Results 231 to 240 of about 9,489 (295)

PRMT1‐Mediated LDHA Methylation Drives STAT3 Lactylation to Orchestrate Intestinal Inflammation and Tumorigenesis

Advanced Science, EarlyView.
This study identifies an immunometabolic axis wherein SAM‐driven PRMT1 methylates LDHA, enhancing its activity. The resultant lactate induces STAT3 K709 lactylation, which stabilizes an active conformation to promote STAT3 phosphorylation and IL‐10 expression.
Hui Wang, Mengyu Zhang, Weipeng Gong, Jiaxuan Wu, Junping Zhang, Wenxiu Zhang, Yue Liu, Kui Wang, Canhua Huang, Jun Zhou, Sijin Wu, Yan Li, Tianliang Li   +12 more
wiley   +1 more source

An acute bout of foam rolling of the biceps brachii does not affect upper extremity sensorimotor function: a randomized trial. [PDF]

BMC Musculoskelet Disord
Yeşilyaprak SS, Özden F.
europepmc   +1 more source

Microscale Mapping of Fiber Strain and Damage in Composite Wrinkled Laminates Using Computed Tomography Assisted Wide‐Angle X‐Ray Scattering

Advanced Science, EarlyView.
This study combines full‐field tomography with diffraction mapping to quantify radial (ε002$\varepsilon _{002}$) and axial (ε100$\varepsilon _{100}$) lattice strain in wrinkled carbon‐fiber specimens for the first time. Radial microstrain gradients (−14.5 µεMPa$\varepsilon \mathrm{MPa}$−1) are found to signal damage‐prone zones ahead of failure, which ...
Hoang Minh Luong, James Trevarthen, Igor Dolbnya, Wadwan Singhapong, Nicholas Pilato, Richard Butler, Jiraphant Srisuriyachot, Alexander J. G. Lunt   +7 more
wiley   +1 more source

Reliable discrimination of type 1 and type 2 diabetes by flow-through leukocyte-endothelium interactions exploiting advanced hydrodynamic detection parameters. [PDF]

Anal Bioanal Chem
Hermenejildo J, López-Doménech S, Pelechá-Salvador M, Morillas C, Rocha M, Miró M, Carrasco-Correa EJ.   +6 more
europepmc   +1 more source

NFAT1⁺ microglia promote antiinflammatory polarization and angiogenesis via the HAS3-HA-LYVE1 axis to improve ischemic stroke outcomes. [PDF]

Cell Mol Biol Lett
Zhang Y, Cao X, Song Y, Han X, Tian G, Tao D, Hou A, Han S.   +7 more
europepmc   +1 more source

A high-power plantar energy harvester with LSTM-KAN adaptive damping control. [PDF]

iScience
Wu P, Liu J, Chen W, Song X, Yuan M, Qian S, Cui J, Hou X, He J, Chou X.   +9 more
europepmc   +1 more source

Generalized additive model integrating multi-source data for short-term influenza forecasting in Shenzhen, China (2023-2025). [PDF]

Front Public Health
Li X, Lv Q, Xiao J, Chen Z, Deng A, Rong Z, Sun H, Xiao S, Fang S.   +8 more
europepmc   +1 more source

A sustainable hybrid FEA-AI optimization framework for multistage deep drawing of unidirectionally rolled copper micro-cups. [PDF]

Sci Rep
Sivam SPSS, Kesavan S, Santhosh AJ.
europepmc   +1 more source

Trends in hip and knee replacement length of stay and patient demographics in England: a population-based study of 1,455,842 primary procedures. [PDF]

BMC Med
French JMR, Deere K, Sayers A, Whitehouse MR.   +3 more
europepmc   +1 more source

Rolling of stimuli-bent cylindrical robots using contact finite element simulations.

Soft Matter
He S, Yu H, Kouwenhoven MBN, Paoletti P, Dijkstra M, Xuan C.   +5 more
europepmc   +1 more source