Results 141 to 150 of about 1,042,408 (297)
TECHNICAL CHANGE AND EFFICIENCY AT US LAND GRANT UNIVERSITIES: IS THERE ANY FAT LEFT TO CUT? [PDF]
This work uses non-parametric efficiency analysis and a unique panel data set to analyze efficiency and technical change at US universities from 1981-1998 with a special emphasis on Land Grant institutions.
Barham, Bradford L. +3 more
core +1 more source
Molecular Oncology, EarlyView.We have established a humanized orthotopic patient‐derived xenograft (Hu‐oPDX) mouse model of high‐grade serous ovarian cancer (HGSOC) that recapitulates human tumor–immune interactions. Using combined anti‐PD‐L1/anti‐CD73 immunotherapy, we demonstrate the model's improved biological relevance and enhanced translational value for preclinical ...
Luka Tandaric +10 more
wiley +1 more source
How life expectancy varies with perturbations in age-specific mortality
Demographic Research, 2012 BACKGROUND A naturally arising question in demography is how a given change in mortality affects life expectancy. Scholars have targeted this question with different aims and from differentperspectives.
Tomasz Wrycza, Annette Baudisch
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Tests for Deterministic Parametric Structural Change in Regression Models [PDF]
The problem of structural change justifiably attracts considerable attention in econometrics. A number of different paradigms have been adopted ranging from structural breaks which are sudden and rare to time-varying coefficient models which exhibit ...
George Kapetanios
core
Molecular Oncology, EarlyView.Pancreatic sensory neurons innervating healthy and PDAC tissue were retrogradely labeled and profiled by single‐cell RNA sequencing. Tumor‐associated innervation showed a dominant neurofilament‐positive subtype, altered mitochondrial gene signatures, and reduced non‐peptidergic neurons.
Elena Genova +14 more
wiley +1 more source
KDM7A and KDM1A inhibition suppresses tumour promoting pathways in prostate cancer
Molecular Oncology, EarlyView.Treatment resistance is a major challenge for patients with advanced prostate cancer. This study examined an alternative approach to target the major prostate cancer‐promoting pathway by targeting epigenetic factors, whose levels are higher in tumours.
Jennie N Jeyapalan +16 more
wiley +1 more source
Dynamic analysis of dissipative structures undergoing parametric changes [PDF]
Incertitudes et fiabilité des systèmes multiphysiques, 2021 Omar Dadah +2 more
openaire +2 more sources
Molecular Oncology, EarlyView.We analyze cisplatin–DNA adducts (CDAs) and double‐strand breaks (DSBs) in a cell‐cycle‐dependent manner. We find that CDAs form similarly across all cell cycle phases. DSBs arise only in S‐phase. CDAs might not directly impair DSB repair, but S‐phase DSB lesions evolve in the presence of CDAs and disrupt repair in G2, also causing radiosensitization ...
Ye Qiu +10 more
wiley +1 more source
Hijacking emergency granulopoiesis: Neutrophil ontogeny and reprogramming in cancer
Molecular Oncology, EarlyView.Neutrophils are highly plastic innate immune cells; their functions in cancer extend beyond the tumour microenvironment. This Review summarises current understanding of neutrophil maturation and heterogeneity and highlights tumour‐induced granulopoiesis as a systemic programme that expands immature, immunosuppressive neutrophils via tumour‐derived ...
Gabriela Marinescu, Yi Feng
wiley +1 more source
Parametric Vibrations of Nonlinearly Viscoelastic Shell Enclosed in Viscoelastic Matrix
Механика машин, механизмов и материалов, 2009 In the paper, by means of the variational principle investigate parametric vibrations of a thin, in homogeneous in thickness viscoelastic damageable cylindrical shell with viscoelastic filler, under the action of external pressure p=p0+p1sinω1t (where p0
I.T. Pirmamedov
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