Results 131 to 140 of about 11,534,535 (349)
Hypothesis testing with a restricted parameter space [PDF]
The paper considers tests of hypothethes in parametric models in which the parameter of interest is restricted under the alternative hypothesis. As examples of hypotheses of this type can be considered multivariate one-sided hypotheses, joint one- and two-sided hypotheses, and multivariate non-negativity hypotheses.
openaire +2 more sources
Some classes of Banach spaces depending on a parameter [PDF]
Julian Musielak, Zbigniew Semadeni
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The impact of frailty syndrome on skeletal muscle histology: preventive effects of exercise
Frailty syndrome exacerbates skeletal muscle degeneration via increased ECM deposition and myofiber loss. This study, using a murine model, demonstrates that endurance exercise attenuates these histopathological alterations, preserving muscle integrity. Findings support exercise as a viable strategy to counteract frailty‐induced musculoskeletal decline
Fujue Ji+3 more
wiley +1 more source
The contrast transfer function (CTF) is an imaging aberration that is a major resolution‐limiting factor in cryo‐electron microscopy (cryo‐EM). Precise CTF estimation is key to overcoming this limitation, but is particularly challenging in cryo‐electron tomography (cryo‐ET) data. Here, we present an approach for using geometric information to assist in
Sagar Khavnekar, William Wan
wiley +1 more source
Development of 4T1 breast cancer mouse model system for preclinical carbonic anhydrase IX studies
Carbonic anhydrase IX (CAIX) is a well‐recognised therapeutic target and prognostic biomarker in cancer. We developed and characterised a robust murine breast cancer model system that is suitable for CAIX studies in vitro and in vivo—it comprises both CAIX‐positive and CAIX‐negative controls and provides a solid platform for the comprehensive ...
Zane Kalniņa+13 more
wiley +1 more source
Fill in the blanks in the parameter space of observational astronomy. [PDF]
Qian L.
europepmc +1 more source
d‐Allulose can be produced from d‐fructose by d‐allulose 3‐epimerase. Based on sequence homology information, we successfully engineered thermostable mutants with the protein engineering method. By integrating positive mutations, we constructed an enzyme that exhibits hyperthermostability without a loss in the activity.
Kensaku Shimada+3 more
wiley +1 more source
Assessing biological network dynamics: comparing numerical simulations with analytical decomposition of parameter space. [PDF]
Hari K+5 more
europepmc +1 more source
Envelope of an $n$-parameter system of surfaces in space [PDF]
Ján Čepel, Andrej Šiposs
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Earthing effects on mitochondrial function: ATP production and ROS generation
In contrast to sham and naive controls, grounded mitochondria not only exhibit significantly enhanced energy production but also demonstrate a remarkable reduction in membrane potential and oxidative stress. This suggests a profound improvement in mitochondrial health, presenting a promising avenue for therapeutic interventions.
Cecilia Giulivi, Richard Kotz
wiley +1 more source