Real‐World Performance of CSF Kappa Free Light Chains in the 2024 McDonald Criteria
ABSTRACT Objective Kappa free light chains (KFLCs) in the cerebrospinal fluid (CSF) have a similar performance to CSF‐restricted oligoclonal bands (OCB) for multiple sclerosis (MS) diagnosis. To help with implementation, we set out to resolve several remaining uncertainties: (1) performance in a real‐world cohort and the 2024 McDonald criteria; (2 ...
Maya M. Leibowitz +11 more
wiley +1 more source
Mesoscale Steady-State Dynamics Modeling and Parametric Analysis of the Viscoelastic Response of Asphalt-Bonded Calcareous Sand. [PDF]
Xie L, Pang B, Cao P, Wang J, Tan Z.
europepmc +1 more source
ABSTRACT Objective To investigate the value of constructing models based on habitat radiomics and pathomics for predicting the risk of progression in high‐grade gliomas. Methods This study conducted a retrospective analysis of preoperative magnetic resonance (MR) images and pathological sections from 72 patients diagnosed with high‐grade gliomas (52 ...
Yuchen Zhu +14 more
wiley +1 more source
Influence of Elliptical Fiber Cross-Section Geometry on the Transverse Tensile Response of UD-CFRP Plies Based on Parametric Micromechanical RVE Analysis. [PDF]
Wu Z, Qian J, Peng X.
europepmc +1 more source
ABSTRACT Objective Glioma recurrence severely impacts patient prognosis, with current treatments showing limited efficacy. Traditional methods struggle to analyze recurrence mechanisms due to challenges in assessing tumor heterogeneity, spatial dynamics, and gene networks.
Lei Qiu +10 more
wiley +1 more source
Inspection of stability of a general roll-damping of a ship via non-perturbative approach. [PDF]
Moatimid GM, Mohamed MAA, Abohamer MK.
europepmc +1 more source
ABSTRACT Objectives WHO grade 4 astrocytomas are associated with poor prognosis, and their prognostic factors remain controversial. This study aimed to identify the prognostic factors and develop a management algorithm for these patients. Methods This study retrospectively included 151 CNS5 adult grade 4 astrocytomas from two medical centers.
Jiawei Cai +13 more
wiley +1 more source
An innovative inspection of a cantilever beam exposed to principal parametric excitation. [PDF]
Moatimid GM, Amer TS, Mohamed MAA.
europepmc +1 more source
Clustering Algorithm Reveals Dopamine‐Motor Mismatch in Cognitively Preserved Parkinson's Disease
ABSTRACT Objective To explore the relationship between dopaminergic denervation and motor impairment in two de novo Parkinson's disease (PD) cohorts. Methods n = 249 PD patients from Parkinson's Progression Markers Initiative (PPMI) and n = 84 from an external clinical cohort.
Rachele Malito +14 more
wiley +1 more source
Digital twin-based machine learning framework for predicting nonlinear seismic response of reinforced concrete shear walls using analytical data. [PDF]
Kuria KK, Kegyes-Brassai O.
europepmc +1 more source

