Results 171 to 180 of about 566,253 (298)

A light‐triggered Time‐Resolved X‐ray Solution Scattering (TR‐XSS) workflow with application to protein conformational dynamics

FEBS Open Bio, EarlyView.
Time‐resolved X‐ray solution scattering captures how proteins change shape in real time under near‐native conditions. This article presents a practical workflow for light‐triggered TR‐XSS experiments, from data collection to structural refinement. Using a calcium‐transporting membrane protein as an example, the approach can be broadly applied to study ...
Fatemeh Sabzian‐Molaei, Fredrik Orädd, Konstantinos Magkakis, Magnus Andersson   +3 more
wiley   +1 more source

Survival parametric modeling for patients with heart failure based on Kernel learning. [PDF]

BMC Med Res Methodol
Montaseri M, Rezaei M, Khayati A, Mostafaei S, Taheri M.   +4 more
europepmc   +1 more source

Chameleon sequences reveal structural effects in proteins representing micelle‐like distribution of hydrophobicity

FEBS Open Bio, EarlyView.
Amino acids sequence of two different proteins with the same sequence (chameleon sequence—black boxes) represent in 3D structure of the proteins different secondary structures: HHHH—helical and BBB—Beta‐structural. The chains folded in water environment adopt different III‐order structures in which the chameleon fragments appear to adopt similar status
Irena Roterman, Katarzyna Stapor, Leszek Konieczny, Krzysztof Gądek, Piotr Nowakowski   +4 more
wiley   +1 more source

Utilizing SS-OCT and 3D parametric modeling to enhance IOL position prediction in cataract patients with long axial length. [PDF]

Front Med (Lausanne)
Li C, Luo B, Luo X, Zhang L, Li Q, Peng W.   +5 more
europepmc   +1 more source

Establishing an assay to evaluate d‐amino acid oxidase enzyme kinetics and inhibition using WST‐8 redox dye

FEBS Open Bio, EarlyView.
This study investigated a novel WST‐8‐based assay for evaluating d‐Amino acid oxidase (DAO) inhibitors. We confirmed its effectiveness using known inhibitors and found that uremic toxins possess relatively weak inhibitory activity compared to existing drugs.
Kahoko Miyake, Yuki Enoki, Yuka Nakazawa, Kazuaki Taguchi, Kazuaki Matsumoto   +4 more
wiley   +1 more source

L-GABS: Parametric Modeling of a Generic Active Lumbar Exoskeleton for Ergonomic Impact Assessment. [PDF]

Sensors (Basel)
Pérez-Soto M, Marín J, Marín JJ.
europepmc   +1 more source

Generalized Linear Models for Flexible Parametric Modeling of the Hazard Function. [PDF]

Med Decis Making, 2019
Kearns B, Stevenson MD, Triantafyllopoulos K, Manca A.   +3 more
europepmc   +1 more source

Analysing the significance of small conformational changes and low occupancy states in serial crystallographic data

FEBS Open Bio, EarlyView.
This protocol paper outlines methods to establish the success of a time‐resolved serial crystallographic experiment, by means of statistical analysis of timepoint data in reciprocal space and models in real space. We show how to amplify the signal from excited states to visualise structural changes in successful experiments.
Jake Hill, Yelyzaveta Pulnova, Elke De Zitter, Helen M. Ginn, Briony A. Yorke   +4 more
wiley   +1 more source

Parametric modeling and engineering application of the high-speed continuous beam bridge based on Building Information Modeling. [PDF]

PLoS One
Jiang H, Ma Z, Li Y, Wu D, Sai H, Zhang K, Chen K.   +6 more
europepmc   +1 more source

Hip Fracture Discrimination Based on Statistical Multi-parametric Modeling (SMPM). [PDF]

Ann Biomed Eng, 2019
Carballido-Gamio J, Yu A, Wang L, Su Y, Burghardt AJ, Lang TF, Cheng X.   +6 more
europepmc   +1 more source