preparation of supported lipid bilayers (SLBs) incorporating either Salmonella smooth LPS or outer membrane vesicles (OMVs). We use a combination of quartz crystal microbalance with dissipation (QCM‐D) and fluorescence microscopy to both characterize the SLBs of various compositions and to probe their interactions ...
Hudson P. Pace, Alyssa Borges, Charles Arnaud, Tove Karlsson, Nina K. Bröker, Stefanie Barbirz, Marta Bally   +6 more
wiley   +1 more source

Exploring the potential of history matching for land surface model calibration [PDF]

Geoscientific Model Development
With the growing complexity of land surface models used to represent the terrestrial part of wider Earth system models, the need for sophisticated and robust parameter optimisation techniques is paramount.
N. Raoult, N. Raoult, S. Beylat, S. Beylat, J. M. Salter, F. Hourdin, V. Bastrikov, C. Ottlé, P. Peylin   +8 more
doaj   +1 more source

Three phosphatase families form a community: The phosphohydrolases that act upon inositol pyrophosphates

FEBS Letters, EarlyView.
Inositol pyrophosphates are energy‐rich signaling molecules that perform critical functions in cells. Three different families of phosphatases hydrolyze the β phosphate of the inositol pyrophosphate molecules: two have narrow specificities and one is promiscuous.
Ronda J. Rolfes
wiley   +1 more source

Research on the Scheme and System Parameter Matching of a Wastewater-Driven Diaphragm Pump Group for Slurry Transport in Deep-Sea Mining

Journal of Marine Science and Engineering
Prior research has proposed a basic configuration for a deep-sea mining system integrating slurry transport and wastewater discharge, and examined the operational characteristics of water-driven diaphragm pumps.
Qiong Hu, Junxuan Feng, Yajuan Kang, Shaojun Liu, Junqiang Huang, Kaile Wang   +5 more
doaj   +1 more source

Schemes for automatic history matching of reservoir modeling: A case of Nelson oilfield in UK

Petroleum Exploration and Development, 2012
Schemes for automatic history matching of reservoir modeling are studied for the Nelson oilfield in the Central North Sea. A complete workflow of automatic history matching involves selection of reservoir variables that require modification and parameter
Alireza KAZEMI, Karl D STEPHEN
doaj   +1 more source

Exact computation of the matching distance on 2-parameter persistence modules

Journal of Computational Geometry, 2020
The matching distance is a pseudometric on multi-parameter persistence modules, defined in terms of the weighted bottleneck distance on the restriction of the modules to affine lines.
Michael Kerber, Michael Lesnick, Steve Oudot   +2 more
doaj   +1 more source

Design and analysis strategies for robust microbiome ageing research

FEBS Letters, EarlyView.
The gut microbiome changes with age and associates with age‐related morbidity and mortality, establishing it as a potential biomarker and intervention target for ageing. Realising this potential requires methodological rigour, yet distinguishing biological signals from methodological artefacts remains challenging across cohorts. This review provides an
Mark Olenik, İsmail Güderer, Yi Wang, Tayyaba Alvi, Prasoon Pandey, Handan Melike Dönertaş   +5 more
wiley   +1 more source

A design method for timeliness optimization of the round-trip actuating mechanisms of rescue vehicle-mounted drilling rigs

Meitian dizhi yu kantan
ObjectiveIn the field of mine accident rescue, creating vertical rescue channels through surface drilling operations using a rescue vehicle-mounted drilling rig (RVMDR) proves the most effective.
Chao CAO, Bingquan MAO, Zhonghai ZHANG, Renqi CHANG, Jiyun ZHAO, Jing HAN, Di HUANG   +6 more
doaj   +1 more source

Interrogating the immune landscape of microsatellite stable RAS‐mutated colon cancer

Molecular Oncology, EarlyView.
COLOSSUS project RAS‐mutated MSS colon cancer study explored transcriptomics and immune cell density by immunohistochemistry (IHC), Immunoscore (IS), ISIC/TuLIS scores, mutation counts, and detected different prevalences but similar microenvironment composition across immune markers with clinical relevance for future immunotherapy combination ...
Rodrigo Dienstmann, Eduardo García‐Galea, Alice O'Farrell, Zak Kinsella, Maxime Meylan, Florent Petitprez, Ingrid Arijs, Tom Venken, Hari Ps, Adrian Lärkeryd, Ian Miller, Janick Selves, Nadja Meindl‐Beinker, Fiorella Ruiz‐Pace, Elena Élez, Raquel Comas‐Navarro, Frank Lincoln, Dirk Fey, Gift Nyamundanda, Aoife Nolan, Joern Lewin, Raquel Perez‐Lopez, Jonathan Briody, Kathleen Bennett, Walter Kolch, David Matallanas, Alexander Kel, Enrique Arenas, Joaquín Arribas, Bart Ghesquière, Josep Tabernero, Julie Meilleroux, Deborah McNamara, Ray McDermott, Marvin Lim, Mary O'Reilly, Brian Bird, Lisa Stack, Lucia Moloney, Patrick Morris, Keith Egan, Maciej Milewski, Lars Scheuer, Joachim Behringer, Georg Bolz, Ramon Salazar, Cristina Santos, Andrea Ruiz, Orla Casey, Verena Murphy, Matthias Ebert, Livio Trusolino, Diether Lambrechts, Anguraj Sadanandam, Catherine Sautès‐Fridman, Jochen Prehn, Paolo Nuciforo, Jacques Fieschi, Florence Monville, Darran O'Connor, Wolf Fridman, Annette Byrne   +61 more
wiley   +1 more source