Results 41 to 50 of about 36,300 (256)

Simultaneous Inference of Gene Isoform Expression for RNA Sequencing Data

open access: yesRevstat Statistical Journal, 2020
In this article, we describe simultaneous inferential methods in detecting differentially expressed gene isoforms based on the Poisson generalized linear models. We derive the joint asymptotic distribution of pivotal quantities.
Bo Li
doaj   +1 more source

Molecular dynamics simulations of positively selected codons in FcγRI reveal novel biochemical binding properties

open access: yesFEBS Open Bio, EarlyView.
Evolutionary analysis across 32 placental mammals identified positive selection at residues H148 and W149 in the immune receptor FcγR1. Ancestral reconstruction combined with molecular dynamics simulations reveals how these mutations may influence receptor structure and dynamics, providing insight into the evolution of antibody recognition and immune ...
David A. Young   +7 more
wiley   +1 more source

Analysis of maximum precipitation in Thailand using non‐stationary extreme value models

open access: yesAtmospheric Science Letters, 2023
Non‐stationarity in heavy rainfall time series is often apparent in the form of trends because of long‐term climate changes. We have built non‐stationary (NS) models for annual maximum daily (AMP1) and 2‐day precipitation (AMP2) data observed between ...
Thanawan Prahadchai   +3 more
doaj   +1 more source

On Parametric Bootstrap Methods for Small Area Prediction

open access: yesJournal of the Royal Statistical Society Series B: Statistical Methodology, 2006
SummaryThe particularly wide range of applications of small area prediction, e.g. in policy making decisions, has meant that this topic has received substantial attention in recent years. The problems of estimating mean-squared predictive error, of correcting that estimator for bias and of constructing prediction intervals have been addressed by ...
Hall, Peter, Maiti, Tapabrata
openaire   +2 more sources

Molecular characterization of covRS mutations in M1UK Streptococcus pyogenes

open access: yesFEBS Open Bio, EarlyView.
Group A Streptococcus (GAS) acquires covRS mutations driving a hypervirulent bacterial state, frequently associated with invasive disease‐like necrotizing fasciitis. We demonstrate that the newly emerged M1UK GAS lineage can also acquire these mutations.
Jarrad Pritchard   +12 more
wiley   +1 more source

Hyperbolic Cosine–Exponentiated Exponential Lifetime Distribution and its Application in Reliability [PDF]

open access: yesInternational Journal of Supply and Operations Management, 2017
Recently, Kharazmi and Saadatinik (2016) introduced a new family of lifetime distributions called hyperbolic cosine – F (HCF) distribution. In the present paper, it is focused on a special case of HCF family with exponentiated exponential distribution as
Omid Kharazmi
doaj   +2 more sources

Parametric and nonparametric bootstrap methods for general MANOVA

open access: yesJournal of Multivariate Analysis, 2015
zbMATH Open Web Interface contents unavailable due to conflicting licenses.
Frank Konietschke   +3 more
openaire   +2 more sources

Avidin is evolutionarily conserved in fish but dispensable for development and resistance against Streptococcus agalactiae in zebrafish

open access: yesFEBS Open Bio, EarlyView.
The presence of biotin‐binding avidin proteins in fish and their biological significance are poorly characterized. We cataloged fish avidins and demonstrate that they are widely present and evolutionarily conserved. We created avd knockout zebrafish and show that zebavidin is dispensable for development and that resistance of avd knockout embryos in ...
Anni K. Saralahti   +5 more
wiley   +1 more source

Selected Statistical Tests for Median and Their Properties

open access: yesActa Universitatis Lodziensis. Folia Oeconomica, 2017
In the paper, a selection of statistical tests for median are presented. In particular, parametric and nonparametric significance tests are considered.
Dorota Pekasiewicz, Agata Szczukocka
doaj   +1 more source

Risk of Non‐Arteritic Anterior Ischemic Optic Neuropathy in Idiopathic Intracranial Hypertension Patients Treated with GLP‐1 Receptor Agonists

open access: yesAnnals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Introduction Glucagon‐like peptide‐1 receptor agonists (GLP‐1 RAs) have demonstrated significant weight‐reducing effects and may offer benefits in idiopathic intracranial hypertension (IIH); however, recent concerns about the risk of non‐arteritic anterior ischemic optic neuropathy (NAION) have emerged.
Faisal A. Al‐Harbi   +9 more
wiley   +1 more source

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