Results 51 to 60 of about 32,943,257 (245)
Degradation mechanism of the von Willebrand factor A2 domain by nattokinase
FEBS Letters, EarlyView.Nattokinase, a natto‐derived protease, exhibits potent antithrombotic effects. This study demonstrates that nattokinase directly cleaves the von Willebrand factor (vWF) A2 domain in vitro. Unlike the native regulator ADAMTS13, nattokinase degrades folded vWF independently of shear stress.
Ryuichi Hyakumoto +3 more
wiley +1 more source
FEBS Letters, EarlyView.We present robust protocols for the preparation of supported lipid bilayers (SLBs) incorporating either Salmonella smooth LPS or outer membrane vesicles (OMVs). We use a combination of quartz crystal microbalance with dissipation (QCM‐D) and fluorescence microscopy to both characterize the SLBs of various compositions and to probe their interactions ...
Hudson P. Pace +6 more
wiley +1 more source
Parametric Optimisation of a Trigenerative Small Scale Compressed Air Energy Storage System
Proceedings, 2019 Recently, major improvement on compressed air energy storage technology has been made by using the heat of compression for heating energy or using it to preheat the compressed air in the expansion phase and by demonstrating its ability to produce cooling
Mohamad Cheayb +3 more
doaj +1 more source
Experience from Parametric Rolling of Ships
, 2011 This chapter reviews three recent full-scale events with parametric rolling for Ro–Ro Large Car and Truck Carriers (LCTC). The events represent three principally different modes of parametric rolling: principal parametric resonance where the period of ...
Palmquist, Mikael, +5 more
core +1 more source
Modelling stem cell differentiation related processes—A practical overview for biologists
FEBS Letters, EarlyView.Stem cell differentiation is complex and difficult to control experimentally. This review introduces suitable computational modelling approaches that can support stem cell research, from mechanistic ODE and abstract models to multiscale and deep learning methods.
Ricco Zeegelaar +4 more
wiley +1 more source
Self-designing parametric geometries
, 2015 The thesis of this paper is that script-based geometry modelling offers the possibility of building `self-designing' intelligence into parametric airframe geometries.
Sobester, Andras, Andras Sobester
core +1 more source
Design and analysis strategies for robust microbiome ageing research
FEBS Letters, EarlyView.The gut microbiome changes with age and associates with age‐related morbidity and mortality, establishing it as a potential biomarker and intervention target for ageing. Realising this potential requires methodological rigour, yet distinguishing biological signals from methodological artefacts remains challenging across cohorts. This review provides an
Mark Olenik +5 more
wiley +1 more source
FEBS Letters, EarlyView.Cancer progression is regulated by the dynamic matrix code of the tumor microenvironment, which influences cellular behavior and disease development. Importantly, matrix remodeling in three‐dimensional cancer models more accurately reflects in vivo conditions compared to conventional two‐dimensional systems.
Sylvia Mangani +3 more
wiley +1 more source
Ohio Retirement Study Council comparative performance study
, 2000 Semiannual; -Apr. 17, 2002.; Description based on Jun. 20, 2000 issue; title from cover of PDF document (viewed Feb. 13, 2006).; Vol. for Oct. 10, 2001 - Apr.
Ohio Retirement Study Council
core
FEBS Letters, EarlyView.The process of internalization of the Shiga toxin A subunit via formation of a complex with the Shiga toxin B subunit, which specifically binds to the Gb3 receptor. The peptide is designed to act as a carrier of drugs into cancer cells. Here, we explored the potential of peptides derived from the catalytic A subunit of Shiga toxin (STxA) to be drug ...
Giulia Opassi +6 more
wiley +1 more source