Results 141 to 150 of about 128,668 (237)
Active Learning‐Assisted Exploration of [PO40Mo12]3− for Alzheimer's Therapy Insights
Advanced Science, EarlyView.Bayesian Optimization coupled with active learning to uncover the interaction mechanism of [PO40Mo12]3− on amyloid‐β peptide. Abstract Alzheimer's disease (AD), involving amyloid‐β (Aβ) aggregation, has potential therapeutic modulators in polyoxometalates (POMs) like [PMo12O40]3−.
Lincan Fang +3 more
wiley +1 more source
Dynamic Synthesis of Multi‐Modal Representations for CITE‐seq Data Integration and Analysis
Advanced Science, EarlyView.The accurate integration of CITE‐seq modalities faces challenges due to complex RNA‐protein nonlinear interactions and computational inefficiencies. A lightweight framework that adaptively fuses RNA and ADT modalities, and refines them through fine‐grained learning is developed to address this issue.
Yinan Shi +5 more
wiley +1 more source
Scalable parameterized quantum circuits classifier
Scientific ReportsAs a generalized quantum machine learning model, parameterized quantum circuits (PQC) have been found to perform poorly in terms of classification accuracy and model scalability for multi-category classification tasks. To address this issue, we propose a
Xiaodong Ding +5 more
doaj +1 more source
AxiomsThis paper explores the computational challenges of clique transversal problems in d-degenerate graphs, which are commonly encountered across theoretical computer science and various network applications. We examine d-degenerate graphs to highlight their
Chuan-Min Lee
doaj +1 more source
Advanced Science, EarlyView.SETComp, a transfer learning model based on permutation‐invariance, is pre‐trained on single‐compound intervention data and fine‐tuned on complex system (e.g., natural products) data. The model achieves up to 93.86% accuracy on complex system‐cell‐gene association predictions, outperforming the baseline by up to 27.59%.
Boyang Wang +4 more
wiley +1 more source
A New Cryptographic Frontier: Key-Independent Security and Post-Quantum Hardness Assumptions
IEEE Open Journal of the Computer SocietyWith the rapid advancement of quantum computing, many classical encryption schemes are becoming increasingly vulnerable to quantum attacks, highlighting the urgent need for post-quantum cryptographic solutions that can withstand this emerging threat.
Abdelkader Laouid +2 more
doaj +1 more source
Complexity of Liveness in Parameterized Systems
, 2019 We investigate the fine-grained complexity of liveness verification for leader contributor systems. These consist of a designated leader thread and an arbitrary number of identical contributor threads communicating via a shared memory. The liveness verification problem asks whether there is an infinite computation of the system in which the leader ...
Chini, Peter +2 more
openaire +5 more sources
Advanced Science, EarlyView.The paper proposes that the root cause of aging is the loss of anatomical goal‐directedness after development. Using evolutionary neural cellular automata simulations, the authors show that after the organism has reached its developmental homeostatic setpoint (the adult morphology), the absence of target state to pursue leads to a drifting anatomical ...
Léo Pio‐Lopez +2 more
wiley +1 more source
The Parameterized Complexity of k-Flip Local Search for SAT and MAX SAT [PDF]
, 2009 Stefan Szeider
openalex +1 more source