Results 201 to 210 of about 1,615,597 (299)

Molecular Dynamics‐Guided Sterol Engineering of mRNA‐Lipid Nanoparticles Reprograms Biodistribution and Enhances Spleen‐Selective Immunity

open access: yesAdvanced Science, EarlyView.
Sterol engineering enables precise control of mRNA lipid nanoparticles by tuning membrane organization. Replacing cholesterol with bile acid‐derived sterols redirects protein expression from the liver to the spleen. Notably, CA‐20 LNP enhances antigen‐specific immune responses while exhibiting a favorable safety profile, highlighting sterols as a ...
Sanghyuk Jeon   +27 more
wiley   +1 more source

Closing the Empirical Loop: Autonomous AI Agents Conduct End‐to‐end Research With Human Participants

open access: yesAdvanced Science, EarlyView.
A multi‐agent AI system autonomously executes the complete scientific workflow, from hypothesis to manuscript, across three psychological studies involving 288 participants. The system designs experiments, collects real world data, develops analysis pipelines, and writes manuscripts with theoretical rigor comparable to experienced researchers.
Gabrielle Wehr   +6 more
wiley   +1 more source

Development and Applications of a Magnetism‐Aware General‐Purpose Atomic Cluster Expansion Potential for the Fe‐O‐H Ternary System

open access: yesAdvanced Science, EarlyView.
Hydrogen‐driven iron oxide reduction, water‐iron corrosion, and hydrogen embrittlement of metallic iron share the same Fe‐O‐H chemistry. A general‐purpose Atomic Cluster Expansion potential covers this chemistry across the full concentration range with explicit Ising‐like treatment of magnetism.
Baptiste Bienvenu   +5 more
wiley   +1 more source

Selective Catalytic Production of Urea: Unravelling the Pairwise Competition on p‐d Alloy Catalysts

open access: yesAdvanced Science, EarlyView.
Unraveling the complicated competition in urea electrosynthesis, this work investigates asymmetric p‐d alloys. We establish two stage‐specific descriptors, Anchoring Affinity and Coupling Propensity, to elegantly quantify thermodynamic bottlenecks.
Qingchao Fang   +6 more
wiley   +1 more source

Benchmarking Barren Plateau Mitigation Strategies in Quantum Neural Networks on Standard and Medical Image Datasets. [PDF]

open access: yesJ Imaging
Rahman M   +10 more
europepmc   +1 more source

NbOx Mott Memristor‐Based Oscillatory P‐trit for Ternary Potts Machine

open access: yesAdvanced Science, EarlyView.
A ternary Potts machine utilizing NbOx‐based probabilistic trits (p‐trits) is demonstrated for efficient combinatorial optimization. By leveraging the electro‐thermal switching dynamics of NbOx memristors, this architecture generates three‐state stochastic fluctuations.
Hakseung Rhee   +10 more
wiley   +1 more source

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