Results 111 to 120 of about 1,953,234 (294)

Reframing BIM: Toward Epistemic Resilience in Existing-Building Representation

Infrastructures
Conventional uses of building information modeling (BIM) in existing-building representation tend to prioritize geometric consistency and efficiency, but often at the expense of interpretive depth.
Ciera Hanson, Xiaotong Liu, Mike Christenson   +2 more
doaj   +1 more source

Sketches and parametrization

Theoretical Computer Science, 1994
zbMATH Open Web Interface contents unavailable due to conflicting licenses.
Dominique Duval, Pascale Sénéchaud
openaire   +1 more source

Colorectal cancer‐derived FGF19 is a metabolically active serum biomarker that exerts enteroendocrine effects on mouse liver

Molecular Oncology, EarlyView.
Meta‐transcriptome analysis identified FGF19 as a peptide enteroendocrine hormone associated with colorectal cancer prognosis. In vivo xenograft models showed release of FGF19 into the blood at levels that correlated with tumor volumes. Tumoral‐FGF19 altered murine liver metabolism through FGFR4, thereby reducing bile acid synthesis and increasing ...
Jordan M. Beardsley, Michael W. Rohr, Joseph A. Goode, Sai Preethi Nakkina, Jignesh G. Parikh, Deborah A. Altomare   +5 more
wiley   +1 more source

Sensitivity by Parametricity

Proceedings of the ACM on Programming Languages
The work of Fuzz has pioneered the use of functional programming languages where types allow reasoning about the sensitivity of programs. Fuzz and subsequent work (e.g., DFuzz and Duet) use advanced technical devices like linear types, modal types, and partial evaluation.
Elisabet Lobo Vesga, Alejandro Russo, Marco Gaboardi, Carlos Tomé Cortiñas   +3 more
openaire   +1 more source

Parametric corecursion

Theoretical Computer Science, 2001
zbMATH Open Web Interface contents unavailable due to conflicting licenses.
openaire   +2 more sources

Identification of serum protein biomarkers for pre‐cancerous lesions associated with pancreatic ductal adenocarcinoma

Molecular Oncology, EarlyView.
This work identified serum proteins associated with pancreatic epithelial neoplasms (PanINs) and early‐stage PDAC. Proteomics screens assessed genetically engineered mice with abundant PanINs, KPC mice (Lox‐STOP‐Lox‐KrasG12D/+ Lox‐STOP‐Lox‐Trp53R172H/+ Pdx1‐Cre) before PDAC development and also early‐stage PDAC patients (n = 31), compared to benign ...
Hannah Mearns, Jaclyn S. Long, Sergio Lilla, Kelly Hodge, Marcus J. G. W. Ladds, Colin Nixon, Paula Fernández‐Palanca, Sara Zanivan, Pilar Acedo, Stephen P. Pereira, Kevin M. Ryan   +10 more
wiley   +1 more source

Genetic attenuation of ALDH1A1 increases metastatic potential and aggressiveness in colorectal cancer

Molecular Oncology, EarlyView.
Aldehyde dehydrogenase 1A1 (ALDH1A1) is a cancer stem cell marker in several malignancies. We established a novel epithelial cell line from rectal adenocarcinoma with unique overexpression of this enzyme. Genetic attenuation of ALDH1A1 led to increased invasive capacity and metastatic potential, the inhibition of proliferation activity, and ultimately ...
Martina Poturnajova, Zuzana Kozovska, Ondrej Pos, Kristina Pavlov, Sachin Gulati, Peter Makovicky, Kristina Jakic, Monika Burikova, Eva Sedlackova, Barbora Svitkova, Silvia Tyciakova, Vojtech Bystry, Nicolas Blavet, Boris Tichy, Matej Hrnciar, Jaroslav Budis, Miroslav Tomas, Peter Dubovan, Georgina Kolnikova, Veronika Repaska, Nikoleta Mojzesova, Eva Zomborska, Daniel Pindak, Michal Mego, Tomas Szemes, Miroslava Matuskova   +25 more
wiley   +1 more source

Parametric Structure Optimization of Bogie Frame Part Based on APDL

机车电传动, 2019
Aiming at improving the efficiency of modification and optimization for bogie frame part, a local parametric optimization method was proposed to optimize the structure of the supporting rib plate with transverse stops. The maximum von_Mises stress of the
Linhai WANG, Caiying MI, Huawei FANG, Zhiming WANG   +3 more
doaj  

Application of first-order sensitivity analysis to stabilisation of unstable continuous multi-degree-of-freedom parametric periodic systems

Studia Geotechnica et Mechanica
From a practical point of view, the most important feature of a parametric periodic system is the instability phenomenon. Unlike in systems with constant coefficients, in which only points of instability exist, in parametric systems, whole areas of ...
Wójcicki Zbigniew
doaj   +1 more source

Estimator Statistics from Simulation-Free Dirichlet Block-Bootstrap Resampling

Stats
Since the initiation of two variants of the bootstrap method by Efron and Rubin in the late 1970s, a variety of advancements has emerged in the literature. The subsampling of blocks enabled the estimation of the actual variance of the sample mean.
Tillmann Rosenow
doaj   +1 more source