Results 251 to 260 of about 2,720,618 (349)

Sampling of non-Gaussian Ensemble Average Propagators for the simulation of diffusion magnetic resonance images. [PDF]

Magn Reson Med
Rodríguez-Galván JR, Villacorta-Aylagas P, Merino-Caviedes S, Simmross-Wattenberg F, Castillo-Passi C, Irarrazaval P, Tristán-Vega A, Alberola-López C.   +7 more
europepmc   +1 more source

Using expert elicitation to predict feral cat, Felis catus, responses to management

Pest Management Science, EarlyView.
We generated estimates of lethal feral cat management success for 864 scenarios, only 71 lethal management scenarios met a population reduction target of 57%. Cat‐targeted poison baits, in dry conditions and arid areas were most successful. Feral cat management requires continued adaptive strategies to reduce cat impacts.
Annalie Dorph, Sarah Legge, Trent D Penman, Rebecca Cherubin, Shona Elliot‐Kerr, Erica Marshall, Kate Parkins, Guy‐Anthony Ballard   +7 more
wiley   +1 more source

Approximating the ideal observer for joint signal detection and estimation tasks by the use of Markov-Chain Monte Carlo with generative adversarial networks. [PDF]

J Med Imaging (Bellingham)
Li D, Li K, Zhou W, Anastasio MA.
europepmc   +1 more source

Intranasal diamorphine population pharmacokinetics modeling and simulation in pediatric breakthrough pain

CPT: Pharmacometrics &Systems Pharmacology, Volume 14, Issue 3, Page 435-447, March 2025.
Abstract Intranasal diamorphine (IND), approved for managing breakthrough pain in the UK, has been identified as an acceptable alternative offering effective, expedient, and less traumatic analgesia for children. However, the current dose regimen in pediatric populations relies on clinical expertise while the pharmacokinetics properties are poorly ...
Lianjin Cai, Jingchen Zhai, Beihong Ji, Fengyang Han, Taoyu Niu, Luxuan Wang, Junmei Wang   +6 more
wiley   +1 more source

Entanglement-assisted variational algorithm for discrete optimization problems. [PDF]

Commun Phys
Fioroni L, Savona V.
europepmc   +1 more source

A minimal physiologically‐based pharmacokinetic modeling platform to predict intratumor exposure and receptor occupancy of an anti‐LAG‐3 monoclonal antibody

CPT: Pharmacometrics &Systems Pharmacology, Volume 14, Issue 3, Page 460-473, March 2025.
Abstract In oncology drug development, measuring drug concentrations at the tumor site and at the targeted receptor remains an ongoing challenge. Positron emission tomography (PET)‐imaging is a promising noninvasive method to quantify intratumor exposure of a radiolabeled drug (biodistribution data) and target saturation by treatment doses in vivo ...
Robin Michelet, Klas Petersson, Marc C. Huisman, C. Willemien Menke‐van der Houven van Oordt, Iris H. C. Miedema, Andrea Thiele, Ghazal Montaseri, Alejandro Pérez‐Pitarch, David Busse   +8 more
wiley   +1 more source

A sample size analysis of a mathematical model of longitudinal tumor volume and progression‐free survival for Bayesian individual dynamic predictions in recurrent high‐grade glioma

CPT: Pharmacometrics &Systems Pharmacology, Volume 14, Issue 3, Page 495-509, March 2025.
Abstract Patients with recurrent high‐grade glioma (rHGG) have a poor prognosis with median progression‐free survival (PFS) of <7 months. Responses to treatment are heterogenous, suggesting a clinical need for prognostic models. Bayesian data analysis can exploit individual patient follow‐up imaging studies to adaptively predict the risk of progression.
Daniel J. Glazar, Solmaz Sahebjam, Hsiang‐Husan M. Yu, Dung‐Tsa Chen, Menal Bhandari, Heiko Enderling   +5 more
wiley   +1 more source

Increasing temperatures counteract the evolutionary consequences of fishing in model of Northeast Arctic Cod (Gadus morhua). [PDF]

Sci Rep
Jessen HH, Opdal AF, Enberg K.
europepmc   +1 more source

Disease–Drug–Drug Interaction of Imatinib in COVID‐19 ARDS: A Pooled Population Pharmacokinetic Analysis

CPT: Pharmacometrics &Systems Pharmacology, Volume 14, Issue 3, Page 583-595, March 2025.
ABSTRACT Prior pharmacokinetic (PK) analysis revealed that increased alpha‐1‐acid glycoprotein (AAG) levels are associated with decreased imatinib unbound fraction in coronavirus disease 2019 (COVID‐19) patients. This study aimed to investigate the PK of total and unbound concentrations of imatinib and the metabolite N‐desmethyl imatinib in ...
Medhat M. Said, Job R. Schippers, Leila Atmowihardjo, Yingxue Li, Mick S. van der Plas, Harm J. Bogaard, Lieuwe D. J. Bos, Ron A. A. Mathôt, Jurjan Aman, Eleonora L. Swart, Imke H. Bartelink   +10 more
wiley   +1 more source

Functional near-infrared spectroscopy for the detection of fear using parameterized quantum circuits. [PDF]

Sci Rep
Gómez-Sirvent JL, Fernández-Caballero A, Novais P.   +2 more
europepmc   +1 more source