Results 91 to 100 of about 461,827 (310)

Tumor mutational burden as a determinant of metastatic dissemination patterns

Molecular Oncology, EarlyView.
This study performed a comprehensive analysis of genomic data to elucidate whether metastasis in certain organs share genetic characteristics regardless of cancer type. No robust mutational patterns were identified across different metastatic locations and cancer types.
Eduardo Candeal, Andrea Moreno‐Manuel, Miguel Salvadó‐Pertierra, Cristina Santos‐Vivas, Rebeca Sanz‐Pamplona   +4 more
wiley   +1 more source

A Parametric Hierarchical Planner for Experimenting Abstraction Techniques [PDF]

, 2003
This paper presents a parametric system, devised and implemented to perform hierarchical planning by delegating the actual search to an external planner (the "parameter") at any level of abstraction, including the ground one.
ARMANO, GIULIANO, CHERCHI G, VARGIU, ELOISA   +2 more
core  

Cross-dimensional Weighting for Aggregated Deep Convolutional Features

, 2016
We propose a simple and straightforward way of creating powerful image representations via cross-dimensional weighting and aggregation of deep convolutional neural network layer outputs.
A Babenko, A Mikulík, F Perronnin, G Tolias, G Tolias, H Jegou, PH Gosselin, Y Gong, Yannis Avrithis   +8 more
core   +1 more source

Identification of serum protein biomarkers for pre‐cancerous lesions associated with pancreatic ductal adenocarcinoma

Molecular Oncology, EarlyView.
This work identified serum proteins associated with pancreatic epithelial neoplasms (PanINs) and early‐stage PDAC. Proteomics screens assessed genetically engineered mice with abundant PanINs, KPC mice (Lox‐STOP‐Lox‐KrasG12D/+ Lox‐STOP‐Lox‐Trp53R172H/+ Pdx1‐Cre) before PDAC development and also early‐stage PDAC patients (n = 31), compared to benign ...
Hannah Mearns, Jaclyn S. Long, Sergio Lilla, Kelly Hodge, Marcus J. G. W. Ladds, Colin Nixon, Paula Fernández‐Palanca, Sara Zanivan, Pilar Acedo, Stephen P. Pereira, Kevin M. Ryan   +10 more
wiley   +1 more source

Internet Based Benchmarking [PDF]

We discuss the design of interactive, internet based benchmarking using parametric (statistical) as well as non-parametric (DEA) models. The user receives benchmarks and improvement potentials.
Bogetoft, Peter, Nielsen, Kurt
core   +1 more source

Full Lensing Analysis of Abell 1703: Comparison of Independent Lens-Modelling Techniques

, 2010
The inner mass-profile of the relaxed cluster Abell 1703 is analysed by two very different strong-lensing techniques applied to deep ACS and WFC3 imaging.
Abdelsalam, Abell, Abell, Adi Zitrin, Allen, Bade, Barkana, Benítez, Bouwens, Bradač, Bradač, Bradley, Broadhurst, Broadhurst, Broadhurst, Bruursema, Bruzual, Böhringer, Coble, Coe, Cooray, De Xivry, Deb, Diego, Duffy, Duffy, Elinor Medezinski, Estrada, Franx, Frye, Frye, Gavazzi, Halkola, Hennawi, Herwig Dejonghe, Holland Ford, Horesh, Jori Liesenborgs, Kausch, Keiichi Umetsu, Kneib, Kneib, Kneib, Koester, Kowalski, Larry Bradley, Leir, Lemze, Liesenborgs, Liesenborgs, Liesenborgs, Liesenborgs, Limousin, Limousin, Mead, Medezinski, Meneghetti, Merten, Narciso Benítez, Navarro, Navarro, Newman, Oguri, Okabe, Philippe Bekaert, Plummer, Richard, Richard, Riley, Riley, Rizza, Sadeh, Saha, Saha, Sharon, Stark, Stott, Struble, Struble, Sven De Rijcke, Tom Broadhurst, Umetsu, Umetsu, Umetsu, Valls-Gabaud, Yoel Rephaeli, Yolanda Jiménez-Teja, Zheng, Zitrin, Zitrin, Zitrin   +90 more
core   +1 more source

Targeted modulation of IGFL2‐AS1 reveals its translational potential in cervical adenocarcinoma

Molecular Oncology, EarlyView.
Cervical adenocarcinoma patients face worse outcomes than squamous cell carcinoma counterparts despite similar treatment. The identification of IGFL2‐AS1's differential expression provides a molecular basis for distinguishing these histotypes, paving the way for personalized therapies and improved survival in vulnerable populations globally.
Ricardo Cesar Cintra, Lucca Paolo Hsu Helmich, Daniel Rodrigues de Bastos, Laura Sichero, Patrícia Savio de Araujo‐Souza, Fabio Passetti, Luisa Lina Villa   +6 more
wiley   +1 more source

Josephson parametric amplifier based quantum noise limited amplifier development for axion search experiments in CAPP

Frontiers in Physics
This paper provides a comprehensive overview of the development of flux-driven Josephson Parametric Amplifiers (JPAs) as Quantum Noise Limited Amplifier for axion search experiments conducted at the Center for Axion and Precision Physics Research (CAPP ...
Sergey V. Uchaikin, Jinmyeong Kim, Jinmyeong Kim, Caǧlar Kutlu, Caǧlar Kutlu, Boris I. Ivanov, Jinsu Kim, Arjan F. van Loo, Arjan F. van Loo, Yasunobu Nakamura, Yasunobu Nakamura, Saebyeok Ahn, Seonjeong Oh, Minsu Ko, Minsu Ko, Yannis K. Semertzidis, Yannis K. Semertzidis   +16 more
doaj   +1 more source

IMPDH inhibition enhances cytarabine efficacy in SAMHD1‐expressing leukaemia cells via guanine nucleotide depletion

Molecular Oncology, EarlyView.
Cytarabine is a key therapy for acute myeloid leukaemia (AML), but its efficacy is limited by the dNTPase SAMHD1, which hydrolyses its active metabolite. Screening nucleotide biosynthesis inhibitors revealed that IMPDH inhibitors selectively sensitise SAMHD1‐proficient AML cells to cytarabine.
Miriam Yagüe‐Capilla, Christopher Dirks, Caroline Eiden, Sonja K. Fesenmayer, Femke M. Hormann, Yolande Klootsema, Ingrid Lilienthal, Si Min Zhang, Nikolas Herold, Sean G. Rudd   +9 more
wiley   +1 more source

A Particle Swarm Optimization Algorithm Based on Time-Space Weight for Helicopter Maritime Search and Rescue Decision-Making

IEEE Access, 2020
One of the important problems to be solved in maritime search and rescue (MSAR) is decision-making, and the premise of it is determining the mission area for search and rescue unit.
Zikun Chen, Hu Liu, Yongliang Tian, Rui Wang, Peisen Xiong, Guanghui Wu   +5 more
doaj   +1 more source