Results 121 to 130 of about 128,668 (237)

Parameterized Complexity of Caching in Networks

open access: yesProceedings of the AAAI Conference on Artificial Intelligence
The fundamental caching problem in networks asks to find an allocation of contents to a network of caches with the aim of maximizing the cache hit rate. Despite the problem's importance to a variety of research areas - including not only content delivery, but also edge intelligence and inference - and the extensive body of work on empirical aspects of ...
Ganian, Robert   +2 more
openaire   +2 more sources

Serine/Threonine Kinase 33 as a Novel Target of Bufalin in Treatment of Triple‐Negative Breast Cancer

open access: yesAdvanced Science, EarlyView.
This study identified that STK33 may serve as a target of Bufalin, which induces the degradation of STK33 and inhibits the growth of TNBC. Furthermore, STK33 is highly expressed in TNBC and enhances TNBC cell proliferation by phosphorylating and stabilizing CCAR1.
Shilong Jiang   +11 more
wiley   +1 more source

RNA inverse folding can be solved in linear time for structures without isolated stacks or base pairs

open access: yesAlgorithms for Molecular Biology
Inverse folding is a classic instance of negative RNA design which consists in finding a sequence that uniquely folds into a target secondary structure with respect to energy minimization. A breakthrough result of Bonnet et al. shows that, even in simple
Théo Boury   +3 more
doaj   +1 more source

Development of a 3D Human Colon Model Along with Bioelectronics for the Induction and Monitoring of Diseases

open access: yesAdvanced Science, EarlyView.
We present a functional three‐dimensional in‐vivo‐mimicking human colon (3D‐IVM‐HC) model engineered via Freeform Reversible Embedding of Suspended Hydrogels bioprinting with gelatin methacrylate (GelMA)/alginate hydrogels. This 3D non‐animal model replicates crypt‐like architectures, epithelial polarization, and stromal–tumor interactions, showing ...
Jorge Alfonso Tavares‐Negrete   +7 more
wiley   +1 more source

Continuous Physics‐Informed Learning Expedited Battery Mechanism Decoupling

open access: yesAdvanced Science, EarlyView.
A battery modeling framework combining dual neural networks with physical prior is presented to track internal mechanisms, decouple overpotential components, and early predict aging trajectories using only DC data, eliminating the need for additional measurements.
Shanling Ji   +7 more
wiley   +1 more source

Here comes the SU(N): multivariate quantum gates and gradients [PDF]

open access: yesQuantum
Variational quantum algorithms use non-convex optimization methods to find the optimal parameters for a parametrized quantum circuit in order to solve a computational problem.
Roeland Wiersema   +4 more
doaj   +1 more source

Inverse Co‐Design of Mechanical And Sensory Properties in Soft Lattice Foams for Multifunctional Wearables

open access: yesAdvanced Science, EarlyView.
An inverse co‐design framework integrates neural networks and physics‐based models to engineer soft lattice foams with independently tunable mechanical and sensory properties. By layering architected foams and optimizing electrode placement, this method enables multifunctional wearable sensors.
Qinghua Guan   +3 more
wiley   +1 more source

Operando TEM Study of Partial Oxidation of Methane Over Pd Nanoparticles

open access: yesAdvanced Science, EarlyView.
This operando TEM study reveals that Pd nanoparticles (NPs) catalyze the partial oxidation of methane (POM) by transforming into smaller, highly dynamic mixed‐phase Pd–PdO NPs, with active sites located at the interface between the two phases. Here, metallic Pd facilitates CH4 dehydrogenation, while PdO promotes C oxidation.
Yingying Jiang   +4 more
wiley   +1 more source

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