Results 101 to 110 of about 702,666 (251)
Molecular Oncology, EarlyView.Partial inhibition of focal adhesion kinase (FAK) can paradoxically promote tumor growth, rather than simply producing a weaker antitumor effect than that observed with strong FAK suppression. In breast cancer and melanoma models, targeting p110δ PI3K, particularly in macrophages, counteracted these tumor‐promoting effects, highlighting the importance ...
Lydia Xenou +4 more
wiley +1 more source
Fractional Mathieu Equation with Two Fractional Derivatives and Some Applications
Fractal and FractionalThe importance of this research comes from the several applications of the Mathieu equation and its generalizations in many scientific fields. Two models of fractional Mathieu equations are provided using Katugampola fractional derivatives in the sense ...
Ahmed Salem +2 more
doaj +1 more source
Molecular Oncology, EarlyView.This study integrates publicly available transcriptomic datasets to identify molecular signatures associated with response to neoadjuvant chemoradiotherapy in locally advanced rectal cancer. By analyzing a combination of multiple cohorts with bioinformatics approaches, we reveal biological pathways and immune‐related features that may improve ...
Aleksandra Stanojevic +10 more
wiley +1 more source
Molecular Oncology, EarlyView.Extracellular vesicle (EV) lipidomic profiling of plasma and ascites from patients with high‐grade serous ovarian cancer and of ovarian cancer cell lines reveals enrichment of triglycerides (TGs), diacylglycerols (DGs), phosphatidylcholine (PCs), sphingomyelins (SMs), reflecting tumor metabolic reprogramming.
Shikha Rani +9 more
wiley +1 more source
Extensions and variations of the two-person game on graphs [PDF]
, 2011 Khachatryan A. Extensions and variations of the two-person game on graphs.
Khachatryan, Anush
core
Testing the specifications of parametric models using anchoring vignettes
, 2014 Comparing assessments on a subjective scale across countries or socio-economic groups is often hampered by differences in response scales across groups.
Vonkova, H., van Soest, A.H.O.; id_orcid
core +1 more source
Molecular Oncology, EarlyView.High‐risk bladder cancer is typically treated with Bacillus Calmette‐Guérin (BCG), but 30–40% of patients relapse. No FDA‐ or CE‐approved biomarkers currently predict or prognosticate BCG failure. We systematically reviewed the literature and identified 72 eligible studies, revealing several promising biomarkers associated with BCG treatment response ...
Rui Ribeiro‐Pereira +7 more
wiley +1 more source
Molecular Oncology, EarlyView.In head and neck squamous cell carcinoma (HNSCC) p53 and p63 exert opposite roles on the transcription regulation of the lncRNA NEAT1. Under basal conditions, p53 levels are low and p63 represses NEAT1 expression. Upon genotoxic stress, p53 is rapidly induced, displacing p63 from the NEAT1 promoter leading to NEAT1 transcriptional activation and ...
Sara De Domenico +5 more
wiley +1 more source
Non-parametric production analysis under alternative price conditions. [PDF]
The literature on non-parametric production analysis has formulated tests for profit maximizing behavior that do not require a parametric specification of technology.
Kuosmanen, T, Cherchye, Laurens, Post, T
core
Hospitals universitários: avaliação comparativa de eficiência técnica
Economia Aplicada, 2000 This paper presents an exercise on comparative efficiency evaluation ofBrazilian federal university hospitals HUs (43 organizations). The methodology used is Data Envelopment Analysis - DEA, along with statistical non-parametric procedures and specific ...
Alexandre Marinho +1 more
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