Results 191 to 200 of about 1,068,788 (332)

A Parametric Sizing Methodology for Ground-Based Autonomous Delivery Robot for Early Design Stage

Inyoung Lee, Jeong-Hwan Kim, Hyunsoo Kim, Younghyo Kim, Jichul Kim, Kwanjung Yee   +5 more
openalex   +1 more source

Rethinking plastic waste: innovations in enzymatic breakdown of oil‐based polyesters and bioplastics

FEBS Open Bio, EarlyView.
Plastic pollution remains a critical environmental challenge, and current mechanical and chemical recycling methods are insufficient to achieve a fully circular economy. This review highlights recent breakthroughs in the enzymatic depolymerization of both oil‐derived polyesters and bioplastics, including high‐throughput protein engineering, de novo ...
Elena Rosini, Nicolò Antonelli, Gianluca Molla   +2 more
wiley   +1 more source

Integrated CAD/CAM Approach for Parametric Design and High Precision Fabrication of Planar Curvilinear Structures. [PDF]

Micromachines (Basel)
Churchill-Baird JT, Tutunea-Fatan OR, Bordatchev EV.   +2 more
europepmc   +1 more source

Indoleamine 2,3‐dioxygenase 1 inhibition reverses cancer‐associated fibroblast‐mediated immunosuppression in high‐grade serous ovarian cancer

FEBS Open Bio, EarlyView.
CAF‐mediated immunosuppression in ovarian cancer is driven by IDO1, reducing T‐cell function. Inhibiting IDO1 restores T‐cell proliferation and cytotoxicity, increases cancer cell apoptosis, and may help overcome CAF‐induced immune suppression in high‐grade serous ovarian cancer. Targeting IDO1 may improve antitumor immunity.
Hyewon Lee, Jung Yoon Ho, In Sun Hwang, Youn Jin Choi   +3 more
wiley   +1 more source

Parametric design and multiple objective intelligent optimization of marine nuclear turbine aerothermodynamics under variable conditions. [PDF]

Sci Rep
Zhang L, Chen G, Shi YA, Xie L.
europepmc   +1 more source

A Parametric Design Method for Optimal Quick Diagnostic Software. [PDF]

Sensors (Basel), 2019
Yi XJ, Hou P.
europepmc   +1 more source

Parametric Design and Geometric Optimization for Deployable Domes Based on the icosahedron frequency with hexagonal modules

Omar-Fabrisio Avellaneda-López, Marilena Christodoulou, M. Mendoza   +2 more
openalex   +2 more sources

Overexpression of CDT1 inhibits cell cycle progression at S phase by interacting with the mini‐chromosome maintenance complex and causes DNA damage

FEBS Open Bio, EarlyView.
CDT1 is an essential protein for DNA replication licensing that loads the MCM complex, the eukaryotic replicative DNA helicase, onto replication origins. Overexpression of CDT1 induces cell cycle arrest at the S phase. Here we showed CDT1 inhibits the progression of replication forks by interacting with the MCM complex, leading to the stalling and ...
Takashi Tsuyama, Nonoka Takayama, Rina Tanaka, Yuuki Arai, Yohko Yamaguchi, Yuko Nawata, Yutaro Azuma, Shusuke Tada   +7 more
wiley   +1 more source

The Parametric Design Genealogy of Zaha Hadid

, 2015
Youngjin Lee
openalex   +1 more source

A general model for analysis of linear and hyperbolic enzyme inhibition mechanisms

FEBS Open Bio, EarlyView.
We developed a general enzyme kinetic model that integrates these six basic inhibition mechanism onto a single one. From this model, we deduced a general enzyme kinetic equation that through modulation of simple parameters, γ (the relative inhibitor affinity for two binding sites) and β (the reactivity of the enzyme–substrate–inhibitor complex), is ...
Rafael S. Chagas, Sandro R. Marana
wiley   +1 more source