Results 191 to 200 of about 680,702 (313)

IMAGE REGISTRATION WITH OPTIMAL REGULARIZATION PARAMETER SELECTION BY LEARNED AUTO ENCODER FEATURES. [PDF]

Proc IEEE Int Symp Biomed Imaging, 2021
Akossi A, Wang F, Teodoro G, Kong J.
europepmc   +1 more source

Molecular characterization of covRS mutations in M1UK Streptococcus pyogenes

FEBS Open Bio, EarlyView.
Group A Streptococcus (GAS) acquires covRS mutations driving a hypervirulent bacterial state, frequently associated with invasive disease‐like necrotizing fasciitis. We demonstrate that the newly emerged M1UK GAS lineage can also acquire these mutations.
Jarrad Pritchard, Emma‐Jayne Proctor, Jiawa Wang, Nikolas P. Johnston, Andrew Hayes, Georgia McCorkell, Haibo Yu, Jai Tree, Mark R. Davies, Mark J. Walker, Ronald Sluyter, Stephan Brouwer, Martina L. Sanderson‐Smith   +12 more
wiley   +1 more source

Correction: 'Parameter selection and optimization of a computational network model of blood flow in single-ventricle patients' (2025), by Taylor-LaPole. [PDF]

J R Soc Interface
LaPole AM, Paun M, Lior D, Weigand J, Puelz C, Olufsen MS.   +5 more
europepmc   +1 more source

An Optimal Parameter Selection Method for MOMEDA Based on EHNR and Its Spectral Entropy. [PDF]

Sensors (Basel), 2021
Li Z, Ma J, Wang X, Li X.
europepmc   +1 more source

Transcripts enriched in codons that trigger P‐site tRNA‐mediated mRNA decay possess stable mRNA

FEBS Open Bio, EarlyView.
PTMD codons were first described by Mendel et al. as mediators of an mRNA decay pathway dependent on the human protein CNOT3, homologous to yeast Not5. Our findings confirm that PTMD codons destabilize transcripts; however, unlike in yeast, the human pathway specifically targets and slightly destabilizes primarily stable mRNAs.
Rodolfo Lopes Carneiro, Fernando Lucas Palhano   +1 more
wiley   +1 more source

Tuning parameter selection for a penalized estimator of species richness. [PDF]

J Appl Stat, 2021
Paynter A, Willis AD.
europepmc   +1 more source

Hyperosmotic stress‐induced redistribution of pre‐mRNA cleavage factor I subunits is associated with shifts in alternative polyadenylation

FEBS Open Bio, EarlyView.
Hyperosmotic stress triggers the relocation of the CFIm complex from the nucleus to the cytoplasm. This shift creates a nuclear ‘stoichiometric bottleneck’, limiting CFIm availability for mRNA processing. Consequently, specific mRNAs like NUDT21 and DICER1 undergo targeted 3′UTR shortening, demonstrating how spatial protein dynamics drive rapid ...
Hitomi Soumiya, Masatake Osawa, Hidefumi Fukumitsu   +2 more
wiley   +1 more source

Research on parameter selection and optimization of C4.5 algorithm based on algorithm applicability knowledge base. [PDF]

Sci Rep
Zhang Y, Xin Y, Li Q.
europepmc   +1 more source

From energy provision to protein synthesis: Tunnelling nanotubes as mediators of intercellular metabolic cooperation in cancer

FEBS Open Bio, EarlyView.
The cytoskeleton‐mediated transport of mitochondria via tunnelling nanotubes restores respiration, increases ATP production, rescues cells from apoptosis, activates the AKT/mTOR signalling pathway, promotes cell migration and invasiveness, contributes to cancer progression and treatment resistance.
Stanislava Martínková, Jan Trnka
wiley   +1 more source

Signal-to-event encoding parameter selection for multiple event classification with spiking neural networks. [PDF]

Front Neurosci
Pabian M, Rzepka D, Pawlak M, Miśkowicz M, Sroka R.   +4 more
europepmc   +1 more source