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Comparison of Parametric and Bootstrap Method in Bioequivalence Test [PDF]

The Korean Journal of Physiology and Pharmacology, 2009
The estimation of 90% parametric confidence intervals (CIs) of mean AUC and Cmax ratios in bioequivalence (BE) tests are based upon the assumption that formulation effects in log-transformed data are normally distributed. To compare the parametric CIs with those obtained from nonparametric methods we performed repeated estimation of bootstrap-resampled
Byung-Jin, Ahn, Dong-Seok, Yim
openaire   +2 more sources

Comparison of nonparametric estimators versus parametric for reliability function

Ingeniería Investigación y Desarrollo, 2015
One of the main objectives of the area of realiability is to estimate the function of reliability, where traditionally are used non parametric estimators, being more efficient in sample of big sizes.
Javier Ramírez-Montoya
doaj   +1 more source

Estimator Statistics from Simulation-Free Dirichlet Block-Bootstrap Resampling

Stats
Since the initiation of two variants of the bootstrap method by Efron and Rubin in the late 1970s, a variety of advancements has emerged in the literature. The subsampling of blocks enabled the estimation of the actual variance of the sample mean.
Tillmann Rosenow
doaj   +1 more source

Statistical Analysis and Theoretical Framework for a Partially Accelerated Life Test Model with Progressive First Failure Censoring Utilizing a Power Hazard Distribution

Mathematics, 2023
Monitoring life-testing trials for a product or substance often demands significant time and effort. To expedite this process, sometimes units are subjected to more severe conditions in what is known as accelerated life tests.
Amel Abd-El-Monem, Mohamed S. Eliwa, Mahmoud El-Morshedy, Afrah Al-Bossly, Rashad M. EL-Sagheer   +4 more
doaj   +1 more source

Hyperbolic Cosine–Exponentiated Exponential Lifetime Distribution and its Application in Reliability [PDF]

International Journal of Supply and Operations Management, 2017
Recently, Kharazmi and Saadatinik (2016) introduced a new family of lifetime distributions called hyperbolic cosine – F (HCF) distribution. In the present paper, it is focused on a special case of HCF family with exponentiated exponential distribution as
Omid Kharazmi
doaj   +2 more sources

Non-parametric and semi-parametric support estimation using SEquential RESampling random walks on biomolecular sequences

Algorithms for Molecular Biology, 2020
Non-parametric and semi-parametric resampling procedures are widely used to perform support estimation in computational biology and bioinformatics. Among the most widely used methods in this class is the standard bootstrap method, which consists of ...
Wei Wang, Jack Smith, Hussein A. Hejase, Kevin J. Liu   +3 more
doaj   +1 more source

Analysis of maximum precipitation in Thailand using non‐stationary extreme value models

Atmospheric Science Letters, 2023
Non‐stationarity in heavy rainfall time series is often apparent in the form of trends because of long‐term climate changes. We have built non‐stationary (NS) models for annual maximum daily (AMP1) and 2‐day precipitation (AMP2) data observed between ...
Thanawan Prahadchai, Yonggwan Shin, Piyapatr Busababodhin, Jeong‐Soo Park   +3 more
doaj   +1 more source

Molecular dynamics simulations of positively selected codons in FcγRI reveal novel biochemical binding properties

FEBS Open Bio, EarlyView.
Evolutionary analysis across 32 placental mammals identified positive selection at residues H148 and W149 in the immune receptor FcγR1. Ancestral reconstruction combined with molecular dynamics simulations reveals how these mutations may influence receptor structure and dynamics, providing insight into the evolution of antibody recognition and immune ...
David A. Young, Omar Arias‐Gaguancela, Fiona Gibson, Morgan Grainger, Jodie Score, Amit Nathubhai, Mauricio Cafiero, Lee Richard Machado   +7 more
wiley   +1 more source

On Parametric Bootstrap Methods for Small Area Prediction

Journal of the Royal Statistical Society Series B: Statistical Methodology, 2006
SummaryThe particularly wide range of applications of small area prediction, e.g. in policy making decisions, has meant that this topic has received substantial attention in recent years. The problems of estimating mean-squared predictive error, of correcting that estimator for bias and of constructing prediction intervals have been addressed by ...
Hall, Peter, Maiti, Tapabrata
openaire   +2 more sources

Testing Equality of Several Distributions at High Dimensions: A Maximum-Mean-Discrepancy-Based Approach

Mathematics, 2023
With the development of modern data collection techniques, researchers often encounter high-dimensional data across various research fields. An important problem is to determine whether several groups of these high-dimensional data originate from the ...
Zhi Peng Ong, Aixiang Andy Chen, Tianming Zhu, Jin-Ting Zhang   +3 more
doaj   +1 more source