Results 141 to 150 of about 1,068,788 (332)

Modular design workflow for 3D printable bioresorbable patient-specific bone scaffolds: extended features and clinical validation

Frontiers in Bioengineering and Biotechnology
A previously in-house developed patient-specific scaffold design workflow was extended with new features to overcome several limitations and to broaden its adaptability to diverse bone defects, thereby enhancing its fit for routine clinical use.
Buddhi Herath, Buddhi Herath, Buddhi Herath, Buddhi Herath, Markus Laubach, Markus Laubach, Markus Laubach, Markus Laubach, Sinduja Suresh, Sinduja Suresh, Sinduja Suresh, Sinduja Suresh, Beat Schmutz, Beat Schmutz, Beat Schmutz, Beat Schmutz, J. Paige Little, J. Paige Little, J. Paige Little, J. Paige Little, Prasad K. D. V. Yarlagadda, Prasad K. D. V. Yarlagadda, Prasad K. D. V. Yarlagadda, Heide Delbrück, Frank Hildebrand, Dietmar W. Hutmacher, Dietmar W. Hutmacher, Dietmar W. Hutmacher, Dietmar W. Hutmacher, Marie-Luise Wille, Marie-Luise Wille, Marie-Luise Wille, Marie-Luise Wille   +32 more
doaj   +1 more source

Correction: Andrade et al. The Adaptive Power of Ammophila arenaria: Biomimetic Study, Systematic Observation, Parametric Design and Experimental Tests with Bimetal. Polymers 2021, 13, 2554. [PDF]

Polymers (Basel), 2023
Andrade TAB, Beirão JNDC, Arruda AJV, Cruz C.   +3 more
europepmc   +1 more source

The Relative Efficiency of Active Labour Market Policies: Evidence from a Social Experiment and Non-Parametric Methods [PDF]

We re-analyze the effects of a Danish active labour market program social experiment that included a range of sub-treatments, including monitoring, job search assistance and training.
Rosholm, Michael, Svarer, Michael, Vikström, Johan   +2 more
core  

In vitro models of cancer‐associated fibroblast heterogeneity uncover subtype‐specific effects of CRISPR perturbations

Molecular Oncology, EarlyView.
Development of therapies targeting cancer‐associated fibroblasts (CAFs) necessitates preclinical model systems that faithfully represent CAF–tumor biology. We established an in vitro coculture system of patient‐derived pancreatic CAFs and tumor cell lines and demonstrated its recapitulation of primary CAF–tumor biology with single‐cell transcriptomics ...
Elysia Saputra, Shamsudheen Karuthedath Vellarikkal, Lixia Li, Hong Sun, Khoa Nguyen, Amber Montano, Suchitra Natarajan, Federica Piccioni, Alex Michael Tamburino, Xin Yu, Aleksandra Katarzyna Olow   +10 more
wiley   +1 more source

The Adaptive Power of Ammophila arenaria: Biomimetic Study, Systematic Observation, Parametric Design and Experimental Tests with Bimetal. [PDF]

Polymers (Basel), 2021
Andrade TAB, Beirão JNDC, Arruda AJV, Cruz C.   +3 more
europepmc   +1 more source

Molecular characterisation of human penile carcinoma and generation of paired epithelial primary cell lines

Molecular Oncology, EarlyView.
Generation of two normal and tumour (cancerous) paired human cell lines using an established tissue culture technique and their characterisation is described. Cell lines were characterised at cellular, protein, chromosome and gene expression levels and for HPV status.
Simon Broad, Mahmood Hachim, Tom Bertin, Karolina Penderecka, Rifat Hamoudi, Saif Khan, Rui Henrique, Natalie Bergmoser, Manit Arya, Kalle Sipila, Matteo Vietri Rudan, Asif Muneer, Aamir Ahmed   +12 more
wiley   +1 more source

Transcriptional network analysis of PTEN‐protein‐deficient prostate tumors reveals robust stromal reprogramming and signs of senescent paracrine communication

Molecular Oncology, EarlyView.
Combining PTEN protein assessment and transcriptomic profiling of prostate tumors, we uncovered a network enriched in senescence and extracellular matrix (ECM) programs associated with PTEN loss and conserved in a mouse model. We show that PTEN‐deficient cells trigger paracrine remodeling of the surrounding stroma and this information could help ...
Ivana Rondon‐Lorefice, Jose I. Lopez, Aitziber Ugalde‐Olano, Maite Zufiaurre, Ianire Astobiza, Natalia Martin‐Martin, Laura Bozal‐Basterra, Saioa Garcia‐Longarte, Amaia Zabala‐Letona, Sofia Rey, Aida Santos‐Martin, Miguel Unda, Ana Loizaga‐Iriarte, Mariona Graupera, Paolo Nuciforo, Arkaitz Carracedo, Isabel Mendizabal   +16 more
wiley   +1 more source

Next‐generation proteomics improves lung cancer risk prediction

Molecular Oncology, EarlyView.
This is one of very few studies that used prediagnostic blood samples from participants of two large population‐based cohorts. We identified, evaluated, and validated an innovative protein marker model that outperformed an established risk prediction model and criteria employed by low‐dose computed tomography in lung cancer screening trials.
Megha Bhardwaj, Clara Frick, Ben Schöttker, Bernd Holleczek, Hermann Brenner   +4 more
wiley   +1 more source

Parametric Modeling and Column Grid Analysis of the Sakyamuni Pagoda at Fogong Temple: Insights into the Yingxian Wooden Pagoda

Buildings
The Sakyamuni Pagoda of Fogong Temple, also known as the Yingxian Wooden Pagoda or the Wooden Pagoda of Ying County, is China’s oldest and tallest wooden pagoda.
Daoru Wang, Stephanie Yanqiu Li, Ruguan Liu, Jianxin Hu, Ang Wang   +4 more
doaj   +1 more source

Potential therapeutic targeting of BKCa channels in glioblastoma treatment

Molecular Oncology, EarlyView.
This review summarizes current insights into the role of BKCa and mitoBKCa channels in glioblastoma biology, their potential classification as oncochannels, and the emerging pharmacological strategies targeting these channels, emphasizing the translational challenges in developing BKCa‐directed therapies for glioblastoma treatment.
Kamila Maliszewska‐Olejniczak, Karolina Pytlak, Sandra Jaworowska, Bogusz Kulawiak, Piotr Bednarczyk   +4 more
wiley   +1 more source