Results 191 to 200 of about 36,073 (256)

Revisiting Variable Stars Toward the Globular Cluster NGC 6496 With ATLAS and Gaia Photometry

open access: yesAstronomische Nachrichten, EarlyView.
ABSTRACT We revisit 13 variable stars in the field of the metal‐rich globular cluster NGC 6496, discovered by Abbas et al. (2015; Astronomical Journal 149:40) (hereafter referred to as “MA15”) via time‐series data, spanning 2 years. We improve upon the MA15 characterization of the variables using ATLAS time‐series photometry data, spanning 8 years, in ...
Madison E. Martin   +2 more
wiley   +1 more source

Optimal dosing for vascular anomalies paediatric patients with population pharmacokinetic model of sirolimus

open access: yesBritish Journal of Clinical Pharmacology, EarlyView.
Abstract Aim Sirolimus is currently used off‐label for paediatric patients with vascular anomalies. However, the optimal dosage regimen for paediatric patients remains controversial. This study aimed to determine the optimal dosing regimen of sirolimus in these patients using a population pharmacokinetic (PK) model.
Seongmee Jeong   +13 more
wiley   +1 more source

Relationship between continuous infusion meropenem PK/PD target attainment and C‐reactive protein dynamics in onco‐haematologic patients with febrile neutropenia

open access: yesBritish Journal of Clinical Pharmacology, EarlyView.
Aim Meropenem is a second‐line antimicrobial agent in the treatment of febrile neutropenia in onco‐haematological patients. A population pharmacokinetic/pharmacodynamic (PK/PD) analysis for assessing the relationship between meropenem exposure and C‐reactive protein (C‐RP) over time was conducted.
Chun Liu   +7 more
wiley   +1 more source

Development of a population pharmacokinetic model using combined paediatric and adult data for four pulmonary arterial hypertension drugs

open access: yesBritish Journal of Clinical Pharmacology, EarlyView.
Aims Pulmonary arterial hypertension (PAH) is a syndrome characterized by elevated pulmonary artery pressure. We developed a population pharmacokinetic (PPK) model using combined plasma drug concentration data from Japanese paediatric (<15 years) and adult (≥15 years) patients with PAH to investigate the pharmacokinetic characteristics of PAH ...
Motoyasu Miura   +13 more
wiley   +1 more source

An Improved Pooled Logistic Regression Implementation. [PDF]

open access: yesEpidemiology
Zivich PN   +5 more
europepmc   +1 more source

Pharmacometric evaluation of pre‐referral rectal artesunate in children with severe malaria

open access: yesBritish Journal of Clinical Pharmacology, EarlyView.
Aims Parenteral artesunate is the preferred first‐line treatment for severe malaria. Pre‐referral rectal artesunate suppositories are recommended where parenteral treatment is inaccessible. In this study, we compared dihydroartemisinin exposure and model‐predicted early parasite clearance following rectal artesunate and intravenous artesunate in ...
Ayorinde Adehin   +6 more
wiley   +1 more source

Estimation of the sample size to determine gas flux in finishing steers under confined conditions using alternative statistical approaches. [PDF]

open access: yesTransl Anim Sci
Vargas JJ   +10 more
europepmc   +1 more source

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