Results 141 to 150 of about 702,666 (251)

Smooth transformation models for survival analysis: A tutorial using R. [PDF]

Stat Methods Med Res
Siegfried S, Tamási B, Hothorn T.
europepmc   +1 more source

Hyperosmotic stress‐induced redistribution of pre‐mRNA cleavage factor I subunits is associated with shifts in alternative polyadenylation

FEBS Open Bio, EarlyView.
Hyperosmotic stress triggers the relocation of the CFIm complex from the nucleus to the cytoplasm. This shift creates a nuclear ‘stoichiometric bottleneck’, limiting CFIm availability for mRNA processing. Consequently, specific mRNAs like NUDT21 and DICER1 undergo targeted 3′UTR shortening, demonstrating how spatial protein dynamics drive rapid ...
Hitomi Soumiya, Masatake Osawa, Hidefumi Fukumitsu   +2 more
wiley   +1 more source

Investigations of Intraoral Scan Body Extensions. Effect of Design on the Accuracy, Usability, and Feasibility for Digital Full-Arch Implant Scans In Vitro. [PDF]

Clin Oral Implants Res
Baranowski JH, Braian M, Stenport VF, Wennerberg A.   +3 more
europepmc   +1 more source

From energy provision to protein synthesis: Tunnelling nanotubes as mediators of intercellular metabolic cooperation in cancer

FEBS Open Bio, EarlyView.
The cytoskeleton‐mediated transport of mitochondria via tunnelling nanotubes restores respiration, increases ATP production, rescues cells from apoptosis, activates the AKT/mTOR signalling pathway, promotes cell migration and invasiveness, contributes to cancer progression and treatment resistance.
Stanislava Martínková, Jan Trnka
wiley   +1 more source

Weight Optimization of Steel Tied-Arch Footbridge. [PDF]

Materials (Basel)
Sokołowski D, Wudkiewicz T.
europepmc   +1 more source

MagmaFlow: A desktop platform for artificial intelligence‐driven expression analysis

FEBS Open Bio, EarlyView.
MagmaFlow is a free, no‐code platform for gene expression analysis. It generates interactive volcano plots, links genes to literature, pathways, and diseases, prioritizes candidates using millions of publications, identifies affected biological processes, builds network diagrams, and exports publication‐ready figures and reports for macOS and Windows ...
Carlos E. Buss, Ao Li, Eduardo H. Gilglioni, Mayank Bansal, Sumeet Pal Singh, Latifa Bakiri, Alessandra K. Cardozo, Esteban N. Gurzov   +7 more
wiley   +1 more source

Improving Parametric Mortgage Prepayment Models with Non-parametric Kernel Regression [PDF]

Developing a good prepayment model is a central task in the valuation of mortgages and mortgage-backed securities but conventional parametric models often have bad out-of-sample predictive ability.
Michael Marschoun, Michael LaCour-Little, Clark L. Maxam   +2 more
core  

Efficacy of a single-file reciprocating protocol vs. a multi-file rotary protocol on the removal of gutta-percha and ceraSeal sealer from oval canals: a volumetric and active instrumentation time analysis. [PDF]

Front Dent Med
Zorek A, Mahran AH, Nabeel M, Elsewify T.   +3 more
europepmc   +1 more source

Importin 7 mediates the nuclear import of HIV‐1 integrase via a specific interacting interface

FEBS Open Bio, EarlyView.
HIV‐1 integrase enables viral DNA integration into the host genome. By binding to the core domain of the host protein Importin 7 via its C‐terminal domain, the integrase is transported across the nuclear membrane into the nucleus, where integration of the viral genome into host DNA takes place. This translocation is a critical step for subsequent viral
Juana Bana, Avigail Yariv, Tal Oppenheim, Hadar Amartely, Dana Reichmann, Oded Livnah   +5 more
wiley   +1 more source

Economic Uncertainty Assessment Using a Combined Design of Experiments/Monte Carlo Simulation Approach with Application to an HSCT

, 1995
Presented at the 17th Annual Conference of the International Society of Parametric Analysts, San Diego, CA, May, 1995.Recently, the aerospace industry has felt the impact of the combined effect of increasing aircraft systems costs and budget restrictions
Bandte, Oliver, Mavris, Dimitri N.
core