Results 191 to 200 of about 39,366 (255)

Zebrafish xenograft models as a fast platform for metastasis diagnosis and cisplatin response of head and neck squamous cell carcinoma

Animal Models and Experimental Medicine, EarlyView.
A zebrafish xenograft model accurately distinguishes metastatic from non‐metastatic HNSCC and recapitulates cisplatin sensitivity/resistance patterns. Using patient‐derived tumors, it predicts individual therapeutic responses, offering a rapid, clinically applicable platform for guiding personalized treatment. Abstract Background Head and neck squamous
Lu Chen, Shu Sun, Yujia Liu, Liehao Jiang, Cuiyun Wu, Ting Liu, Yujiao Zhao, Yuwei Liu, Lu Liu, Qi Wang, Xiaowei Zheng, Ping Huang   +11 more
wiley   +1 more source

Extension of overlap measures for Multi-Class Biomarker Evaluation in Alzheimer's Disease. [PDF]

Sci Rep
Sierra Marquina VM, Pardo MDC, Franco-Pereira AM.   +2 more
europepmc   +1 more source

Scaling and ecomorphology of lagomorph body shape and appendicular skeleton

The Anatomical Record, EarlyView.
Abstract Body shape is one of the most prominent features of phenotypic variation. Yet, mammalian body shapes are poorly quantified and the underlying components contributing to its diversity and its relationship to other skeletal components are rarely tested.
Nia Brice, Coby Huizenga, Chris J. Law
wiley   +1 more source

Biomechanical strain patterns in Meckel's cartilage underlie mandibular variation in FGFR2 mouse models

The Anatomical Record, EarlyView.
Abstract Sequence variations in fibroblast growth factor receptor 2 (FGFR2) are associated with craniosynostosis syndromes, disrupting craniofacial development, yet early mandibular alterations remain poorly characterized. This study examined Meckel's cartilage (MC) and mandibular morphology in mouse models of Apert (Fgfr2+/P253R) and Crouzon ...
Fred R. Foster, Alexandre Freire, Ana Cláudia Rossi, Jordan Wilson, Joan T. Richtsmeier, Kazuhiko Kawasaki, Felippe B. Prado, Susan M. Motch Perrine   +7 more
wiley   +1 more source

Bridging tumor growth dynamics and survival in preclinical oncology drug development - a Tumor Growth Inhibition and Time-to-Event (TGI-TTE) modeling framework. [PDF]

Cancer Chemother Pharmacol
Niloy KK, Horn J, Bhuiyan NH, Bhosale SS, Shaaban KA, Prisinzano TE, Thorson JS, Rohr J, Leggas M.   +8 more
europepmc   +1 more source

Computed Tomography‐Based Morphometric Analysis Reveals Intercondylar Notch Stenosis and Osteophytes Are Associated With Anterior Cruciate Ligament Injury

Arthroscopy, EarlyView.
Purpose To quantitatively assess intercondylar notch morphometrics using 3‐dimensional computed tomography reconstruction, evaluate their association with anterior cruciate ligament (ACL) injury in Asian populations, and investigate the prevalence of osteophytes in patients with ACL injury.
Xiaozhong Ma, WenMing Jiang, Chao Lu, Tongyue Ji, Su Yan, Heng Zhu, Xue He, Hao Shu, Lei Wang, Luning Sun   +9 more
wiley   +1 more source

An Assessment of Reliability Estimation Methods for Binomial Health Care Quality Measures. [PDF]

Stat Med
Aume L, White W, Chen PH, Geppert J.
europepmc   +1 more source

A novel parametric predictive bootstrap method

Communications in Statistics - Theory and Methods
Abdulrahman M. A. Aldawsari, Frank P.A. Coolen, Tahani Coolen-Maturi   +2 more
openaire   +1 more source

A Metagenome‐Assembled Genome Catalog From the Global Ruminant Microbiomes

Animal Research and One Health, EarlyView.
The Ruminant Gastrointestinal MAG Catalog (RGMC) is a comprehensive global resource offering 40,812 strain‐level genomes across 53 bacterial and 4 archaeal classes. It greatly surpasses prior efforts in scale and diversity, serving as an essential foundation for research in ruminant nutrition, microbial function, and methane mitigation.
Shizhe Zhang, Qiushuang Li, Bingzi Ouyang, Wenxing Wang, Xiang Zhou, Xiumin Zhang, Rong Wang, Zhiliang Tan, Min Wang   +8 more
wiley   +1 more source

From multiplicity of infection to force of infection in sparsely sampled high-transmission <i>Plasmodium falciparum</i> populations. [PDF]

Elife
Zhan Q, Tiedje KE, Day KP, Pascual M.
europepmc   +1 more source